Search Results - "Kim, Ha‐Gyeong"

BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production by Kim, Yunha, Kim, Yong-Sook, Kim, Dong Eun, Lee, Jee Suk, Song, Ji Hoon, Kim, Ha-Gyeong, Cho, Dong-Hyung, Jeong, Seong-Yun, Jin, Dong-Hoon, Jang, Se Jin, Seol, Hyang-Sook, Suh, Young-Ah, Lee, Seung Jin, Kim, Choung-Soo, Koh, Jae-Young, Hwang, Jung Jin

“…We screened a chemical library in MCF-7 cells stably expressing green fluorescent protein (GFP)-conjugated microtubule-associated protein 1 light chain 3 (LC3)…”
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Combination treatment with docetaxel and histone deacetylase inhibitors downregulates androgen receptor signaling in castration-resistant prostate cancer by Park, Sang Eun, Kim, Ha-Gyeong, Kim, Dong Eun, Jung, Yoo Jung, Kim, Yunlim, Jeong, Seong-Yun, Choi, Eun Kyung, Hwang, Jung Jin, Kim, Choung-Soo

“…Summary Backgrounds Since most patients with castration-resistant prostate cancer (CRPC) develop resistance to its standard therapy docetaxel, many studies…”
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Downregulation of androgen receptors by NaAsO2 via inhibition of AKT‐NF‐κB and HSP90 in castration resistant prostate cancer by Kim, Yunlim, Park, Sang Eun, Moon, Jeong‐Weon, Kim, Bong‐Min, Kim, Ha‐Gyeong, Jeong, In Gab, Yoo, Sangjun, Ahn, Jae Beom, You, Dalsan, Pak, Jhang Ho, Kim, Sujong, Hwang, Jung Jin, Kim, Choung‐Soo

“…Background Androgen and androgen receptor (AR) play essential roles in the development and maintenance of prostate cancer. The recently identified AR splice…”
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NQO1 regulates cell cycle progression at the G2/M phase by Oh, Eun-Taex, Kim, Ha Gyeong, Kim, Chul Hoon, Lee, Jeonghun, Kim, Chulhee, Lee, Jae-Seon, Cho, Yunmi, Park, Heon Joo

“…Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) is associated with tumor cell proliferation and growth in several human cancer types. However, the…”
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Mesoporous Silica Nanocarriers with Cyclic Peptide Gatekeeper: Specific Targeting of Aminopeptidase N and Triggered Drug Release by Stimuli‐Responsive Conformational Transformation by Lee, Jeonghun, Oh, Eun‐Taex, Han, Yeji, Kim, Ha Gyeong, Park, Heon Joo, Kim, Chulhee

“…Utilizing stimuli‐responsive conformational transformation of a cyclic peptide as a gatekeeper for mesoporous nanocarriers has several advantages such as…”
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Quinacrine-Mediated Inhibition of Nrf2 Reverses Hypoxia-Induced 5-Fluorouracil Resistance in Colorectal Cancer by Kim, Ha Gyeong, Kim, Chan Woo, Lee, Don Haeng, Lee, Jae-Seon, Oh, Eun-Taex, Park, Heon Joo

“…5-Fluorouracil (5-FU) is an important chemotherapeutic agent for the systemic treatment of colorectal cancer (CRC), but its effectiveness against CRC is…”
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Stimulus‐Induced Conformational Transformation of a Cyclic Peptide for Selective Cell‐Targeting On–Off Gatekeeper for Mesoporous Nanocarriers by Lee, Jeonghun, Oh, Eun‐Taex, Song, Jaehun, Kim, Ha Gyeong, Park, Heon Joo, Kim, Chulhee

“…αvβ3 Integrin is upregulated on many cancer cells. We designed a dual functional cyclic peptide gatekeeper with a capability of stimuli‐responsive…”
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Multi-Layer Nanofibrous PCL Scaffold-Based Colon Cancer Cell Cultures to Mimic Hypoxic Tumor Microenvironment for Bioassay by Oh, Eun-Taex, Kim, Ha Gyeong, Choi, Min-Ho, Lee, Jae-Seon, Kim, Sang Jeong, Kwak, Jong-Young, Park, Heon Joo

“…Three-dimensional (3D) cancer cell culture systems have been developed to aid the study of molecular mechanisms in cancer development, identify therapeutic…”
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Quasi-Irreversible Inhibition of CYP2D6 by Berberine by Kim, Ha Gyeong, Lee, Han Sol, Jeon, Jang Su, Choi, Young Jae, Choi, Yeon Jung, Yoo, So-Yeol, Kim, Eun-yeong, Lee, Kiho, Park, InWha, Park, Han-Jin, Cho, Seung-Woo, Kim, Jong-Hoon, Lee, Jae-Young, Kim, Sang Kyum

