Search Results - "Kim, Kanghwa"

Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling by Rhee, Sue Goo, Chae, Ho Zoon, Kim, Kanghwa

“…The observation that purified yeast glutamine synthetase is rapidly inactivated in a thiol-containing buffer yet retains activity in crude extracts containing…”
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Irreversible Oxidation of the Active-site Cysteine of Peroxiredoxin to Cysteine Sulfonic Acid for Enhanced Molecular Chaperone Activity by Lim, Jung Chae, Choi, Hoon-In, Park, Yu Sun, Nam, Hyung Wook, Woo, Hyun Ae, Kwon, Ki-Sun, Kim, Yu Sam, Rhee, Sue Goo, Kim, Kanghwa, Chae, Ho Zoon

“…The thiol (–SH) of the active cysteine residue in peroxiredoxin (Prx) is known to be reversibly hyperoxidized to cysteine sulfinic acid (–SO2H), which can be…”
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Reversing the Inactivation of Peroxiredoxins Caused by Cysteine Sulfinic Acid Formation by Woo, Hyun Ae, Chae, Ho Zoon, Hwang, Sung Chul, Yang, Kap-Seok, Kang, Sang Won, Kim, Kanghwa, Rhee, Sue Goo

“…The active-site cysteine of peroxiredoxins is selectively oxidized to cysteine sulfinic acid during catalysis, which leads to inactivation of peroxidase…”
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Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid by Yang, Kap-Seok, Kang, Sang Won, Woo, Hyun Ae, Hwang, Sung Chul, Chae, Ho Zoon, Kim, Kanghwa, Rhee, Sue Goo

“…By following peroxiredoxin I (Prx I)-dependent NADPH oxidation spectrophotometrically, we observed that Prx I activity decreased gradually with time. The decay…”
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Identification of a New Type of Mammalian Peroxiredoxin That Forms an Intramolecular Disulfide as a Reaction Intermediate by Seo, Min Seok, Kang, Sang Won, Kim, Kanghwa, Baines, Ivan C., Lee, Tae Hoon, Rhee, Sue Goo

“…Peroxidases of the peroxiredoxin (Prx) family contain a Cys residue that is preceded by a conserved sequence in the NH2-terminal region. A new type of…”
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Cyclophilin A Binds to Peroxiredoxins and Activates Its Peroxidase Activity by Lee, Sang Pil, Hwang, Young Sun, Kim, Yong Jun, Kwon, Ki-Sun, Kim, Hyung Jung, Kim, Kanghwa, Chae, Ho Zoon

“…Six distinct peroxiredoxin (Prx) proteins (Prx I-VI) from distinct genes have been identified in mammalian tissues. Prxs are members of a group of peroxidases…”
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Escherichia coli Periplasmic Thiol Peroxidase Acts as Lipid Hydroperoxide Peroxidase and the Principal Antioxidative Function during Anaerobic Growth by Cha, Mee-Kyung, Kim, Won-Cheol, Lim, Chang-Jin, Kim, Kanghwa, Kim, Il-Han

“…To clarify the enzymatic property of Escherichia coli periplasmic thiol peroxidase (p20), the specific peroxidase activity toward peroxides was compared with…”
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Regulation of Thioredoxin Peroxidase Activity by C-terminal Truncation by Koo, Kyung Hee, Lee, Songmi, Jeong, Soo Young, Kim, Eui Tae, Kim, Hyung Jung, Kim, Kanghwa, Song, Kiwon, Chae, Ho Zoon

“…Thioredoxin peroxidase is a member of peroxiredoxin (Prx) family, which uses a thioredoxin (Trx) as an immediate electron donor for the reduction of peroxide…”
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Screening Molecular Chaperones Similar to Small Heat Shock Proteins in Schizosaccharomyces pombe by Han, Jiyoung, Kim, Kanghwa, Lee, Songmi

“…To screen molecular chaperones similar to small heat shock proteins (sHsps), but without α-crystalline domain, heatstable proteins from Schizosaccharomyces…”
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Novel Protective Mechanism against Irreversible Hyperoxidation of Peroxiredoxin by Seo, Jae Ho, Lim, Jung Chae, Lee, Duck-Yeon, Kim, Kyung Seok, Piszczek, Grzegorz, Nam, Hyung Wook, Kim, Yu Sam, Ahn, Taeho, Yun, Chul-Ho, Kim, Kanghwa, Chock, P. Boon, Chae, Ho Zoon

