Search Results - "Kim, Juyong B"

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis by Wirka, Robert C., Wagh, Dhananjay, Paik, David T., Pjanic, Milos, Nguyen, Trieu, Miller, Clint L., Kundu, Ramen, Nagao, Manabu, Coller, John, Koyano, Tiffany K., Fong, Robyn, Woo, Y. Joseph, Liu, Boxiang, Montgomery, Stephen B., Wu, Joseph C., Zhu, Kuixi, Chang, Rui, Alamprese, Melissa, Tallquist, Michelle D., Kim, Juyong B., Quertermous, Thomas

“…In response to various stimuli, vascular smooth muscle cells (SMCs) can de-differentiate, proliferate and migrate in a process known as phenotypic modulation…”
Get full text

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci by Miller, Clint L., Pjanic, Milos, Wang, Ting, Nguyen, Trieu, Cohain, Ariella, Lee, Jonathan D., Perisic, Ljubica, Hedin, Ulf, Kundu, Ramendra K., Majmudar, Deshna, Kim, Juyong B., Wang, Oliver, Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Assimes, Themistocles L., Montgomery, Stephen B., Schadt, Eric E., Björkegren, Johan L.M., Quertermous, Thomas

“…Coronary artery disease (CAD) is the leading cause of mortality and morbidity, driven by both genetic and environmental risk factors. Meta-analyses of…”
Get full text

Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci by Sazonova, Olga, Zhao, Yuqi, Nürnberg, Sylvia, Miller, Clint, Pjanic, Milos, Castano, Victor G, Kim, Juyong B, Salfati, Elias L, Kundaje, Anshul B, Bejerano, Gill, Assimes, Themistocles, Yang, Xia, Quertermous, Thomas

“…To functionally link coronary artery disease (CAD) causal genes identified by genome wide association studies (GWAS), and to investigate the cellular and…”
Get full text

Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap by Nurnberg, Sylvia T, Cheng, Karen, Raiesdana, Azad, Kundu, Ramendra, Miller, Clint L, Kim, Juyong B, Arora, Komal, Carcamo-Oribe, Ivan, Xiong, Yiqin, Tellakula, Nikhil, Nanda, Vivek, Murthy, Nikitha, Boisvert, William A, Hedin, Ulf, Perisic, Ljubica, Aldi, Silvia, Maegdefessel, Lars, Pjanic, Milos, Owens, Gary K, Tallquist, Michelle D, Quertermous, Thomas

“…Recent genome wide association studies have identified a number of genes that contribute to the risk for coronary heart disease. One such gene, TCF21, encodes…”
Get full text

Left Ventricular Hypertrophy and Biomarkers of Cardiac Damage and Stress in Aortic Stenosis by Stein, Elliot J, Fearon, William F, Elmariah, Sammy, Kim, Juyong B, Kapadia, Samir, Kumbhani, Dharam J, Gillam, Linda, Whisenant, Brian, Quader, Nishath, Zajarias, Alan, Welt, Frederick G, Bavry, Anthony A, Coylewright, Megan, Piana, Robert N, Mallugari, Ravinder R, Clark, Daniel E, Patel, Jay N, Gonzales, Holly, Gupta, Deepak K, Vatterott, Anna, Jackson, Natalie, Huang, Shi, Lindman, Brian R

“…Background Left ventricular hypertrophy (LVH) is associated with increased mortality risk and rehospitalization after transcatheter aortic valve replacement…”
Get full text

The Effect of Transvenous Pacemaker and Implantable Cardioverter Defibrillator Lead Placement on Tricuspid Valve Function: An Observational Study by Kim, Juyong B., MD, MPH, Spevack, Daniel M., MD, Tunick, Paul A., MD, Bullinga, John R., MD, Kronzon, Itzhak, MD, Chinitz, Larry A., MD, Reynolds, Harmony R., MD

“…This study assessed the effect of transtricuspid placement of permanent pacemaker (PPM) and implantable cardioverter defibrillator (ICD) leads on tricuspid…”
Get full text

Global Longitudinal Strain and Biomarkers of Cardiac Damage and Stress as Predictors of Outcomes After Transcatheter Aortic Valve Implantation by Perry, Andrew S., Stein, Elliot J., Biersmith, Michael, Fearon, William F., Elmariah, Sammy, Kim, Juyong B., Clark, Daniel E., Patel, Jay N., Gonzales, Holly, Baker, Michael, Piana, Robert N., Mallugari, Ravinder R., Kapadia, Samir, Kumbhani, Dharam J., Gillam, Linda, Whisenant, Brian, Quader, Nishath, Zajarias, Alan, Welt, Frederick G., Bavry, Anthony A., Coylewright, Megan, Gupta, Deepak K., Vatterott, Anna, Jackson, Natalie, Huang, Shi, Lindman, Brian R.

