Search Results - "Kim, Ji Hyang"

Primaquine Inhibits the Endosomal Trafficking and Nuclear Localization of EGFR and Induces the Apoptosis of Breast Cancer Cells by Nuclear EGFR/Stat3-Mediated c-Myc Downregulation by Kim, Ji-Hyang, Choi, Hack-Sun, Lee, Dong-Sun

“…Triple-negative breast cancer (TNBC) cells overexpress the epidermal growth factor receptor (EGFR). Nuclear EGFR (nEGFR) drives resistance to anti-EGFR therapy…”
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Dihydrotanshinone-Induced NOX5 Activation Inhibits Breast Cancer Stem Cell through the ROS/Stat3 Signaling Pathway by Kim, Ki-Seok, Jeong, Dong Kee, Kim, Ji-Hyang, Choi, Hack Sun, Kim, Su-Lim, Lee, Dong-Sun

“…Cancer stem cells (CSCs) are known to mediate metastasis and recurrence and are therefore a promising therapeutic target. In this study, we found that…”
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Triterpene Acid ( 3 - O - p -Coumaroyltormentic Acid) Isolated From Aronia Extracts Inhibits Breast Cancer Stem Cell Formation through Downregulation of c-Myc Protein by Choi, Hack Sun, Kim, Su-Lim, Kim, Ji-Hyang, Deng, Hong-Yuan, Yun, Bong-Sik, Lee, Dong-Sun

“…Cancer stem cells (CSCs) are drug-resistant and radiation-resistant cancer cells that are responsible for tumor progression and maintenance, cancer recurrence,…”
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6-Methoxymellein Isolated from Carrot ( Daucus carota L.) Targets Breast Cancer Stem Cells by Regulating NF-κB Signaling by Liu, Ren, Choi, Hack Sun, Kim, Su-Lim, Kim, Ji-Hyang, Yun, Bong-Sik, Lee, Dong-Sun

“…The presence of breast cancer stem cells (BCSCs) induces the aggressive progression and recurrence of breast cancer. These cells are drug resistant, have the…”
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Catechol derived from aronia juice through lactic acid bacteria fermentation inhibits breast cancer stem cell formation via modulation Stat3/IL‐6 signaling pathway by Choi, Hack S., Kim, Ji‐Hyang, Kim, Su‐Lim, Deng, Hong‐Yuan, Lee, Doseung, Kim, Chang Sook, Yun, Bong‐Sik, Lee, Dong‐Sun

“…Cancer stem cells (CSCs) as a subpopulation of cancer cells are drug‐resistant and radiation‐resistant cancer cells to be responsible for tumor progress,…”
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Coriolic Acid (13-(S)-Hydroxy-9Z, 11E-octadecadienoic Acid) from Glasswort (Salicornia herbacea L.) Suppresses Breast Cancer Stem Cell through the Regulation of c-Myc by Ko, Yu-Chan, Choi, Hack Sun, Kim, Ji-Hyang, Kim, Su-Lim, Yun, Bong-Sik, Lee, Dong-Sun

“…Cancer stem cells have certain characteristics, such as self-renewal, differentiation, and drug resistance, which are related to tumor progression,…”
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The FDA-Approved Anti-Asthma Medicine Ciclesonide Inhibits Lung Cancer Stem Cells through Hedgehog Signaling-Mediated SOX2 Regulation by Choi, Hack Sun, Kim, Su-Lim, Kim, Ji-Hyang, Lee, Dong-Sun

“…Ciclesonide is an FDA-approved glucocorticoid (GC) used to treat asthma and allergic rhinitis. However, its effects on cancer and cancer stem cells (CSCs) are…”
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Inhibitory Effects of Tangeretin, A Citrus Peel-Derived Flavonoid, on Breast Cancer Stem Cell Formation through Suppression of Stat3 Signaling by Ko, Yu-Chan, Choi, Hack Sun, Liu, Ren, Kim, Ji-Hyang, Kim, Su-Lim, Yun, Bong-Sik, Lee, Dong-Sun

“…Breast cancer stem cells (BCSCs) are responsible for tumor chemoresistance and recurrence. Targeting CSCs using natural compounds is a novel approach for…”
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The Antiasthma Medication Ciclesonide Suppresses Breast Cancer Stem Cells through Inhibition of the Glucocorticoid Receptor Signaling-Dependent YAP Pathway by Kim, Su-Lim, Choi, Hack Sun, Kim, Ji-Hyang, Lee, Dong-Sun

“…Ciclesonide is an FDA-approved glucocorticoid used to treat asthma and allergic rhinitis. However, whether it has anticancer and anti-cancer stem cell (CSC)…”
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The PAK1-Stat3 Signaling Pathway Activates IL-6 Gene Transcription and Human Breast Cancer Stem Cell Formation by Kim, Ji-Hyang, Choi, Hack Sun, Kim, Su-Lim, Lee, Dong-Sun

“…Cancer stem cells (CSCs) have unique properties, including self-renewal, differentiation, and chemoresistance. In this study, we found that p21-activated…”
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Betavulgarin Isolated from Sugar Beet ( Beta vulgaris ) Suppresses Breast Cancer Stem Cells through Stat3 Signaling by Liu, Ren, Choi, Hack Sun, Zhen, Xing, Kim, Su-Lim, Kim, Ji-Hyang, Ko, Yu-Chan, Yun, Bong-Sik, Lee, Dong-Sun

