Search Results - "Kim, Jane C."

The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats by Kim, Jane C, Harris, Samantha T, Dinter, Teresa, Shah, Kartik A, Mirkin, Sergei M

“…A newly developed assay in yeast reveals that large-scale expansions of trinucleotide repeats can occur in a single step, rather than through several…”
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Isolation and characterization of human periodontal ligament (PDL) stem cells (PDLSCs) from the inflamed PDL tissue: in vitro and in vivo evaluations by Park, Jung-Chul, Kim, Jeong-Min, Jung, Im-Hee, Kim, Jane C., Choi, Seong-Ho, Cho, Kyoo-Sung, Kim, Chang-Sung

“…Park J‐C, Kim J‐M, Jung I‐H, Kim JC, Choi S‐H, Cho K‐S, Kim C‐S. Isolation and characterization of human periodontal ligament (PDL) stem cells (PDLSCs) from…”
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Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability by Tsutakawa, Susan E., Thompson, Mark J., Arvai, Andrew S., Neil, Alexander J., Shaw, Steven J., Algasaier, Sana I., Kim, Jane C., Finger, L. David, Jardine, Emma, Gotham, Victoria J.B., Sarker, Altaf H., Her, Mai Z., Rashid, Fahad, Hamdan, Samir M., Mirkin, Sergei M., Grasby, Jane A., Tainer, John A.

“…DNA replication and repair enzyme Flap Endonuclease 1 (FEN1) is vital for genome integrity, and FEN1 mutations arise in multiple cancers. FEN1 precisely…”
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Genome rearrangements caused by interstitial telomeric sequences in yeast by Aksenova, Anna Y., Greenwell, Patricia W., Dominska, Margaret, Shishkin, Alexander A., Kim, Jane C., Petes, Thomas D., Mirkin, Sergei M.

“…Interstitial telomeric sequences (ITSs) are present in many eukaryotic genomes and are linked to genome instabilities and disease in humans. The mechanisms…”
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Putting the Brakes on Huntington Disease in a Mouse Experimental Model by Kim, Jane C, Mirkin, Sergei M

“…  [...]candidate gene analysis uncovered a surprising role of the mismatch repair (MMR) complex MutS[Beta] in promoting rather than protecting against CAG…”
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Analysis of a Drosophila amplicon in follicle cells highlights the diversity of metazoan replication origins by Kim, Jane C, Orr-Weaver, Terry L

“…To investigate the properties of metazoan replication origins, recent studies in cell culture have adopted the strategy of identifying origins using…”
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The balancing act of DNA repeat expansions by Kim, Jane C, Mirkin, Sergei M

“…Expansions of microsatellite DNA repeats contribute to the inheritance of nearly 30 developmental and neurological disorders. Significant progress has been…”
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Precarious maintenance of simple DNA repeats in eukaryotes by Neil, Alexander J., Kim, Jane C., Mirkin, Sergei M.

“…In this review, we discuss how two evolutionarily conserved pathways at the interface of DNA replication and repair, template switching and break‐induced…”
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Massive contractions of myotonic dystrophy type 2-associated CCTG tetranucleotide repeats occur via double-strand break repair with distinct requirements for DNA helicases by Papp, David, Hernandez, Luis A, Mai, Theresa A, Haanen, Terrance J, O’Donnell, Meghan A, Duran, Ariel T, Hernandez, Sophia M, Narvanto, Jenni E, Arguello, Berenice, Onwukwe, Marvin O, Mirkin, Sergei M, Kim, Jane C

“…Abstract Myotonic dystrophy type 2 (DM2) is a genetic disease caused by expanded CCTG DNA repeats in the first intron of CNBP. The number of CCTG repeats in…”
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Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression by Kim, Jane C, Nordman, Jared, Xie, Fang, Kashevsky, Helena, Eng, Thomas, Li, Sharon, MacAlpine, David M, Orr-Weaver, Terry L

