Search Results - "Kim, Hyuk Soon"
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IL-27-induced PD-L1highSca-1+ innate lymphoid cells suppress contact hypersensitivity in an IL-10-dependent manner
Published in Experimental & molecular medicine (01-03-2024)“…Innate lymphoid cells (ILCs) play an important role in maintaining tissue homeostasis and various inflammatory responses. ILCs are typically classified into…”
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2
DJ-1 regulates mast cell activation and IgE-mediated allergic responses
Published in Journal of allergy and clinical immunology (01-06-2013)“…Background DJ-1 is an antioxidant protein known to reduce levels of reactive oxygen species (ROS), but its presence or function in mast cells and allergic…”
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Oral Administration of Curcumin Suppresses Production of Matrix Metalloproteinase (MMP)-1 and MMP-3 to Ameliorate Collagen-Induced Arthritis: Inhibition of the PKCδ/JNK/c-Jun Pathway
Published in Journal of Pharmacological Sciences (2009)“…We investigated whether oral administration of curcumin suppressed type II collagen–induced arthritis (CIA) in mice and its effect and mechanism on matrix…”
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4
Dual Relationship Between Stromal Cells and Immune Cells in the Tumor Microenvironment
Published in Frontiers in immunology (06-04-2022)“…The tumor microenvironment (TME) plays a critical role in tumorigenesis and is comprised of different components, including tumor cells, stromal cells, and…”
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5
Effects of the immunoglobulin/histamine complex on panic disorder concurrent with chronic spontaneous urticaria: a case report
Published in Journal of medical case reports (28-07-2023)“…Panic disorder and panic attacks are two of the most common problems in psychiatry. A psychoimmunological correlation between allergic diseases and panic…”
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6
Yam-derived exosome-like nanovesicles stimulate osteoblast formation and prevent osteoporosis in mice
Published in Journal of controlled release (01-03-2023)“…Plants-releasing exosome-like nanovesicles (PENs) contain miRNA, bioactive lipids, mRNAs, and proteins to exert antioxidant, anti-inflammatory, and…”
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Entinostat, a histone deacetylase inhibitor, increases the population of IL-10 + regulatory B cells to suppress contact hypersensitivity
Published in BMB reports (31-10-2021)“…IL-10 + regulatory B (Breg) cells play a vital role in regulating the immune responses in experimental autoimmune encephalomyelitis, colitis, and contact…”
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Induction of remission in chronic urticaria by immunotherapy using immunoglobulin/histamine complex (Histobulin™): a case report
Published in Allergy, asthma, and clinical immunology (12-11-2021)“…Abstract Background Symptom control is a major concern in chronic urticaria. Histobulin™ is a histamine/immunoglobulin complex that has been approved for…”
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Treatment of primary eosinophilic colitis using immunoglobulin/histamine complex
Published in Clinical case reports (01-01-2023)“…Primary eosinophilic colitis (PEC) is a primary eosinophilic gastrointestinal disorder, and immunoglobulin/histamine complex (IHC) may be an effective…”
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IL-10+ regulatory B cells mitigate atopic dermatitis by suppressing eosinophil activation
Published in Scientific reports (06-08-2024)“…Atopic dermatitis (AD) presents significant therapeutic challenges due to its poorly understood etiology. Eosinophilia, a hallmark of allergic inflammation, is…”
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11
DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation
Published in Nature communications (15-11-2017)“…Receptor activator of NF-kB ligand (RANKL) generates intracellular reactive oxygen species (ROS), which increase RANKL-mediated signaling in osteoclast (OC)…”
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12
Immunotherapy using Histobulin™ in psoriasis: A case report
Published in Clinical case reports (01-05-2022)“…There is no cure for psoriasis. A psoriasis patient was treated with Histobulin™. The patient's clinical symptoms and signs disappeared after the eighth…”
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13
Hexosamine Biosynthetic Pathway-Derived O-GlcNAcylation Is Critical for RANKL-Mediated Osteoclast Differentiation
Published in International journal of molecular sciences (18-08-2021)“…O-linked-N-acetylglucosaminylation (O-GlcNAcylation) performed by O-GlcNAc transferase (OGT) is a nutrient-responsive post-translational modification (PTM) via…”
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14
Natural Products as a Novel Therapeutic Strategy for NLRP3 Inflammasome-Mediated Gout
Published in Frontiers in pharmacology (16-03-2022)“…Gout is the most common form of inflammatory arthritis. It occurs when monosodium urate crystals (MSU) are deposited within joints due to hyperuricemia and…”
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Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice
Published in Biomolecules & therapeutics (01-09-2020)“…Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity…”
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Strategies for Overcoming Immune Evasion in Bladder Cancer
Published in International journal of molecular sciences (01-03-2024)“…Tumors intricately shape a highly immunosuppressive microenvironment, hampering effective antitumor immune responses through diverse mechanisms. Consequently,…”
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A Novel Imidazo[1,5-b]isoquinolinone Derivative, U63A05, Inhibits Syk Activation in Mast Cells to Suppress IgE-Mediated Anaphylaxis in Mice
Published in Journal of Pharmacological Sciences (2011)“…Mast cells play a pivotal role in IgE-mediated allergic responses. Development of specific inhibitors against FcεRI-associated proximal signaling molecules in…”
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Embryonic-stem-cell-derived mesenchymal stem cells relieve experimental contact urticaria by regulating the functions of mast cells and T cells
Published in Scientific reports (20-12-2023)“…Contact urticaria (CU) is an inflammatory skin disorder triggered by specific substances upon skin contact, leading to immediate acute or chronic…”
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JQ1, a BET inhibitor, controls TLR4-induced IL-10 production in regulatory B cells by BRD4-NF-κB axis
Published in BMB reports (31-12-2017)“…Regulatory B cells, also well-known as IL-10-producing B cells, play a role in the suppression of inflammatory responses. However, the epigenetic modulation of…”
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Polysaccharide isolated from Aloe vera gel suppresses ovalbumin-induced food allergy through inhibition of Th2 immunity in mice
Published in Biomedicine & pharmacotherapy (01-05-2018)“…[Display omitted] •Processed Aloe vera gel (PAG) suppresses food allergy in mice.•PAG inhibits Th2 immune responses in mice.•PAG increases the production of…”
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