Search Results - "Kim, Hong Rae"

Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics by Jarhad, Dnyandev B, Mashelkar, Karishma K, Kim, Hong-Rae, Noh, Minsoo, Jeong, Lak Shin

“…Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a member of an evolutionarily conserved family of protein kinases that belongs to the…”
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Laser‐Induced Surface Reconstruction of Nanoporous Au‐Modified TiO2 Nanowires for In Situ Performance Enhancement in Desorption and Ionization Mass Spectrometry by Kim, Moon‐Ju, Yun, Tae Gyeong, Noh, Joo‐Yoon, Song, Zhiquan, Kim, Hong‐Rae, Kang, Min‐Jung, Pyun, Jae‐Chul

“…The physicochemical properties of nanostructured substrates significantly impact laser desorption/ionization mass spectrometry (LDI‐MS) performance…”
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UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis by Heo, Mi Jeong, Kang, Sung Hyun, Kim, Yun Seok, Lee, Jung Min, Yu, Jinha, Kim, Hong‐Rae, Lim, Hyesol, Kim, Kyoung Mee, Jung, Joohee, Jeong, Lak Shin, Moon, Aree, Kim, Sang Geon

“…Activation of sterol regulatory element‐binding protein 1 (SREBP‐1), a master lipogenic transcription factor, is associated with cancer metabolism and…”
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The N-terminus of CXCR4 splice variants determines expression and functional properties by Park, Hee-Kyung, Nguyen, Lan Phuong, Nguyen, Thai Uy, Cho, Minyeong, Nguyen, Huong Thi, Hurh, Sunghoon, Kim, Hong-Rae, Seong, Jae Young, Lee, Cheol Soon, Ham, Byung-Joo, Hwang, Jong-Ik

“…C-X-C motif chemokine ligand 12(CXCL12) is an essential chemokine for organ development and homeostasis in multiple tissues. Its receptor, C-X-C chemokine…”
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Time to initiation of extracorporeal membrane oxygenation in conventional cardiopulmonary resuscitation affects the patient survival prognosis by Sim, Ji‐Hoon, Kim, Sang‐Min, Kim, Hong‐Rae, Kang, Pil‐Je, Kim, Hwa Jung, Lee, Donghee, Lee, Sang‐Wook, Choi, In‐Cheol

“…Background Cardiopulmonary resuscitation (CPR) is the cornerstone intervention for cardiac arrest, with extracorporeal CPR (ECPR) demonstrating enhanced…”
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Development of ultrafast PCR assays for the event-specific detection of eleven approved genetically modified canola events in South Korea by Park, Ji-Eun, Lee, Do-Geun, Kim, Hong-Rae, Kim, Mi-Ju, Kim, Hae-Yeong, Kim, Hyun-Joong

“…•Ultrafast PCR assays for eleven GM canola events were developed.•The specificities and the detectability of the developed assays were validated.•The developed…”
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Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues by Yoon, Ji-seong, Kim, Gyudong, Jarhad, Dnyandev B, Kim, Hong-Rae, Shin, Young-Sup, Qu, Shuhao, Sahu, Pramod K, Kim, Hea Ok, Lee, Hyuk Woo, Wang, Su Bin, Kong, Yun Jeong, Chang, Tong-Shin, Ogando, Natacha S, Kovacikova, Kristina, Snijder, Eric J, Posthuma, Clara C, van Hemert, Martijn J, Jeong, Lak Shin

“…The 6′-fluorinated aristeromycins were designed as dual-target antiviral compounds aimed at inhibiting both the viral RNA-dependent RNA polymerase (RdRp) and…”
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Design, synthesis and anticancer activity of fluorocyclopentenyl-purines and – pyrimidines by Yoon, Ji-seong, Jarhad, Dnyandev B., Kim, Gyudong, Nayak, Akshata, Zhao, Long Xuan, Yu, Jinha, Kim, Hong-Rae, Lee, Ji Yun, Mulamoottil, Varughese A., Chandra, Girish, Byun, Woong Sub, Lee, Sang Kook, Kim, Yong-Chul, Jeong, Lak Shin

“…Based on the potent anticancer activity of 6′-fluorocyclopentenyl-cytosine 2b in phase IIa clinical trials for the treatment of gemcitabine-resistant…”
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A vertically paired electrode for redox cycling and its application to immunoassays by Park, Jun-Hee, Lee, Ga-Yeon, Song, Zhiquan, Bong, Ji-Hong, Kim, Hong-Rae, Kang, Min-Jung, Pyun, Jae-Chul

“…An electrochemical immunoassay based on the redox cycling method was presented using vertically paired electrodes (VPEs), which were fabricated using…”
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One-step immunoassay without washing steps for influenza A virus detection using ISFET by Bong, Ji-Hong, Kim, Hong-Rae, Yoo, Jae-Woo, Kang, Min-Jung, Shin, Myung-Geun, Lee, Jung-Su, Shim, Won-Bo, Lee, Sang-Dae, Pyun, Jae-Chul