“…In metazoans, how replication origins are specified and subsequently activated is not well understood. Drosophila amplicons in follicle cells (DAFCs) are…”
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Acquisition of human alveolar bone-derived stromal cells using minimally irrigated implant osteotomy: in vitro and in vivo evaluations by Park, Jung-Chul, Kim, Jane C., Kim, Yong-Tae, Choi, Seong-Ho, Cho, Kyoo-Sung, Im, Gun-Il, Kim, Byung-Soo, Kim, Chang-Sung

“…Objectives Implant osteotomy yields a substantial amount of bone in the form of bone chips entrapped within drill flutes, and can provide a promising cell…”
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Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability by Tsutakawa, Susan E, Thompson, Mark J, Arvai, Andrew S, Neil, Alexander J, Shaw, Steven J, Algasaier, Sana I, Kim, Jane C, Finger, L David, Jardine, Emma, Gotham, Victoria J B, Sarker, Altaf H, Her, Mai Z, Rashid, Fahad, Hamdan, Samir M, Mirkin, Sergei M, Grasby, Jane A, Tainer, John A

“…[This corrects the article DOI: 10.1038/ncomms15855.]…”
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Novel application of human periodontal ligament stem cells and water-soluble chitin for collagen tissue regeneration: in vitro and in vivo investigations by Jung, Im Hee, Park, Jung Chul, Kim, Jane C, Jeon, Dong Won, Choi, Seong Ho, Cho, Kyoo Sung, Im, Gun Il, Kim, Byung Soo, Kim, Chang Sung

“…Human periodontal ligament stem cells (hPDLSCs) have been proposed as an alternative to conventional cosmetic fillers because they display an innate ability to…”
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Putting the Brakes on Huntington Disease in a Mouse Experimental Model: e1005409 by Kim, Jane C, Mirkin, Sergei M

“…[...]candidate gene analysis uncovered a surprising role of the mismatch repair (MMR) complex MutS[Beta] in promoting rather than protecting against CAG repeat…”
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The role of break-induced replication in large-scale expansions of (CAG) sub(n)/(CTG) sub(n) repeats by Kim, Jane C, Harris, Samantha T, Dinter, Teresa, Shah, Kartik A, Mirkin, Sergei M

“…Expansions of (CAG) sub(n)/(CTG) sub(n) trinucleotide repeats are responsible for over a dozen neuromuscular and neurodegenerative disorders. Large-scale…”
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The role of break-induced replication in large-scale expansions of n repeats by Kim, Jane C, Harris, Samantha T, Dinter, Teresa, Shah, Kartik A, Mirkin, Sergei M

“…Expansions of (CAG)[sub.n]/(CTG)[sub.n] trinucleotide repeats are responsible for over a dozen neuromuscular and neurodegenerative disorders. Large-scale…”
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Regulation of origin activation during Drosophila follicle cell gene amplification by Hua, Brian, Li, Sharon, Kim, Jane C., Orr‐Weaver, Terry L.

“…Abstract only We are utilizing the Drosophila follicle cell gene amplification system to better understand the mechanisms of DNA replication origin activation…”
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Correction: Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability by Tsutakawa, Susan E., Thompson, Mark J., Arvai, Andrew S., Neil, Alexander J., Shaw, Steven J., Algasaier, Sana I., Kim, Jane C., Finger, L. David, Jardine, Emma, Gotham, Victoria J. B., Sarker, Altaf H., Her, Mai Z., Rashid, Fahad, Hamdan, Samir M., Mirkin, Sergei M., Grasby, Jane A., Tainer, John A.

“…Nature Communications 8 Article number: 15855 (2017); Published: 27 June 2017; Updated: 7 August 2017 The financial support for this Article was not fully…”
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Isolation and characterization of human periodontal ligament (PDL) stem cells (PDLSCs) from the inflamed PDL tissue: in vitro and in vivo evaluations: Stem cells from inflamed PDL by Park, Jung-Chul, Kim, Jeong-Min, Jung, Im-Hee, Kim, Jane C., Choi, Seong-Ho, Cho, Kyoo-Sung, Kim, Chang-Sung

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