“…Peroxiredoxins (Prxs) are a group of peroxidases containing a cysteine thiol at their catalytic site. During peroxidase catalysis, the catalytic cysteine,…”
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Purification and Characterization of a Second Type Thioredoxin Peroxidase (Type II TPx) from Saccharomyces cerevisiae by Jeong, Jin Sook, Kwon, Soo Jin, Kang, Sang Won, Rhee, Sue Goo, Kim, Kanghwa

“…A yeast peroxidase that reduces H2O2 and alkyl hydroperoxides with the use of reducing equivalents provided by thioredoxin was identified previously and named…”
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The Tetrameric Structure of Haemophilus influenzaHybrid Prx5 Reveals Interactions between Electron Donor and Acceptor Proteins by Kim, Seung Jun, Woo, Joo Rang, Hwang, Young Sun, Jeong, Dae Gwin, Shin, Dong Hae, Kim, Kanghwa, Ryu, Seong Eon

“…Cellular redox control is often mediated by oxidation and reduction of cysteine residues in the redox-sensitive proteins, where thioredoxin and glutaredoxin…”
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Anti-inflammatory effects of sucrose-derived oligosaccharides produced by a constitutive mutant L. mesenteroides B-512FMCM dextransucrase in high fat diet-fed mice by Kang, Min-Gyung, Lee, Hee Jae, Cho, Jae-Young, Kim, Kanghwa, Yang, Soo Jin, Kim, Doman

“…Oligosaccharide (OS) is used as a sugar replacement as well as an ingredient in functional foods because of its beneficial effects, mainly on reducing calorie…”
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Structural and biochemical analyses reveal ubiquitin C-terminal hydrolase-L1 as a specific client of the peroxiredoxin II chaperone by Lee, Sang Pil, Park, Chan Mi, Kim, Kyung Seok, Kim, Eunji, Jeong, Moonkyung, Shin, Ji-Young, Yun, Chul-Ho, Kim, Kanghwa, Chock, P. Boon, Chae, Ho Zoon

“…Peroxiredoxins (Prxs) play dual roles as both thiol-peroxidases and molecular chaperones. Peroxidase activity enables various intracellular functions, however,…”
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Chaperoning activity of peroxiredoxins protects brain‐type creatine kinase under various stresses through specific interaction by Rakhmetov, Anar, Lee, Sang Pil, Kim, Kanghwa, Chae, Ho Zoon

“…Abstract only Peroxiredoxins (Prxs) are a family of peroxidase proteins which, although, exhibit chaperone activity due to the structural transition from dimer…”
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Peroxiredoxin, a Novel Family of Peroxidases by Rhee, Sue Goo, Kang, Sang Won, Chang, Tong‐Shin, Jeong, Woojin, Kim, Kanghwa

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Novel Protective Mechanism against Irreversible Hyperoxidation of Peroxiredoxin: Nα-TERMINAL ACETYLATION OF HUMAN PEROXIREDOXIN II by Seo, Jae Ho, Lim, Jung Chae, Lee, Duck-Yeon, Kim, Kyung Seok, Piszczek, Grzegorz, Nam, Hyung Wook, Kim, Yu Sam, Ahn, Taeho, Yun, Chul-Ho, Kim, Kanghwa, Chock, P. Boon, Chae, Ho Zoon

“…Peroxiredoxins (Prxs) are a group of peroxidases containing a cysteine thiol at their catalytic site. During peroxidase catalysis, the catalytic cysteine,…”
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Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha by Kang, S W, Chae, H Z, Seo, M S, Kim, K, Baines, I C, Rhee, S G

“…Mammalian tissues express three immunologically distinct peroxiredoxin (Prx) proteins (Prx I, II, and III), which are the products of distinct genes. With the…”
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Strand breaks in DNA induced by a thiol/Fe(III)/O2 mixed-function oxidase system and its protection by a yeast antioxidant protein by Kwon, S J, Kim, K, Kim, I H, Yoon, I K, Park, J W

“…Strand breaks can be produced in pBluescript plasmid DNA and calf thymus DNA by a mixed-function oxidase (MFO) system comprised of Fe3+, O2, and dithiothreitol…”
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Client Specific Chaperoning Activity of Peroxiredoxin by Park, Chan Mi, Lee, Sang Pil, Kim, Kanghwa, Chae, Ho Zoon

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