Search Results - "Kim, Hyon Jeen"

Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity : Role of dendritic cells by KIM, Hyon-Jeen, BARAJAS, Berenice, MEIYING WANG, NEL, Andre E

“…Background The decrease in cellular immunity with aging is of considerable public health importance. Recent studies suggest that the redox equilibrium of…”
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Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: Implications for systemic disease and immunosenescence by Kim, Hyon-Jeen, PhD, Barajas, Berenice, BS, Chan, Ray Chun-Fai, PhD, Nel, Andre E., MD, PhD

“…Background Dendritic cells (DCs) play a key role as antigen-presenting cells in the immune system. There is growing evidence that the redox equilibrium of…”
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Temporal Linkage between the Phenotypic and Genomic Responses to Caloric Restriction by Dhahbi, Joseph M., Kim, Hyon-Jeen, Mote, Patricia L., Beaver, Robert J., Spindler, Stephen R., Kenyon, Cynthia J.

“…Caloric restriction (CR), the consumption of fewer calories while avoiding malnutrition, decelerates the rate of aging and the development of age-related…”
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T-cell effector pathways in allergic diseases: Transcriptional mechanisms and therapeutic targets by Chatila, Talal A., MD, Li, Ning, PhD, Garcia-Lloret, Maria, MD, Kim, Hyon-Jeen, PhD, Nel, Andre E., MD, PhD

“…Originally interpreted within the framework of a binary TH 1/TH 2 paradigm, our knowledge of the pathogenesis of atopic diseases has broadened to incorporate…”
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Age-associated increase in oxidative stress and nuclear factor kappaB activation are attenuated in rat liver by regular exercise by Radák, Zsolt, Chung, Hae Young, Naito, Hisashi, Takahashi, Ryoya, Jung, Kyung Jin, Kim, Hyon-Jeen, Goto, Sataro

“…The combined effects of aging and regular physical exercise was investigated on the production of reactive oxygen species (ROS), lipid peroxidation,…”
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The inflammation hypothesis of aging: molecular modulation by calorie restriction by Chung, H Y, Kim, H J, Kim, J W, Yu, B P

“…Current evidence strongly indicates that reactive oxygen species (ROS) and reactive nitrogen species (RNS) are widely implicated in the inflammatory process…”
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Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction by Chung, Hae Young, Kim, Hyon Jeen, Kim, Kyu Won, Choi, Jae Sue, Yu, Byung Pal

“…Accumulating evidence strongly suggests that oxidative stress underlies aging processes. Research provides consistent evidence that calorie restriction (CR)…”
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The Role of Phase II Antioxidant Enzymes in Protecting Memory T Cells from Spontaneous Apoptosis in Young and Old Mice by Kim, Hyon-Jeen, Nel, Andre E

“…Aging is associated with a functional decline and change in the phenotypic distribution of T cell subsets. The free radical theory of aging is widely promoted…”
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Gene Expression and Physiologic Responses of the Heart to the Initiation and Withdrawal of Caloric Restriction by Dhahbi, Joseph M., Tsuchiya, Tomoshi, Kim, Hyon-Jeen, Mote, Patricia L., Spindler, Stephen R.

“…Aging increases and caloric restriction (CR) decreases morbidity and mortality associated with the cardiovascular system. Using Affymetrix microarrays, we…”
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Modulation of redox-sensitive transcription factors by calorie restriction during aging by Kim, Hyon Jeen, Jung, Kyung Jin, Yu, Byung Pal, Cho, Chong Gun, Choi, Jae Sue, Chung, Hae Young

“…Oxidative stress is considered to be a major cause of aging and many age-related diseases. Calorie restriction (CR) is known to retard deleterious, age-related…”
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Dietary modulation of prostanoid synthesis in the aging process: role of cyclooxygenase-2 by Chung, Hae-Young, Kim, Hyon-Jeen, Shim, Kyung-Hee, Kim, Kyu-Won

“…To investigate the role of cyclooxygenase (COX) as a mediator for prostaglandin synthesis in relation to generation of reactive oxidant species (ROS), we…”
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Molecular exploration of age-related NF-κB/IKK downregulation by calorie restriction in rat kidney by Kim, Hyon-Jeen, Yu, Byung-Pal, Chung, Hae-Young

“…Accumulating evidence strongly suggests that oxidative stress underlies aging processes, and that in a variety of organisms, calorie restriction (CR) retards…”
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Suppression of apoptosis by calorie restriction in aged kidney by Lee, Ji Hyeon, Jung, Kyung Jin, Kim, Jung Won, Kim, Hyon Jeen, Yu, Byung Pal, Chung, Hae Young

“…Programmed cell death by apoptosis is regarded as an organism's protective mechanism against the accumulation of defective cells. Apoptotic activity is shown…”
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Influence of aging and calorie restriction on MAPKs activity in rat kidney by Kim, Hyon Jeen, Jung, Kyung Jin, Yu, Byung Pal, Cho, Chong Gun, Chung, Hae Young

“…Mitogen-activated protein kinases (MAPK), which include the extracellular signal-related kinases (ERK), the c-Jun N-terminal kinases (JNK), and the p38 MAPK,…”
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The effect of age and calorie restriction on HIF-1-responsive genes in aged liver by Kang, Min Ju, Kim, Hyon Jeen, Kim, Hyung Keun, Lee, Ji Young, Kim, Dae Hyun, Jung, Kyung Jin, Kim, Kyu Won, Baik, Hyung Suck, Yoo, Mie Ae, Yu, Byung Pal, Chung, Hae Young

“…Hypoxia inducible factor-1 (HIF-1) regulates transactivation of several genes in response to hypoxia condition. We explore hepatic HIF-1 responsive gene…”
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The Inflammation Hypothesis of Aging by Chung, Hae Young, Kim, Hyon Jeen, Kim, Jung Won, Yu, Byung Pal

“…: Current evidence strongly indicates that reactive oxygen species (ROS) and reactive nitrogen species (RNS) are widely implicated in the inflammatory process…”
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Analysis of Proteins in Aged Rat Kidney: The Effect of Calorie Restriction by Kim, Hyon-Jeen, Jeong, Hyeon-Young, Yu, Byung-Pal, Goto, Sataro, Chung, Hae-Young

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Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells by Kim, Hyon-Jeen, Barajas, Berenice, Wang, Meiying, Nel, Andre E

“…The decrease in cellular immunity with aging is of considerable public health importance. Recent studies suggest that the redox equilibrium of dendritic cells…”
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Contribution of Cyclooxygenase to Age-related Oxidative Stress by Kim, Hyon-Jeen, Yu, Byung-Pal, Yu, Mi-Ae, Kim, Kyu-Won, Woo, Jae-Suk, Chung, Hae-Young

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The effect of age on cyclooxygenase-2 gene expression by Kim, Hyon-Jeen, Kim, Kyu-Won, Yu, Byung-Pal, Chung, Hae-Young

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