Search Results - "Kim, H.T."

Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 mutation by Park, S.J, Kim, H.T, Lee, D.H, Kim, K.P, Kim, S.-W, Suh, C, Lee, J.S

“…Abstract Non-small cell lung cancer (NSCLC) harboring an activating epidermal growth factor receptor (EGFR) mutation shows good and rapid response to EGFR…”
Get full text

Fibroblast-mediated drug resistance in cancer by Paraiso, Kim H.T., Smalley, Keiran S.M.

“…Tumor progression relies upon the dynamic interaction of cancer cells with host fibroblasts, endothelial cells, immune cells and components of the…”
Get full text

Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma by Fedorenko, Inna V., Paraiso, Kim H.T., Smalley, Keiran S.M.

“…The discovery of activating BRAF V600E mutations in 50% of all cutaneous melanomas has revolutionized the understanding of melanoma biology and provided new…”
Get full text

PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression by PARAISO, Kim H. T, YUN XIANG, RIBAS, Antoni, DALLA PALMA, Maurizia, NATHANSON, Katherine L, KOOMEN, John M, MESSINA, Jane L, SMALLEY, Keiran S. M, REBECCA, Vito W, ABEL, Ethan V, CHEN, Y. Ann, MUNKO, A. Cecilia, WOOD, Elizabeth, FEDORENKO, Inna V, SONDAK, Vernon K, ANDERSON, Alexander R. A

“…This study addresses the role of PTEN loss in intrinsic resistance to the BRAF inhibitor PLX4720. Immunohistochemical staining of a tissue array covering all…”
Get full text

Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes by Wu, Hao, Rahman, H N Ashiqur, Dong, Yunzhou, Liu, Xiaolei, Lee, Yang, Wen, Aiyun, To, Kim Ht, Xiao, Li, Birsner, Amy E, Bazinet, Lauren, Wong, Scott, Song, Kai, Brophy, Megan L, Mahamud, M Riaj, Chang, Baojun, Cai, Xiaofeng, Pasula, Satish, Kwak, Sukyoung, Yang, Wenxia, Bischoff, Joyce, Xu, Jian, Bielenberg, Diane R, Dixon, J Brandon, D'Amato, Robert J, Srinivasan, R Sathish, Chen, Hong

“…Impaired lymphangiogenesis is a complication of chronic complex diseases, including diabetes. VEGF-C/VEGFR3 signaling promotes lymphangiogenesis, but how this…”
Get full text

Toroidal injection angle dependence of EC assisted plasma initiation at DIII-D by Yang, J., Sips, A.C.C., de Vries, P., Sinha, J., Kim, H.T., Glass, F., Austin, M., van Zeeland, M., Herfindal, J.L., Shafer, M., Nelson, A.O., Marini, C., Yoo, M.G.

“…Abstract An experimental scan of the electron cyclotron waves (EC) toroidal injection angle in plasma breakdown is performed at the DIII-D tokamak. The second…”
Get full text

The HSP90 Inhibitor XL888 Overcomes BRAF Inhibitor Resistance Mediated through Diverse Mechanisms by PARAISO, Kim H. T, HAARBERG, H. Eirik, JOHN, Jobin K, SARNAIK, Amod A, KOOMEN, John M, SMALLEY, Keiran S. M, WOOD, Elizabeth, REBECCA, Vito W, CHEN, Y. Ann, YUN XIANG, RIBAS, Antoni, LO, Roger S, WEBER, Jeffrey S, SONDAK, Vernon K

“…The clinical use of BRAF inhibitors is being hampered by the acquisition of drug resistance. This study shows the potential therapeutic use of the HSP90…”
Get full text

Inhibition of HSP90 by AT13387 delays the emergence of resistance to BRAF inhibitors and overcomes resistance to dual BRAF and MEK inhibition in melanoma models by Smyth, Tomoko, Paraiso, Kim H T, Hearn, Keisha, Rodriguez-Lopez, Ana M, Munck, Joanne M, Haarberg, H Eirik, Sondak, Vernon K, Thompson, Neil T, Azab, Mohammad, Lyons, John F, Smalley, Keiran S M, Wallis, Nicola G

“…Emergence of clinical resistance to BRAF inhibitors, alone or in combination with MEK inhibitors, limits clinical responses in melanoma. Inhibiting HSP90…”
Get full text

Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype by Paraiso, Kim H T, Das Thakur, Meghna, Fang, Bin, Koomen, John M, Fedorenko, Inna V, John, Jobin K, Tsao, Hensin, Flaherty, Keith T, Sondak, Vernon K, Messina, Jane L, Pasquale, Elena B, Villagra, Alejandro, Rao, Uma N, Kirkwood, John M, Meier, Friedegund, Sloot, Sarah, Gibney, Geoffrey T, Stuart, Darrin, Tawbi, Hussein, Smalley, Keiran S M

