Search Results - "Kim, Jin Yung"

Anti-Aging Effect of the Ketone Metabolite β-Hydroxybutyrate in Drosophila Intestinal Stem Cells by Park, Joung-Sun, Kim, Yung-Jin

“…Age-related changes in tissue-resident adult stem cells may be closely linked to tissue aging and age-related diseases, such as cancer. β-Hydroxybutyrate is…”
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Computer simulation approach to the identification of visfatin-derived angiogenic peptides by Choi, Ji Myung, Vuppala, Srimai, Park, Min Jung, Kim, Jaeyoung, Jegal, Myeong-Eun, Han, Yu-Seon, Kim, Yung-Jin, Jang, Joonkyung, Jeong, Min-Ho, Joo, Bo Sun

“…Angiogenesis plays an essential role in various normal physiological processes, such as embryogenesis, tissue repair, and skin regeneration. Visfatin is a 52…”
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Hispidulin Inhibits the Vascular Inflammation Triggered by Porphyromonas gingivalis Lipopolysaccharide by Kim, Yeon, Lee, Hoyong, Park, Hyun-Joo, Kim, Mi-Kyoung, Kim, Yong-Il, Kim, Hyung Joon, Bae, Soo-Kyung, Kim, Yung-Jin, Bae, Moon-Kyoung

“…Hispidulin is a natural bioactive flavonoid that has been studied for its potential therapeutic properties, including its anti-inflammatory, antioxidant, and…”
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C-terminal region of HBx is crucial for mitochondrial DNA damage by Jung, Seung-Youn, Kim, Yung-Jin

“…Highlights ► HBx produces 8-oxoguanine, a biomarker of oxidative DNA damage, in liver cells. ► HBx induces ROS production and mitochondrial DNA damage. ► HBx…”
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Melatonin suppresses tumor angiogenesis by inhibiting HIF-1α stabilization under hypoxia by Park, Shi-Young, Jang, Won-Jun, Yi, Eui-Yeun, Jang, Ji-Yeong, Jung, Yunjin, Jeong, Joo-Won, Kim, Yung-Jin

“…:  Angiogenesis is an important mediator of tumor progression. As tumors expand, diffusion distances from the existing vascular supply increases, resulting in…”
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Cancer Stem-Like Phenotype of Mitochondria Dysfunctional Hep3B Hepatocellular Carcinoma Cell Line by Han, Yu-Seon, Yi, Eui-Yeun, Jegal, Myeong-Eun, Kim, Yung-Jin

“…Mitochondria are major organelles that play various roles in cells, and mitochondrial dysfunction is the main cause of numerous diseases. Mitochondrial…”
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SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier by Kim, Kyu-Won, Lee, Sae-Won, Kim, Woo Jean, Choi, Yoon Kyung, Song, Hyun Seok, Son, Myung Jin, Gelman, Irwin H, Kim, Yung-Jin

“…The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and low permeability. BBB maintenance is important in the central nervous system…”
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The matrix metalloproteinase-7 regulates the extracellular shedding of syndecan-2 from colon cancer cells by Choi, Sojoong, Kim, Jin-Yung, Park, Jun Hyoung, Lee, Seung-Teak, Han, Inn-Oc, Oh, Eok-Soo

“…► Overexpression of MMP-7 enhances syndecan-2 shedding. ► MMP-7 enhances the shedding of syndecan-2 from human colon cancer cells. ► MMP-7 cleaved syndecan-2…”
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Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells by Jung, Seung-Youn, Jeon, Hye-Kyung, Choi, Jae-Sun, Kim, Yung-Jin

“…Cells under hypoxic stress either activate an adaptive response or undergo cell death. Although some mechanisms have been reported, the exact mechanism behind…”
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Quercetin activates an angiogenic pathway, hypoxia inducible factor (HIF)-1-vascular endothelial growth factor, by inhibiting HIF-prolyl hydroxylase: a structural analysis of quercetin for inhibiting HIF-prolyl hydroxylase by Jeon, Hyunchu, Kim, Heejung, Choi, Daekyu, Kim, Duksoo, Park, Shi-Young, Kim, Yung-Jin, Kim, Young Mi, Jung, Yunjin

