Search Results - "Kim, Ji Duck"

A first-in-human, double-blind, placebo-controlled, randomized, dose escalation study of DWP05195, a novel TRPV1 antagonist, in healthy volunteers by Lee, Jieon, Kim, Bo-Hyung, Yu, Kyung-Sang, Kim, Hee Sun, Kim, Ji Duck, Cho, Joo-Youn, Lee, SeungHwan, Gu, Namyi

“…DWP05195 is a transient receptor potential vanilloid 1 (TRPV1) antagonist developed for managing pain. The purpose of this study was to evaluate the…”
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Mechanism Studies on the CSI Reaction with Allyl Ethers by Varying p-Substituent by Jung, Young-Hoon, Kim, Ji-Duck

“…We examined the effect of p-substituents in p-substituted cinnamyl methyl ethers and 1-(p-substituted phenyl)allyl methyl ethers with CSI, and confirmed that…”
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A concise synthesis of (−)-cytoxazone and (−)-4- epi-cytoxazone using chlorosulfonyl isocyanate by Kim, In Su, Kim, Ji Duck, Ryu, Chae Baek, Zee, Ok Pyo, Jung, Young Hoon

“…A concise synthesis of (−)-cytoxazone and its stereoisomer (−)-4- epi-cytoxazone, novel cytokine modulators, has been accomplished each in six steps from…”
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Diastereoselective Synthesis of Unsaturated 1,4-Amino Alcohols as a Biologically Important Moiety by Jung Young Hoon, Kim Ji Duck

“…chial allylic ethers with a hydroxyl group attached to the $\pi-system$ and chlorosulfonyl isocyanate. The enantioselectivity of the CSI reaction with the…”
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One-pot Synthesis of Cinnamylamines with Various Protecting Groups from Cinnamyl Ethers by Jung, Young-Hoon, Kim, Ji-Duck

“…The reaction of various alkyl cinnamyl ethers with CSI afforded the corresponding cinnamylamines with various protecting groups, such as -NHMoc, -NHiPoc,…”
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Deprotection of benzyl and p-methoxybenzyl ethers by chlorosulfonyl isocyanate–sodium hydroxide by Kim, Ji Duck, Han, Gyoonhee, Zee, Ok Pyo, Jung, Young Hoon

“…CSI–NaOH procedure provided a new and mild methodology for the deprotection of benzyl and p-methoxybenzyl ethers without affecting the other functional groups…”
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Diastereoselective synthesis of unsaturated 1,4-amino alcohols as a biologically important moiety by Jung, Young Hoon, Kim, Ji Duck

“…The diastereoselective synthesis of unsaturated 1.4-amino alcohols can be achieved using chial allylic ethers with a hydroxyl group attached to the pi-system…”
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Mechanism studies on the CSI reaction with allyl ethers by varying p-substituent by Jung, Young Hoon, Kim, Ji Duck

“…We examined the effect of p-substituents in p-substituted cinnamyl methyl ethers and 1-(p-substituted phenyl)allyl methyl ethers with CSI, and confirmed that…”
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Regioselective and Diastereoselective Allylic Amination Using Chlorosulfonyl Isocyanate. A Novel Asymmetric Synthesis of Unsaturated Aromatic 1,2-Amino Alcohols by Kim, Ji Duck, Zee, Ok Pyo, Jung, Young Hoon

“…The diastereoselective synthesis of unsaturated aromatic 1,2-amino alcohols can be achieved on an epimeric mixture of optically active allylic ethers having a…”
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A first-in-human, double-blind, placebo-controlled, randomized, dose escalation study of DWP05I95, a novel TRPVI antagonist, in healthy volunteers by Lee, Jieon, Kim, Bo-Hyung, Yu, Kyung-Sang, Kim, Hee Sun, Kim, Ji Duck, Cho, Joo-Youn, Lee, SeungHwan, Gu, Namyi

“…Objectives: DWP05195 is a transient receptor potential vanilloid 1 (TRPV1) antagonist developed for managing pain. The purpose of this study was to evaluate…”
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Regioselective and Diastereoselective Amination with Use of Chlorosulfonyl Isocyanate:  A Short and Efficient Synthesis of (−)-Cytoxazone by Kim, Ji Duck, Kim, In Su, Jin, Cheng Hua, Zee, Ok Pyo, Jung, Young Hoon

“…The total synthesis of (−)-cytoxazone 1 was achieved in six linear steps (34% overall yield) from p-anisaldehyde. The key steps in this route are the…”
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Diastereoselective synthesis of unsaturated 1,2-amino alcohols from α-hydroxy allyl ethers using chlorosulfonyl isocyanate by Kim, Ji Duck, Kim, In Soo, Hua, Jin Cheng, Zee, Ok Pyo, Jung, Young Hoon

“…Diastereoselective synthesis of unsaturated 1,2-amino alcohols was achieved from a highly diastereoselective allylic amination reaction of α-hydroxy allyl…”
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Mechanism studies on the csi reaction with allyl ethers by varyingp-substituent by Jung, Young Hoon, Kim, Ji Duck

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Study of the stability of carbocations by chlorosulfonyl isocyanate reaction with ethers by Kim, Ji Duck, Han, Gyoonhee, Jeong, Lak Shin, Park, Hyun-Ju, Zee, Ok Pyo, Jung, Young Hoon

“…The stability order of various alkyl, allyl, and benzyl carbocations was investigated using the novel technique for comparing the stability of carbocations in…”
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Synthesis of N-protected allylic amines from allyl ethers by Kim, Ji Duck, Lee, Min Hee, Han, Gyoonhee, Park, Hyunju, Zee, Ok Pyo, Jung, Young Hoon

“…A synthetic method for N-protected allylic amines from allyl ethers using chlorosulfonyl isocyanate (CSI) is presented. The reaction of 4-phenylbut-2-enyl…”
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One-pot synthesis of cinnamylamines with various protecting groups from cinnamyl ethers by Jung, Y H, Kim, J D

“…The reaction of various alkyl cinnamyl ethers with CSI afforded the corresponding cinnamylamines with various protecting groups, such as -NHMoc, -NHiPoc,…”
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