Search Results - "Kim, Hyuk Soon"

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  1. 1

    IL-27-induced PD-L1highSca-1+ innate lymphoid cells suppress contact hypersensitivity in an IL-10-dependent manner by Min, Keun Young, Kim, Do-Kyun, Jo, Min Geun, Choi, min Yeong, Lee, Dajeong, Park, Jeong Won, Park, Young-Jun, Chung, Yeonseok, Kim, Young Mi, Park, Yeong-Min, Kim, Hyuk Soon, Choi, Wahn Soo

    Published in Experimental & molecular medicine (01-03-2024)
    “…Innate lymphoid cells (ILCs) play an important role in maintaining tissue homeostasis and various inflammatory responses. ILCs are typically classified into…”
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  2. 2

    DJ-1 regulates mast cell activation and IgE-mediated allergic responses by Kim, Do Kyun, PhD, Kim, Hyuk Soon, MS, Kim, A-Ram, MS, Kim, Ji Hyung, BS, Kim, Bokyung, PhD, Noh, Geunwoong, MD, PhD, Kim, Hyung Sik, PhD, Beaven, Michael A., PhD, Kim, Young Mi, PhD, Choi, Wahn Soo, PhD

    Published in Journal of allergy and clinical immunology (01-06-2013)
    “…Background DJ-1 is an antioxidant protein known to reduce levels of reactive oxygen species (ROS), but its presence or function in mast cells and allergic…”
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    Dual Relationship Between Stromal Cells and Immune Cells in the Tumor Microenvironment by Mun, Jeong-Yeon, Leem, Sun-Hee, Lee, Jun Ho, Kim, Hyuk Soon

    Published in Frontiers in immunology (06-04-2022)
    “…The tumor microenvironment (TME) plays a critical role in tumorigenesis and is comprised of different components, including tumor cells, stromal cells, and…”
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  5. 5

    Effects of the immunoglobulin/histamine complex on panic disorder concurrent with chronic spontaneous urticaria: a case report by Kim, Hyuk Soon, Noh, Geunwoong

    Published in Journal of medical case reports (28-07-2023)
    “…Panic disorder and panic attacks are two of the most common problems in psychiatry. A psychoimmunological correlation between allergic diseases and panic…”
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    Entinostat, a histone deacetylase inhibitor, increases the population of IL-10 + regulatory B cells to suppress contact hypersensitivity by Min, Keun Young, Lee, Min Bum, Hong, Seong Hwi, Lee, Dajeong, Jo, Min Geun, Lee, Ji Eon, Choi, Min Yeong, You, Jueng Soo, Kim, Young Mi, Park, Yeong Min, Kim, Hyuk Soon, Choi, Wahn Soo

    Published in BMB reports (31-10-2021)
    “…IL-10 + regulatory B (Breg) cells play a vital role in regulating the immune responses in experimental autoimmune encephalomyelitis, colitis, and contact…”
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  8. 8

    Induction of remission in chronic urticaria by immunotherapy using immunoglobulin/histamine complex (Histobulin™): a case report by Kim, Hyuk Soon, Noh, Geunwoong

    Published in Allergy, asthma, and clinical immunology (12-11-2021)
    “…Abstract Background Symptom control is a major concern in chronic urticaria. Histobulin™ is a histamine/immunoglobulin complex that has been approved for…”
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  9. 9

    Treatment of primary eosinophilic colitis using immunoglobulin/histamine complex by Kim, Hyuk Soon, Noh, Geunwoong

    Published in Clinical case reports (01-01-2023)
    “…Primary eosinophilic colitis (PEC) is a primary eosinophilic gastrointestinal disorder, and immunoglobulin/histamine complex (IHC) may be an effective…”
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  10. 10

    IL-10+ regulatory B cells mitigate atopic dermatitis by suppressing eosinophil activation by Lee, Dajeong, Jo, Min Geun, Min, Keun Young, Choi, Min Yeong, kim, Young Mi, Kim, Hyuk Soon, Choi, Wahn Soo

    Published in Scientific reports (06-08-2024)
    “…Atopic dermatitis (AD) presents significant therapeutic challenges due to its poorly understood etiology. Eosinophilia, a hallmark of allergic inflammation, is…”
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  11. 11

    DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation by Kim, Hyuk Soon, Nam, Seung Taek, Mun, Se Hwan, Lee, Sun-Kyeong, Kim, Hyun Woo, Park, Young Hwan, Kim, Bokyung, Won, Kyung-Jong, Kim, Hae-Rim, Park, Yeong-Min, Kim, Hyung Sik, Beaven, Michael A., Kim, Young Mi, Choi, Wahn Soo

    Published in Nature communications (15-11-2017)
    “…Receptor activator of NF-kB ligand (RANKL) generates intracellular reactive oxygen species (ROS), which increase RANKL-mediated signaling in osteoclast (OC)…”
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  12. 12

