Search Results - "Kim, In Kyeom"
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1
A Dual Role of Lipocalin 2 in the Apoptosis and Deramification of Activated Microglia
Published in Journal of Immunology (01-09-2007)“…Activated microglia are thought to undergo apoptosis as a self-regulatory mechanism. To better understand molecular mechanisms of the microglial apoptosis,…”
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2
Cystic Lymphangioma of the Abdominal Wall in Childhood: A Report of Two Cases Focused on Radiologic Findings
Published in Iranian journal of radiology (01-04-2017)“…A cystic lymphangioma is a rare benign tumor of the lymphatic tissue that mostly affects the head and neck, and usually manifests during childhood. Cystic…”
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3
Isoflavone attenuates vascular contraction through inhibition of the RhoA/Rho-kinase signaling pathway
Published in The Journal of pharmacology and experimental therapeutics (01-09-2008)“…Isoflavones decrease blood pressure, improve lipid profiles, and restore vascular function. We hypothesized that isoflavone attenuates vascular contraction by…”
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4
Regulation of Toll-like receptor 4 expression and its signaling by hypoxia in cultured microglia
Published in Journal of neuroscience research (01-07-2007)“…Hypoxia is an important biological signal that regulates a wide variety of physiological responses. At the same time, hypoxia is involved in multiple…”
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5
Gallotannin Isolated from Euphorbia Species, 1,2,6-Tri-O-galloyl-β-D-allose, Decreases Nitric Oxide Production through Inhibition of Nuclear Factor-κ>B and Downstream Inducible Nitric Oxide Synthase Expression in Macrophages
Published in Biological & pharmaceutical bulletin (01-06-2009)“…Gallotannins are plant secondary metabolites and are widely included to polyphenolic compounds. Gallotannins are water-soluble polyphenols with wide-ranging…”
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6
Effects of 3′,4′-dihydroxyflavonol on vascular contractions of rat aortic rings
Published in Clinical and experimental pharmacology & physiology (01-08-2010)“…Summary 1. 3′,4′‐Dihydroxyflavonol (DiOHF) is an effective vasodilator with anti‐oxidant activity. The aim of the present study was to elucidate the effects of…”
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7
Effects of gomisin A on vascular contraction in rat aortic rings
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-01-2011)“…Gomisin A (GA) is an active ingredient of the fruits of Schisandra chinensis which has been widely used as a tonic in traditional Korean medicine. GA induces…”
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8
Induction of microglial apoptosis by corticotropin‐releasing hormone
Published in Journal of neurochemistry (01-08-2006)“…Neuropeptides are short‐chain peptides found in brain tissue, some of which function as neurotransmitters and others as hormones. Neuropeptides may directly or…”
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9
Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes
Published in Vascular pharmacology (01-09-2015)“…Abstract Inflammation and fibrosis are implicated in the pathogenesis of hypertensive kidney damage. We previously demonstrated that a nonspecific histone…”
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10
Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor Through Its Acetylation and Prevents Development of Hypertension
Published in Circulation research (29-03-2013)“…RATIONALE:Inhibition of histone deacetylases (HDACs) results in attenuated development of hypertension in deoxycorticosterone acetate–induced hypertensive rats…”
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11
Combined oral contraceptive-induced hypertension is accompanied by endothelial dysfunction and upregulated intrarenal angiotensin II type 1 receptor gene expression
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2016)“…Combined oral contraceptive (COC) use is associated with increased risk of developing hypertension. Activation of the intrarenal renin-angiotensin system (RAS)…”
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12
Histone deacetylase inhibition attenuates hepatic steatosis in rats with experimental Cushing’s syndrome
Published in The Korean journal of physiology & pharmacology (01-01-2018)“…Cushing's syndrome (CS) is a collection of symptoms caused by prolonged exposure to excess cortisol. Chronically elevated glucocorticoid (GC) levels contribute…”
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13
Tissue-Specific Upregulation of Angiotensin-Converting Enzyme 1 in Spontaneously Hypertensive Rats Through Histone Code Modifications
Published in Hypertension (Dallas, Tex. 1979) (01-03-2012)“…The renin-angiotensin system has been implicated in the development of hypertension and damages several organs. The expressions of the components of a local…”
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14
Combined oral contraceptive and nitric oxide synthesis inhibition synergistically causes cardiac hypertrophy and exacerbates insulin resistance in female rats
Published in Environmental toxicology and pharmacology (01-06-2017)“…Highlights • COC treatment or NO deficiency induces high blood pressure and cardiometabolic disturbances. • COC treatment or NO deficiency does not result in…”
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15
Expression of Na -K -2Cl Cotransporter 1 Is Epigenetically Regulated During Postnatal Development of Hypertension
Published in American journal of hypertension (01-12-2011)“…Background The expression of Na+-K+-2Cl− cotransporter 1 (NKCC1) is upregulated in spontaneously hypertensive rat (SHR). We investigated whether expression of…”
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Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder
Published in Archives of physiology and biochemistry (01-02-2017)“…Context: Clinical studies have shown that combined oral contraceptive (COC) use is associated with cardiometabolic disturbances. Elevated renin-angiotensin…”
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17
Upregulation of PBR mRNA expression in human neuroblastoma cells by flavonoids
Published in Phytomedicine (Stuttgart) (01-02-2007)“…To investigate the putative mediation of peripheral benzodiazepine receptor (PBR) in the cytotoxicity of flavonoids, in this study, modulatory effects of…”
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18
The effect of DA-9701 on 5-hydroxytryptamine-induced contraction of feline esophageal smooth muscle cells
Published in Molecules (Basel, Switzerland) (22-04-2014)“…Serotonin, or 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter found in blood platelets, the gastrointestinal (GI) tract, and the central nervous…”
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Glucosamine increases vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aorta
Published in BMB reports (30-06-2011)“…Diabetes is a well-known independent risk factor for vascular disease. However, its underlying mechanism remains unclear. It has been reported that increased…”
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Upregulation of the Na(+)-K(+)-2Cl(-) cotransporter 1 via histone modification in the aortas of angiotensin II-induced hypertensive rats
Published in Hypertension research (01-08-2012)“…The Na(+)-K(+)-2Cl(-) cotransporter 1 (NKCC1) is upregulated in diverse models of hypertension. We hypothesized that NKCC1 is upregulated via histone…”
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