“…We investigated a molecular mechanism underlying quercetin-mediated amelioration of colonic mucosal injury and analyzed chemical structure contributing to the…”
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Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer by Song, In‐Sung, Ha, Ga‐Hee, Kim, Jeong‐Min, Jeong, So‐Young, Lee, Han‐Chul, Kim, Yong Sung, Kim, Yung‐Jin, Kwon, Taeg Kyu, Kim, Nam‐Soon

“…In a previous study, human ZNF312b was identified as a cell proliferation‐associated oncogene via the K‐ras/extracellular signal‐regulated kinase cascade in…”
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The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut by Park, Joung-Sun, Na, Hyun-Jin, Kim, Yung-Jin

“…Adult stem cells are pivotal for maintaining tissue homeostasis, and their functional decline is linked to aging and its associated diseases, influenced by the…”
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Thromboxane A2 increases endothelial permeability through upregulation of interleukin-8 by Kim, Su-Ryun, Bae, Soo-Kyung, Park, Hyun-Joo, Kim, Mi-Kyoung, Kim, Koanhoi, Park, Shi-Young, Jang, Hye-Ock, Yun, Il, Kim, Yung-Jin, Yoo, Mi-Ae, Bae, Moon-Kyoung

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Caffeic acid phenethyl ester-mediated Nrf2 activation and IκB kinase inhibition are involved in NFκB inhibitory effect: Structural analysis for NFκB inhibition by Lee, Youna, Shin, Dong-ha, Kim, Ji-Hye, Hong, Sungchae, Choi, Daekyu, Kim, Yung-Jin, Kwak, Mi-Kyoung, Jung, Yunjin

“…Caffeic acid phenethyl ester (CAPE) is an active component of propolis from honeybee. We investigated potential molecular mechanisms underlying CAPE-mediated…”
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Design, synthesis, and biological testing of thiosalicylamides as a novel class of calcium channel blockers by Mehanna, Ahmed S., Kim, Jin Yung

“…[Display omitted] The current research aimed to investigate the importance of the heterocyclic ring system in the structure of the cardiovascular drug…”
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Differential virulence of infectious hematopoietic necrosis virus (IHNV) isolated from salmonid fish in Gangwon Province, Korea by Kim, So-Sun, Kim, Kwang-Il, Yoo, Hae-Kyun, Han, Yu-Seon, Jegal, Myeong-Eun, Byun, Soon-Gyu, Lim, Hyun-Jeong, Park, Jang-Su, Kim, Yung-Jin

“…The present study investigated the virulence and expression of innate immunity genes in isolates of infectious hematopoietic necrosis virus (IHNV) in Gangwon…”
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Mitochondrial dysfunction induces EMT through the TGF-β/Smad/Snail signaling pathway in Hep3B hepatocellular carcinoma cells by YI, EUI-YEUN, PARK, SHI-YOUNG, JUNG, SEUNG-YOUN, JANG, WON-JUN, KIM, YUNG-JIN

“…Mitochondrial dysfunction has been found to be associated with various pathological conditions, particularly cancer. However, the mechanisms underlying tumor…”
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C-terminal truncated HBx reduces doxorubicin cytotoxicity via ABCB1 upregulation in Huh-7 hepatocellular carcinoma cells by Jegal, Myeong-Eun, Jung, Seung-Youn, Han, Yu-Seon, Kim, Yung-Jin

“…Hepatitis B virus (HBV) encoding the HBV x protein (HBx) is a known causative agent of hepatocellular carcinoma (HCC). Its pathogenic activities in HCC include…”
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The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae by Chen, G C, Kim, Y J, Chan, C S

“…BEM2 of Saccharomyces cerevisiae encodes a Rho-type GTPase-activating protein that is required for proper bud site selection at 26 degrees C and for bud…”
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Betaine inhibits in vitro and in vivo angiogenesis through suppression of the NF-κB and Akt signaling pathways by YI, EUI-YEUN, KIM, YUNG-JIN

“…Angiogenesis is defined as the formation of new blood vessels form existing vessels surrounding a tumor. The process of angiogenesis is an important step for…”
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