Search Results - "Kim, Hyoung June"
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A novel optical coherence tomography‐based in vitro method of anti‐aging skin analysis using 3D skin wrinkle mimics
Published in Skin research and technology (01-06-2023)“…Background Wrinkles represent a characteristic symptom of skin aging. In recent years, various studies have focused on their prevention and/or cure. However,…”
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Transcriptome‐wide analysis reveals GYG2 as a mitochondria‐related aging biomarker in human subcutaneous adipose tissue
Published in Aging cell (01-02-2024)“…Subcutaneous adipose tissue (SAT), a vital energy reservoir and endocrine organ for maintaining systemic glucose, lipid, and energy homeostasis, undergoes…”
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3
β-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling
Published in Scientific reports (15-12-2023)“…Solar ultraviolet B (UVB) radiation triggers excessive inflammation, disrupting the epidermal barrier, and can eventually cause skin cancer. A previous study…”
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Tyrosinase-Targeting Gallacetophenone Inhibits Melanogenesis in Melanocytes and Human Skin-Equivalents
Published in International journal of molecular sciences (29-04-2020)“…Demands for safe depigmentation compounds are constantly increasing in the pharmaceutical and cosmetic industry, since the numerous relevant compounds reported…”
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A novel mineralocorticoid receptor antagonist, 7,3',4'-trihydroxyisoflavone improves skin barrier function impaired by endogenous or exogenous glucocorticoids
Published in Scientific reports (07-06-2021)“…Excess glucocorticoids (GCs) with either endogenous or exogenous origins deteriorate skin barrier function. GCs bind to mineralocorticoid and GC receptors (MRs…”
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6
Integrative analysis to explore the biological association between environmental skin diseases and ambient particulate matter
Published in Scientific reports (13-06-2022)“…Although numerous experimental studies have suggested a significant association between ambient particulate matter (PM) and respiratory damage, the etiological…”
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Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes
Published in International journal of molecular sciences (29-09-2022)“…Particulate matter 2.5 (PM2.5), an atmospheric pollutant with an aerodynamic diameter of <2.5 μm, can cause serious human health problems, including skin…”
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Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes
Published in Scientific reports (08-03-2019)“…Exposure to fine particulate matter (PM) with diameter <2.5 µm (PM2.5) causes epithelium injury and endothelial dysfunction. Primary cilia are sensory…”
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Glucose Exerts an Anti-Melanogenic Effect by Indirect Inactivation of Tyrosinase in Melanocytes and a Human Skin Equivalent
Published in International journal of molecular sciences (03-03-2020)“…Sugars are ubiquitous in organisms and well-known cosmetic ingredients for moisturizing skin with minimal side-effects. Glucose, a simple sugar used as an…”
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10
Melasolv induces melanosome autophagy to inhibit pigmentation in B16F1 cells
Published in PloS one (17-09-2020)“…The melanosome is a specialized membrane-bound organelle that is involved in melanin synthesis, storage, and transportation. In contrast to melanosome…”
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The natural phytochemical trans‐communic acid inhibits cellular senescence and pigmentation through FoxO3a activation
Published in Experimental dermatology (01-11-2019)“…Ageing is characterized by the accumulation of chronic and irreversible oxidative damage, chronic inflammation and organ dysfunction. To attenuate these…”
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3,4,5-Trimethoxycinnamate thymol ester inhibits melanogenesis in normal human melanocytes and 3D human epidermal equivalents via the PGC-1α-independent PPARγ partial agonism
Published in Journal of dermatological science (01-04-2022)“…•TCTE, an anti-melanogenic agent, increased adiponectin production.•TCTE acted as a PPARγ partial agonist.•A PPARγ antagonist attenuated the effect of TCTE on…”
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13
UVB-dependent inhibition of lipin-1 protects against proinflammatory responses in human keratinocytes
Published in Experimental & molecular medicine (01-02-2020)“…Lipin-1 is an Mg 2+ -dependent phosphatidate phosphatase (PAP1) that catalyzes a critical step in the synthesis of glycerophospholipids and is also a…”
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14
Violet light down-regulates the expression of specific differentiation markers through Rhodopsin in normal human epidermal keratinocytes
Published in PloS one (17-09-2013)“…Several recent reports have demonstrated that photoreceptors are expressed in human skin. The rod and cone photoreceptor-like proteins are expressed in human…”
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Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells
Published in Journal of ginseng research (01-05-2023)“…The human hair follicle undergoes cyclic phases—anagen, catagen, and telogen—throughout its lifetime. This cyclic transition has been studied as a target for…”
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16
S-nitrosylation of fatty acid synthase regulates its activity through dimerization[S]
Published in Journal of lipid research (01-04-2016)“…NO regulates a variety of physiological processes, including cell proliferation, differentiation, and inflammation. S-nitrosylation, a NO-mediated reversible…”
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Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion
Published in Journal of dermatological science (01-04-2014)“…Abstract Background Staphylococcus aureus ( S. aureus ) is found on the skin of approximately 90% of patients with atopic dermatitis and approximately 20% of…”
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TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
Published in Nature communications (19-01-2016)“…RAP80 localizes to sites of DNA insults to enhance the DNA-damage responses. Here we identify TRAIP/RNF206 as a novel RAP80-interacting protein and find that…”
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Primary Ciliogenesis by 2-Isopropylmalic Acid Prevents PM2.5-Induced Inflammatory Response and MMP-1 Activation in Human Dermal Fibroblasts and a 3-D-Skin Model
Published in International journal of molecular sciences (10-10-2021)“…Particulate matters (PMs) increase oxidative stress and inflammatory response in different tissues. PMs disrupt the formation of primary cilia in various skin…”
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Transcriptomic analysis of human dermal fibroblast cells reveals potential mechanisms underlying the protective effects of visible red light against damage from ultraviolet B light
Published in Journal of dermatological science (01-05-2019)“…•Pretreatment of visible red light diminished the UV-induced damage in NHDFs.•Transcriptomic analysis of red light-exposed NHDFs revealed UV-protective…”
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