“…In our previous study, Hwang-Ryun-Hae-Dok-Tang, which contains berberine (BBR) as a main active ingredient, inhibited cytochrome P450 (CYP) 2D6 in a…”
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Downregulation of androgen receptors by NaAsO 2 via inhibition of AKT-NF-κB and HSP90 in castration resistant prostate cancer by Kim, Yunlim, Park, Sang Eun, Moon, Jeong-Weon, Kim, Bong-Min, Kim, Ha-Gyeong, Jeong, In Gab, Yoo, Sangjun, Ahn, Jae Beom, You, Dalsan, Pak, Jhang Ho, Kim, Sujong, Hwang, Jung Jin, Kim, Choung-Soo

“…Androgen and androgen receptor (AR) play essential roles in the development and maintenance of prostate cancer. The recently identified AR splice variants…”
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Effects of rifampicin on hepatic antioxidant enzymes in PXR and CAR double humanized mice by Choi, Young Jae, Ryu, Chang Seon, Lee, Sang Yoon, Kim, Ha Gyeong, Kim, Nan Young, Lee, Ji-Yoon, Oh, Soo Jin, Park, Han-Jin, Cho, Seung-Woo, Kim, Jong-Hoon, Kim, Sang Kyum

“…Background Nuclear receptor are major regulators of hepatic drug metabolizing enzymes and antioxidants enzymes. Nuclear receptor humanized mice were used for…”
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NQO1 regulates cell cycle progression at the G2/M phase by Oh, Eun-Taex, Kim, Ha Gyeong, Kim, Chul Hoon, Lee, Jeonghun, Kim, Chulhee, Lee, Jae-Seon, Cho, Yunmi, Park, Heon Joo

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Identification of miR-6794-3p as a suppressor in pancreatic cancer metastasis by Kim, Ha Gyeong, Cho, Yunmi, Lee, Jae-Seon, Oh, Eun-Taex, Park, Heon Joo

“…Metastasis is a major cause of treatment failure in patients with pancreatic cancer, highlighting the urgent need for effective therapeutic strategies. Here,…”
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Stimuli-Responsive Conformational Transformation of Peptides for Tunable Cytotoxicity by Lee, Jeonghun, Oh, Eun-Taex, Lee, Hanwool, Kim, Jiwon, Kim, Ha Gyeong, Park, Heon Joo, Kim, Chulhee

“…The stimuli-responsive conformational transformation of peptides possessing a constrained form triggered by specific biological microenvironment would provide…”
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Mesoporous Silica Nanocarriers with Cyclic Peptide Gatekeeper: Specific Targeting of AminopeptidaseN and Triggered Drug Release by Stimuli-Responsive Conformational Transformation by Lee, Jeonghun, Oh, Eun-Taex, Han, Yeji, Kim, Ha Gyeong, Park, Heon Joo, Kim, Chulhee

“…Utilizing stimuli-responsive conformational transformation of a cyclic peptide as a gatekeeper for mesoporous nanocarriers has several advantages such as…”
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Brusatol-Mediated Inhibition of c-Myc Increases HIF-1α Degradation and Causes Cell Death in Colorectal Cancer under Hypoxia by Oh, Eun-Taex, Kim, Chan Woo, Kim, Ha Gyeong, Lee, Jae-Seon, Park, Heon Joo

“…HIF-1 (hypoxia-inducible factor-1) regulates the expression of ~100 genes involved in angiogenesis, metastasis, tumor growth, chemoresistance and…”
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Abstract 455: Identification of hsa-miR-6794-3p as a key regulatory factor in human pancreatic cancer metastasis by Kim, Ha Gyeong, Oh, Eun-Taex, Cho, Yunmi, Park, Heon Joo

“…Metastasis is a major factor in treatment failure in patients with pancreatic cancer, but the underlying mechanisms remain unclear, and new, effective…”
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Abstract 6959: Acetylcholine potentiates invasion and migration of human pancreatic cancer cells under hypoxia through α7 nAChR-mediated increases in HIF-1α expression by Cho, Yunmi, Oh, Eun-Taex, Kim, Ha Gyeong, Park, Heon Joo

“…The most significant nerve-related problem in clinical pancreatic cancer management is perineural invasion (PNI), characterized as the neoplastic invasion of…”
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Abstract B110: Brusatol-induced degradation of HIF-1α by inhibiting c-Myc causes colorectal cancer cell death under hypoxia by Oh, Eun-Taex, Kim, Chan Woo, Kim, Ha Gyeong, Park, Heon Joo

“…Hypoxia-inducible factor-1 (HIF-1) regulates the expression of ~100 genes involved in metastasis, tumor growth, angiogenesis, chemoresistance, and…”
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Abstract 2675: Quinacrine-mediated activation of JNK1 inhibits Nrf2 and causes cell death in human colon cancer by Oh, Eun-Taex, Kim, Chan-Woo, Kim, Ha Gyeong, Lee, In-Seon, Lee, Chae Won, Park, Heon Joo

“…Up-regulation of Nrf2 is associated with poor prognosis in skin, breast, prostate, lung, head and neck, endometrial, and colorectal cancer, and increases…”
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