“…Background Global longitudinal strain (GLS) is a sensitive measure of left ventricular function and a risk marker in severe aortic stenosis. We sought to…”
Get full text

Immunologic effects of forest fire exposure show increases in IL‐1β and CRP by Prunicki, Mary M., Dant, Christopher C., Cao, Shu, Maecker, Holden, Haddad, Francois, Kim, Juyong B., Snyder, Michael, Wu, Joseph, Nadeau, Kari

Get full text

Reduced Pulmonary Artery Distensibility Predicts Persistent Pulmonary Hypertension and 2-Year Mortality in Patients with Severe Aortic Stenosis Undergoing TAVR by Turner, Valery, Maret, Eva, Kim, Juyong B., Codari, Marina, Hinostroza, Virginia, Mastrodicasa, Domenico, Watkins, A. Claire, Fearon, William F., Fischbein, Michael P., Haddad, Francois, Willemink, Martin J., Fleischmann, Dominik

“…Post-TAVR persistent pulmonary hypertension (PH) is a better predictor of poor outcome than pre-TAVR PH. In this longitudinal study we sought to evaluate…”
Get full text

Association of Depression and Cognitive Dysfunction With Patient-Centered Outcomes After Transcatheter Aortic Valve Replacement by El-Sabawi, Bassim, Cloud, Harrison, Patel, Jay N, Bell, Susan P, Elmariah, Sammy, Fearon, William F, Kim, Juyong B, Piana, Robert N, Kapadia, Samir R, Kumbhani, Dharam J, Gillam, Linda D, Whisenant, Brian K, Quader, Nishath, Zajarias, Alan, Welt, Frederick G, Bavry, Anthony A, Coylewright, Megan, Vatterott, Anna, Jackson, Natalie, Huang, Shi, Lindman, Brian R

“…Depression and cognitive dysfunction (CD) are not routinely screened for in patients before transcatheter aortic valve replacement (TAVR) and their association…”
Get full text

Associations of Sarcopenia and Body Composition Measures With Mortality After Transcatheter Aortic Valve Replacement by Stein, Elliot J, Neill, Colin, Nair, Sangeeta, Terry, J Greg, Carr, J Jeffrey, Fearon, William F, Elmariah, Sammy, Kim, Juyong B, Kapadia, Samir, Kumbhani, Dharam J, Gillam, Linda, Whisenant, Brian, Quader, Nishath, Zajarias, Alan, Welt, Frederick G, Bavry, Anthony A, Coylewright, Megan, Piana, Robert, Mallugari, Ravinder R, Vatterott, Anna, Jackson, Natalie, Huang, Shi, Lindman, Brian R

“…Frailty associates with worse outcomes after transcatheter aortic valve replacement (TAVR). Sarcopenia underlies frailty, but the association between a…”
Get full text

Genetics and Genomics of Coronary Artery Disease by Pjanic, Milos, Miller, Clint L., Wirka, Robert, Kim, Juyong B., DiRenzo, Daniel M., Quertermous, Thomas

“…Coronary artery disease (or coronary heart disease), is the leading cause of mortality in many of the developing as well as the developed countries of the…”
Get full text

Utility of High-Sensitivity and Conventional Troponin in Patients Undergoing Transcatheter Aortic Valve Replacement: Incremental Prognostic Value to B-type Natriuretic Peptide by Kobayashi, Yukari, Kim, Juyong B., Moneghetti, Kegan J., Fischbein, Michael, Lee, Anson, Watkins, Claire A., Yeung, Alan C., Liang, David, Ozen, Mehmet O., Demirci, Utkan, Bowen, Raffick, Fearon, William F., Haddad, Francois

“…High-sensitivity Troponin (hs-Tn) has emerged as a useful marker for patients with myocardial injury or heart failure. However, few studies have compared…”
Get full text