“…Breast cancer is a major health problem that affects lives worldwide. Breast cancer stem cells (BCSCs) are small subpopulations of cells with capacities for…”
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Genetic Polymorphisms in miR-604A>G, miR-938G>A, miR-1302-3C>T and the Risk of Idiopathic Recurrent Pregnancy Loss by Cho, Sung-Hwan, Kim, Ji-Hyang, An, Hui-Jeong, Kim, Young-Ran, Ahn, Eun-Hee, Lee, Jung-Ryeol, Kim, Jung-Oh, Ko, Jung-Jae, Kim, Nam-Keun

“…The purpose of this study was to investigate whether polymorphisms in five microRNAs (miRNAs), miR-604A>G, miR-608C>G, 631I/D, miR-938G>A, and miR-1302-3C>T,…”
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Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer Stem Cell Formation by Choi, Hack Sun, Kim, Ji-Hyang, Kim, Su-Lim, Lee, Dong-Sun

“…Breast cancer stem cells (BCSCs) are tumor-initiating cells that possess the capacity for self-renewal. Cancer stem cells (CSCs) are responsible for poor…”
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Plant Volatile, Phenylacetaldehyde Targets Breast Cancer Stem Cell by Induction of ROS and Regulation of Stat3 Signal by Choi, Hack Sun, Kim, Su-Lim, Kim, Ji-Hyang, Ko, Yu-Chan, Lee, Dong-Sun

“…Cancer stem cells (CSCs) are undifferentiated cells that give rise to tumor and resistance to chemotherapy. This study reports that phenylacetaldehyde (PAA), a…”
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Caudatin Isolated from Cynanchum auriculatum Inhibits Breast Cancer Stem Cell Formation via a GR/YAP Signaling by Zhen, Xing, Choi, Hack Sun, Kim, Ji-Hyang, Kim, Su-Lim, Liu, Ren, Ko, Yu-Chan, Yun, Bong-Sik, Lee, Dong-Sun

“…In the complex tumor microenvironment, cancer stem cells (CSCs), a rare population of cells, are responsible for malignant tumor initiation, metastasis, drug…”
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Association of Polymorphisms in FSHR , INHA , ESR1 , and BMP15 with Recurrent Implantation Failure by Ko, Eun-Ju, Shin, Ji-Eun, Lee, Jung-Yong, Ryu, Chang-Soo, Hwang, Ji-Young, Kim, Young-Ran, Ahn, Eun-Hee, Kim, Ji-Hyang, Kim, Nam-Keun

“…Recurrent implantation failure (RIF) refers to two or more unsuccessful in vitro fertilization embryo transfers in the same individual. Embryonic…”
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Machilin D, a Lignin Derived from Saururus chinensis, Suppresses Breast Cancer Stem Cells and Inhibits NF-κB Signaling by Zhen, Xing, Choi, Hack Sun, Kim, Ji-Hyang, Kim, Su-Lim, Liu, Ren, Yun, Bong-Sik, Lee, Dong-Sun

“…Cancer stem cells are responsible for breast cancer initiation, metastasis, and relapse. Targeting breast cancer stem cells (BCSCs) using phytochemicals is a…”
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Association Study between Mucin 4 ( MUC4 ) Polymorphisms and Idiopathic Recurrent Pregnancy Loss in a Korean Population by Kim, Ji-Hyang, Park, Han-Sung, Lee, Jeong-Yong, Ko, Eun-Ju, Kim, Young-Ran, Cho, Hee-Young, Lee, Woo-Sik, Ahn, Eun-Hee, Kim, Nam-Keun

“…Recurrent pregnancy loss (RPL) is the loss of two or more consecutive pregnancies before 20 weeks of gestational age. Our study investigated whether mucin 4…”
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Genetic Polymorphisms in the 3'-Untranslated Regions of SMAD5, FN3KRP , and RUNX-1 Are Associated with Recurrent Pregnancy Loss by Kwon, Min-Jung, Kim, Ji-Hyang, Lee, Jeong-Yong, Ko, Eun-Ju, Park, Hyeon-Woo, Shin, Ji-Eun, Ahn, Eun-Hee, Kim, Nam-Keun

“…Recurrent pregnancy loss (RPL) is typically defined as two or more consecutive pregnancy losses prior to 20 weeks of gestation. Although the causes of…”
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Genetic Variations miR-10aA>T, miR-30cA>G, miR-181aT>C, and miR-499bA>G and the Risk of Recurrent Pregnancy Loss in Korean Women by An, Hui-Jeong, Cho, Sung-Hwan, Park, Han-Sung, Kim, Ji-Hyang, Kim, Young-Ran, Lee, Woo-Sik, Lee, Jung-Ryeol, Joo, Seong-Soo, Ahn, Eun-Hee, Kim, Nam-Keun

“…This study investigated the genetic association between recurrent pregnancy loss (RPL) and microRNA (miRNA) polymorphisms in miR-10aA>T, miR-30cA>G,…”
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