    Immunotherapy using Histobulin™ in psoriasis: A case report by Kim, Hyuk Soon, Noh, Geunwoong

    Published in Clinical case reports (01-05-2022)
    “…There is no cure for psoriasis. A psoriasis patient was treated with Histobulin™. The patient's clinical symptoms and signs disappeared after the eighth…”
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  13. 13

    Hexosamine Biosynthetic Pathway-Derived O-GlcNAcylation Is Critical for RANKL-Mediated Osteoclast Differentiation by Kim, Myoung Jun, Kim, Hyuk Soon, Lee, Sangyong, Min, Keun Young, Choi, Wahn Soo, You, Jueng Soo

    “…O-linked-N-acetylglucosaminylation (O-GlcNAcylation) performed by O-GlcNAc transferase (OGT) is a nutrient-responsive post-translational modification (PTM) via…”
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  14. 14

    Natural Products as a Novel Therapeutic Strategy for NLRP3 Inflammasome-Mediated Gout by Lee, Jun Ho, Kim, Hyuk Soon, Lee, Jun-Ho, Yang, Gabsik, Kim, Hong Jun

    Published in Frontiers in pharmacology (16-03-2022)
    “…Gout is the most common form of inflammatory arthritis. It occurs when monosodium urate crystals (MSU) are deposited within joints due to hyperuricemia and…”
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    Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice by Lee, Dajeong, Park, Young Hwan, Lee, Ji Eon, Kim, Hyuk Soon, Min, Keun Young, Jo, Min Geun, Kim, Hyung Sik, Choi, Wahn Soo, Kim, Young Mi

    Published in Biomolecules & therapeutics (01-09-2020)
    “…Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity…”
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    Strategies for Overcoming Immune Evasion in Bladder Cancer by Shin, Juhyun, Park, Jeong Won, Kim, Seon Young, Lee, Jun Ho, Choi, Wahn Soo, Kim, Hyuk Soon

    “…Tumors intricately shape a highly immunosuppressive microenvironment, hampering effective antitumor immune responses through diverse mechanisms. Consequently,…”
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  17. 17

    A Novel Imidazo[1,5-b]isoquinolinone Derivative, U63A05, Inhibits Syk Activation in Mast Cells to Suppress IgE-Mediated Anaphylaxis in Mice by Kim, Do Kyun, Lee, Jun Ho, Kim, Jie Wan, Kim, Hyuk Soon, Kim, A-Ram, Kim, Bo Kyung, Yi, Kyu Yang, Park, Hye-Jin, Park, Dong Ki, Choi, Wahn Soo

    “…Mast cells play a pivotal role in IgE-mediated allergic responses. Development of specific inhibitors against FcεRI-associated proximal signaling molecules in…”
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  18. 18

    Embryonic-stem-cell-derived mesenchymal stem cells relieve experimental contact urticaria by regulating the functions of mast cells and T cells by Hyun, Seung Yeun, Kim, Eun-Young, Kang, Minseong, Park, Jeong Won, Hong, Ki-Sung, Chung, Hyung-Min, Choi, Wahn Soo, Park, Se-Pill, Noh, Geunwoong, Kim, Hyuk Soon

    Published in Scientific reports (20-12-2023)
    “…Contact urticaria (CU) is an inflammatory skin disorder triggered by specific substances upon skin contact, leading to immediate acute or chronic…”
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    JQ1, a BET inhibitor, controls TLR4-induced IL-10 production in regulatory B cells by BRD4-NF-κB axis by Lee, Min Bum, Lee, Jun-Ho, Hong, Seong Hwi, You, Jueng Soo, Nam, Seung Taek, Kim, Hyun Woo, Park, Young Hwan, Lee, Dajeong, Min, Keun Young, Park, Yeong-Min, Kim, Young Mi, Kim, Hyuk Soon, Choi, Wahn Soo

    Published in BMB reports (31-12-2017)
    “…Regulatory B cells, also well-known as IL-10-producing B cells, play a role in the suppression of inflammatory responses. However, the epigenetic modulation of…”
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  20. 20

    Polysaccharide isolated from Aloe vera gel suppresses ovalbumin-induced food allergy through inhibition of Th2 immunity in mice by Lee, Dajeong, Kim, Hyuk Soon, Shin, Eunju, Do, Seon-Gil, Lee, Chong-Kil, Kim, Young Mi, Lee, Min Bum, Min, Keun Young, Koo, Jimo, Kim, Su Jeong, Nam, Seung Taek, Kim, Hyun Woo, Park, Young Hwan, Choi, Wahn Soo

    Published in Biomedicine & pharmacotherapy (01-05-2018)
    “…[Display omitted] •Processed Aloe vera gel (PAG) suppresses food allergy in mice.•PAG inhibits Th2 immune responses in mice.•PAG increases the production of…”
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