“…A one-step immunoassay for influenza A virus detection was developed using two different microbeads and a filter-inserted bottle. Two bead types with diameters…”
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Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor by Nguyen, Lan Phuong, Cho, Minyeong, Nguyen, Thai Uy, Park, Hee-Kyung, Nguyen, Huong Thi, Mykhailova, Kateryna, Hurh, Sunghoon, Kim, Hong-Rae, Seong, Jae Young, Lee, Cheol Soon, Ham, Byung-Joo, Hwang, Jong-Ik

“…Tachykinins and their cognate receptors, neurokinin receptors (NKs) including NK1, NK2, and NK3 play vital roles in regulating various physiological processes…”
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Discovery of Chemical Scaffolds as Lysophosphatidic Acid Receptor 1 Antagonists: Virtual Screening, In Vitro Validation, and Molecular Dynamics Analysis by Nguyen, Lan Phuong, Khan, Rasel Ahmed, Kang, Soomin, Lee, Hobin, Hwang, Jong-Ik, Kim, Hong-Rae

“…Lysophosphatidic acid receptor 1 (LPAR1) is an emerging therapeutic target for numerous human diseases including fibrosis. However, the limited number of…”
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Modified Bicaval Technique in Orthotopic Heart Transplantation　― Comparison With Conventional Bicaval Technique by Kim, Hong Rae, Jung, Sung-Ho, Kim, Jae-Joong, Yang, Dong Hyun, Yun, Tae-Jin, Lee, Jae Won

“…Background: Orthotopic heart transplantation (HT) is the treatment of choice for patients with end-stage heart failure (HF). The bicaval technique was…”
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Surgical Outcomes of Centrifugal Continuous-Flow Implantable Left Ventricular Assist Devices: Heartmate 3 versus Heartware Ventricular Assist Device by Shin, Kinam, Cho, Won Chul, Shin, Nara, Kim, Hong Rae, Kim, Min-Seok, Chung, Cheol Hyun, Jung, Sung-Ho

“…Background: Left ventricular assist devices (LVADs) are widely employed as a therapeutic option for end-stage heart failure. We evaluated the outcomes…”
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Stereoselective Synthesis of Anti‐Hepatitis B Drug, Entecavir, through Regio‐ and Stereoselective Epoxide Cleavage by Hyun, Young Eum, Kim, Hong‐Rae, Choi, Yongseok, Jeong, Lak Shin

“…A stereoselective synthesis of entecavir, an anti‐hepatitis B (HBV) drug, was accomplished by a regioselective isopropylidene cleavage, stereoselective…”
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One-step immunoassay based on switching peptides for analyzing ochratoxin A in wines by Kim, Tae-Hun, Bong, Ji-Hong, Kim, Hong-Rae, Shim, Won-Bo, Kang, Min-Jung, Pyun, Jae-Chul

“…A one-step immunoassay is presented for the detection of ochratoxin A (OTA) using an antibody complex with switching peptides. Because the switching peptides…”
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Asymmetric Synthesis of Fluoro‐MLN4924 as a Selective NEDD8‐Activating Enzyme (NAE) Inhibitor by Kim, Hong‐Rae, Jarhad, Dnyandev B., Sahu, Pramod K., Sung, Kisu, An, Dayoung, Hyun, Young Eum, Yu, Jinha, Jeong, Lak Shin

“…Based on bioisosteric rationale, fluorinated analogues of MLN4924, which is a selective NEDD8‐activating enzyme inhibitor, were designed and their asymmetric…”
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Covalent Small Molecule Immunomodulators Targeting the Protease Active Site by Kim, Hong-Rae, Tagirasa, Ravichandra, Yoo, Euna

“…Cells of the immune system utilize multiple proteases to regulate cell functions and orchestrate innate and adaptive immune responses. Dysregulated protease…”
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Development of a Real-Time PCR Assay for the Detection of Donkey (Equus asinus) Meat in Meat Mixtures Treated under Different Processing Conditions by Kim, Mi-Ju, Suh, Seung-Man, Kim, Sung-Yeon, Qin, Pei, Kim, Hong-Rae, Kim, Hae-Yeong

“…In this study, a donkey-specific primer pair and probe were designed from mitochondrial cytochrome b gene for the detection of raw donkey meat and different…”
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Single-Stage Open Repair of Extensive Arch and Descending Thoracic Aneurysm through Sternotomy: A Case Report by Kim, Joon Young, Kim, Hong Rae, Kim, Joon Bum

“…Extensive thoracic aortic disease involving the ascending aorta, the aortic arch, and the descending thoracic aorta may require multiple surgical and…”
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