Search Results - "Kim, JiSook"
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Natural evolution of ductus arteriosus with noninterventional conservative management in extremely preterm infants born at 23-28 weeks of gestation
Published in PloS one (13-02-2019)“…This study aimed to determine the natural course of patent ductus arteriosus (PDA) with noninterventional conservative management and whether the presence…”
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Delayed Establishment of Gut Microbiota in Infants Delivered by Cesarean Section
Published in Frontiers in microbiology (11-09-2020)“…The maternal vaginal microbiome is an important source for infant gut microbiome development. However, infants delivered by Cesarean section (CS) do not…”
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Increased risk of refeeding syndrome-like hypophosphatemia with high initial amino acid intake in small-for-gestational-age, extremely-low-birthweight infants
Published in PloS one (23-08-2019)“…Recent nutrition guidelines for extremely-low-birth-weight infants (ELBWIs) recommend implementation of high initial amino acid (AA) supplementation in…”
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Synthesis and biological evaluation of novel thienopyrimidine derivatives as diacylglycerol acyltransferase 1 (DGAT-1) inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2020)“…A novel series of thieno[3,2-d]pyrimidine derivatives were synthesised and their inhibitory effects against diacylglycerol acyltransferase 1 (DGAT-1) were…”
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Design, Synthesis, and Biological Evaluation of Imidazopyrazinone Derivatives as Antagonists of Inhibitor of Apoptosis Proteins (IAPs)
Published in Bulletin of the Korean Chemical Society (01-06-2021)“…Apoptosis inhibitor (IAP) proteins are overexpressed in many cancers and implicated in tumor growth, so the development of antagonist that disrupts with the…”
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Corrigendum: Tolerability and Effect of Early High-Dose Amino Acid Administration in Extremely Low Birth Weight Infants
Published in Neonatal medicine (Seoul, Korea) (01-02-2020)“…KCI Citation Count: 0…”
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Tolerability and Effect of Early High-Dose Amino Acid Administration in Extremely Low Birth Weight Infants
Published in Neonatal medicine (Seoul, Korea) (30-11-2018)“…Purpose The aim of this study is to examine the tolerability and effect of early high-dose amino acid administration in extremely low birth weight infants…”
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Inactivation of bovine plasma amine oxidase by haloallylamines
Published in Bioorganic & medicinal chemistry (01-03-2006)“…Various 2- and 3-haloallylamines were synthesized and evaluated as inhibitors of the quinone-dependent bovine plasma amine oxidase (BPAO). 3-Haloallylamines,…”
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Structure–activity relationship studies of Imidazo[1′,2′:1,6]pyrido[2,3-d]pyrimidine derivatives to develop selective FGFR inhibitors as anticancer agents for FGF19-overexpressed hepatocellular carcinoma
Published in European journal of medicinal chemistry (15-01-2025)“…The aberrant activation of fibroblast growth factor (FGF) and FGF receptor (FGFR)-mediated signaling pathways are associated with cancer development, including…”
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Discovery of 2,6-Naphthyridine Analogues as Selective FGFR4 Inhibitors for Hepatocellular Carcinoma
Published in Journal of medicinal chemistry (23-05-2024)“…Hepatocellular carcinoma (HCC) is the most common type of liver cancer and is responsible for 90% of cases. Approximately 30% of patients diagnosed with HCC…”
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Longitudinal bone growth is impaired by direct involvement of caffeine with chondrocyte differentiation in the growth plate
Published in Journal of anatomy (01-01-2017)“…We showed previously that caffeine adversely affects longitudinal bone growth and disrupts the histomorphometry of the growth plate during the pubertal growth…”
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Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model
Published in Clinical & experimental metastasis (01-04-2023)“…Brain metastasis is a common complication in melanoma patients with BRAF and NRAS mutations and has a poor prognosis. Although BRAF inhibitors are clinically…”
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Abstract 1474: Antitumor activity of belvarafenib in melanoma brain metastasis and NRAS mutation melanoma models
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Over the past decade, BRAF inhibitors, either alone or in combination with MEK inhibitors, have set a new milestone in the treatment of patients with BRAF V600…”
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Design, synthesis and biological evaluation of new bivalent quinazoline analogues as IAP antagonists
Published in Bioorganic & medicinal chemistry letters (15-02-2021)“…[Display omitted] We recently reported the biological evaluations of monovalent IAP antagonist 7 with good potency (MDA-MB-231, IC50 = 19 nM). In an effort to…”
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Structure-activity relationship studies of Imidazo1',2':1,6pyrido2,3-dpyrimidine derivatives to develop selective FGFR inhibitors as anticancer agents for FGF19-overexpressed hepatocellular carcinoma
Published in European journal of medicinal chemistry (12-11-2024)“…The aberrant activation of fibroblast growth factor (FGF) and FGF receptor (FGFR)-mediated signaling pathways are associated with cancer development, including…”
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Inactivation of bovine plasma amine oxidase by 1,1,1–trihalo–3–aminopropanes
Published in Bioorganic chemistry (01-12-2017)“…[Display omitted] •Trihaloaminopropane analogs were synthesized as inactivators for BPAO.•Trihaloaminopropane analogs were found to be irreversible…”
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Influence of solar glare intensity on vehicular speed variance
Published in Journal of transport & health (01-03-2021)“…Studies in weather-affected traffic collisions have mainly focused on rain and snow, which can be referred to as highly variable and non-recurrent events. On…”
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Abstract 3833: Antitumor activity of novel reversible LSD1 inhibitor in preclinical models of AML and SCLC
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Introduction: Global changes in the epigenetic landscape are known as the hallmark in cancer and the histone demethylase Lysine-specific demethylase 1 (LSD1)…”
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Abstract 1293: HM43239, a novel FLT3 inhibitor in overcoming resistance for acute myeloid leukemia
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Introduction: Acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 (FLT3) mutation is associated with poor prognosis with a high risk of relapse after…”
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