“…Many patients with BRAF inhibitor resistance can develop disease at new sites, suggesting that drug-induced selection pressure drives metastasis. Here, we used…”
Get more information

Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy by Cooke, M.E, Allon, A.A, Cheng, T, Kuo, A.C, Kim, H.T, Vail, T.P, Marcucio, R.S, Schneider, R.A, Lotz, J.C, Alliston, T

“…Summary Objective This study investigated a novel approach to induce chondrogenic differentiation of human mesenchymal stem cells (hMSC). We hypothesized that…”
Get full text

Vulvar Recurrences Following Intensity Modulated Radiation Therapy for Squamous Cell Carcinoma of the Anus by Bagshaw, H.P, Sause, W.T, Gawlick, U, Kim, H.T, Whisenaut, J.R, Cannon, G.M

Get full text

Dynamics of Population Code for Working Memory in the Prefrontal Cortex by Baeg, E.H., Kim, Y.B., Huh, K., Mook-Jung, I., Kim, H.T., Jung, M.W.

“…Some neurons (delay cells) in the prefrontal cortex elevate their activities throughout the time period during which the animal is required to remember past…”
Get full text

Long-term Clinical Outcomes of Kidney Re-transplantation by Yeo, S.M, Kim, Y, Kang, S.S, Park, W.Y, Jin, K, Park, S.B, Park, U.J, Kim, H.T, Cho, W.H, Han, S

“…Abstract Background Kidney re-transplantation is commonly considered to have a higher immunological risk than first kidney transplantation. Because of the…”
Get full text

Successful Treatment of Disseminated Adenovirus Infection With Ribavirin and Intravenous Immunoglobulin in an Adult Renal Transplant Recipient: A Case Report by Park, U.J, Hyun, S.K, Kim, H.T, Cho, W.H, Han, S.Y

“…Abstract Disseminated adenovirus infection in recipients of renal transplants is a rare but often fatal complication. We present a case of a 32-year-old woman…”
Get full text

Immune Reconstitution of B Cells Following Allogeneic Hematopoietic Cell Transplantation by ABOALELA, A, KIM, H.T, ALHO, A, REYNOLDS, C, CHAMMAS, M.J, RITZO, J

Get full text

Long-term Clinical Outcomes of First and Second Kidney Transplantation in Patients With Biopsy-Proven IgA Nephropathy by Kim, Y, Yeo, S.M, Kang, S.S, Park, W.Y, Jin, K, Park, S.B, Park, U.J, Kim, H.T, Han, S

“…Abstract Introduction The recurrence of IgA nephropathy (IgAN) after kidney transplantation (KT) has an effect on graft survival, but there are few reports…”
Get full text

Efficacy of everolimus in tuberous sclerosis with renal angiomyolipoma by Choi, S.H., Chung, J.W., Ha, Y.S., Lee, J.N., Kim, B.S., Kim, H.T., Kim, T.H., Yoo, E.S., Kwon, T.G.

Get full text

True 7nm Platform Technology featuring Smallest FinFET and Smallest SRAM cell by EUV, Special Constructs and 3rd Generation Single Diffusion Break by Jeong, W.C., Kwon, D.J., Nam, K.J., Rim, W.J., Jang, M.S., Kim, H.T., Lee, Y.W., Park, J.S., Lee, E.C., Ha, D.W., Park, C.H., Maeda, S., Cho, H.-J., Jung, S.-M., Kang, H.K., Lee, H.J., Lee, K.W., Lee, T.J., Park, D.W., Kim, B.S., Do, J.H., Fukai, T.

“…7nm platform technology that takes full advantage of EUV lithography was developed, where EUV was straightforwardly used for single patterning of MOL and BEOL,…”
Get full text

Outcomes of topical steroid therapy depending on steroid potency for boys with symptomatic phimosis by Ha, Y., Park, K.M., Park, D.J., Chung, J., Choi, S.H., Lee, J.N., Kim, B.S., Kim, H.T., Kim, T., Yoo, E.S., Kwon, T.G.

Get full text

Comparison of recurrence rate of urolithiasis according to the stone composition in patients without dietary modification by Ha, Y., Park, K.M., Park, D.J., Chung, J., Choi, S.H., Lee, J.N., Kim, B.S., Kim, H.T., Kim, T., Yoo, E.S., Kwon, T.G.

Get full text