Metabolic Signatures of Cardiac Dysfunction, Multimorbidity, and Post-Transcatheter Aortic Valve Implantation Death by Perry, Andrew S, Zhao, Shilin, Murthy, Venkatesh, Gupta, Deepak K, Fearon, William F, Kim, Juyong B, Kapadia, Samir, Kumbhani, Dharam J, Gillam, Linda, Whisenant, Brian, Quader, Nishath, Zajarias, Alan, Mallugari, Ravinder R, Clark, Daniel E, Patel, Jay N, Gonzales, Holly, Welt, Frederick G, Bavry, Anthony A, Coylewright, Megan, Piana, Robert N, Vatterott, Anna, Jackson, Natalie, Gerszten, Robert E, Lindman, Brian R, Shah, Ravi, Elmariah, Sammy

“…Background Studies in mice and small patient subsets implicate metabolic dysfunction in cardiac remodeling in aortic stenosis, but no large comprehensive…”
Get full text

Dynamic changes in aortic impedance after transcatheter aortic valve replacement and its impact on exploratory outcome by Kobayashi, Yukari, Kim, Juyong B., Moneghetti, Kegan J., Kobayashi, Yuhei, Zhang, Ran, Brenner, Daniel A., O’Malley, Ryan, Schnittger, Ingela, Fischbein, Michael, Miller, D. Craig, Yeung, Alan C., Liang, David, Haddad, Francois, Fearon, William F.

“…Valvulo-arterial impedance (Zva) has been shown to predict worse outcome in medically managed aortic stenosis (AS) patients. We aimed to investigate the…”
Get full text

Incremental Value of Deformation Imaging and Hemodynamics Following Heart Transplantation: Insights From Graft Function Profiling by Kobayashi, Yukari, Sudini, Naga Lakshmi, Rhee, June-Wha, Aymami, Marie, Moneghetti, Kegan J, Bouajila, Sara, Kobayashi, Yuhei, Kim, Juyong B, Schnittger, Ingela, Teuteberg, Jeffery J, Khush, Kiran K, Fearon, William F, Haddad, Francois

“…This study investigated to define graft dysfunction and to determine its incremental association with long-term outcome after heart transplantation (HT)…”
Get full text

TCT-645 Poorer Left Ventricular Global Longitudinal Strain and Less Tricuspid Regurgitation Predicts Improvement in Left Ventricular Function Following Transcatheter Aortic Valve Replacement by Kim, Juyong B, Brenner, Daniel, Kobayashi, Yukari, O'Malley, Ryan, Kobayashi, Yuhei, Dao, Catherine, Vu, Thu, Yeung, Alan, Miller, D. Craig, Fischbein, Michael, Wu, Joseph C, Haddad, Francois, Fearon, William F

“…Patients were divided into improvement and deterioration groups according to change in LV ejection fraction (EF) before and 1 month after TAVR…”
Get full text

Abstract 145: Chronic Electronic Cigarette Exposure Accelerates SMC Phenotypic Modulation And Activates The NMDA-type Glutamate Receptor (NMDAR) Pathway In Mediating Vascular Calcification by Damiani, Isabella, Weldy, Chad, Easwaran, Meena, Qin, Guyu, Basu, Sugandha, Direnzo, Elizabeth, Quertermous, Thomas, Kim, Juyong B

“…Abstract only Introduction: Electronic cigarettes pose a serious emerging threat to cardiovascular health. The use of electronic nicotine delivery systems…”
Get full text

Abstract 12441: Ambient Fine Particulate Matter Air Pollution but Not Ozone is Associated With Elevated Risk of All-Cause Hospitalization in Patients With a Prior Diagnosis of Atrial Fibrillation by Horne, Benjamin D, Haddad, Francois, Joy, Elizabeth A, Prunicki, Mary, Anderson, Jeffrey L, Kim, Juyong B, Bride, Daniel, Bair, Tami L, Nadeau, Kari, Knowlton, Kirk U

“…Abstract only Introduction: Short-term increases (days to weeks) in fine particulate matter (PM 2.5 ) air pollution are associated with atrial fibrillation…”
Get full text

Abstract 12409: Ambient Fine Particulate Matter and Ozone Air Pollution Are Differentially Associated With Hospitalization for Unstable Angina and Acute Myocardial Infarction During Wildfire and Inversion Seasons by Horne, Benjamin D, Haddad, Francois, Joy, Elizabeth A, Kim, Juyong B, Anderson, Jeffrey L, Prunicki, Mary, Bride, Daniel, Bair, Tami L, Nadeau, Kari C, Knowlton, Kirk U

“…Abstract only Background: Short-term increases (days to weeks) in fine particulate matter (PM 2.5 ) air pollution are associated with hospitalization for acute…”
Get full text