Search Results - "Kim, Gyu Lee"

The ClpXP Protease Contributes to Staphylococcus aureus Pneumonia by Kim, Gyu-Lee, Akoolo, Lavoisier, Parker, Dane

“…Abstract Staphylococcus aureus is a leading cause of pneumonia. We show here that the ClpXP protease involved in protein turnover is important for pathogenesis…”
Get full text

Impact of the pentose phosphate pathway on metabolism and pathogenesis of Staphylococcus aureus by Kim, Jisun, Kim, Gyu-Lee, Norambuena, Javiera, Boyd, Jeffrey M, Parker, Dane

“…Staphylococcus aureus is an important pathogen that leads to significant disease through multiple routes of infection. We recently published a transposon…”
Get full text

Pneumonia and Streptococcus pneumoniae vaccine by Kim, Gyu-Lee, Seon, Seung-Han, Rhee, Dong-Kwon

“…Pneumonia is an inflammatory disease of the lung, responsible for high morbidity and mortality worldwide. It is caused by bacteria, viruses, fungi, or other…”
Get full text

Immunogenicity and Protective Efficacy of Recombinant Protective Antigen Anthrax Vaccine (GC1109) in A/J Mice Model by Kim, Gyu-Lee, Pyo, Seong Wook, Yi, Hwajung, Kim, So-Hyeon, Shin, Hwachul, Yu, Min-Ah, Hwang, Yi-Rang, Choi, Sang-Yoon, Jeon, Jun Ho, Jo, Su Kyoung, Rhie, Gi-eun

“…•The immunogenicity and efficacy of GC1109 were tested using A/J mice model.•A booster dose of GC1109 after 3 serial vaccinations enhanced the level of anti-PA…”
Get full text

Growth and Stress Tolerance Comprise Independent Metabolic Strategies Critical for Staphylococcus aureus Infection by Kim, Gyu-Lee, Hooven, Thomas A, Norambuena, Javiera, Li, Barry, Boyd, Jeffrey M, Yang, Jason H, Parker, Dane

“…Staphylococcus aureus is an important pathogen that leads to high morbidity and mortality. Although S. aureus produces many factors important for pathogenesis,…”
Get full text

Estrogen receptor‐β of microglia underlies sexual differentiation of neuronal protection via ginsenosides in mice brain by Lee, Seungyeop, Lee, Si‐On, Kim, Gyu‐Lee, Rhee, Dong‐Kwon

“…Summary Aims Streptococcus pneumoniae infection in acute bacterial meningitis can lead to widespread brain damage and mortality. Inflammatory responses by…”
Get full text

Staphylococcal DNA Repair Is Required for Infection by Ha, Kam Pou, Clarke, Rebecca S, Kim, Gyu-Lee, Brittan, Jane L, Rowley, Jessica E, Mavridou, Despoina A I, Parker, Dane, Clarke, Thomas B, Nobbs, Angela H, Edwards, Andrew M

“…To cause infection, must withstand damage caused by host immune defenses. However, the mechanisms by which staphylococcal DNA is damaged and repaired during…”
Get full text

Pep27 Mutant Immunization Inhibits Caspase-14 Expression to Alleviate Inflammatory Bowel Disease via Treg Upregulation by Iqbal, Hamid, Kim, Gyu-Lee, Kim, Ji-Hoon, Ghosh, Prachetash, Shah, Masaud, Lee, Wonsik, Rhee, Dong-Kwon

“…Inflammatory bowel disease (IBD) is a highly prevalent gut inflammatory disorder. Complicated clinical outcomes prolong the use of conventional therapy and…”
Get full text

Effect of decreased BCAA synthesis through disruption of ilvC gene on the virulence of Streptococcus pneumoniae by Kim, Gyu-Lee, Lee, Seungyeop, Luong, Truc Thanh, Nguyen, Cuong Thach, Park, Sang-Sang, Pyo, Suhkneung, Rhee, Dong-Kwon

“…Streptococcus pneumoniae (pneumococcus) is responsible for significant morbidity and mortality worldwide. It causes a variety of life-threatening infections…”
Get full text

Korean Red Ginseng inhibits apoptosis in neuroblastoma cells via estrogen receptor β-mediated phosphatidylinositol-3 kinase/Akt signaling by Nguyen, Cuong Thach, Luong, Truc Thanh, Kim, Gyu-Lee, Pyo, Suhkneung, Rhee, Dong-Kwon

“…Ginseng has been shown to exert antistress effects both in vitro and in vivo. However, the effects of ginseng on stress in brain cells are not well understood…”
Get full text

ATF3 provides protection from Staphylococcus aureus and Listeria monocytogenes infections by Nguyen, Cuong T., Luong, Truc T., Lee, Sung-Yoep, Kim, Gyu-Lee, Pyo, Suhkneung, Rhee, Dong-Kwon

“…Activating transcription factor 3 (ATF3) is a stress-induced transcriptional regulator in eukaryote. The role of ATF3 in cancer has been well defined, but how…”
Get full text

Effect of Korean Red Ginseng extracts on drug-drug interactions by Kim, Se-Jin, Choi, Seungmok, Kim, Minsoo, Park, Changmin, Kim, Gyu-Lee, Lee, Si-On, Kang, Wonku, Rhee, Dong-Kwon

“…Ginseng has been the subject of many experimental and clinical studies to uncover the diverse biological activities of its constituent compounds. It is a…”
Get full text

Induction of the pneumococcal vncRS operon by lactoferrin is essential for pneumonia by Lee, Seungyeop, Ghosh, Prachetash, Kwon, Hyogyoung, Park, Sang-Sang, Kim, Gyu-Lee, Choi, Sang-Yoon, Kim, Eun-Hye, Tran, Thao Dang-Hien, Seon, Seung Han, Le, Nhat Tu, Iqbal, Hamid, Lee, Sangho, Pyo, Suhkneung, Rhee, Dong-Kwon

“…Streptococcus pneumoniae (pneumococcus), the major pathogen for pneumonia, commonly colonizes the lung, but the mechanism underlying the coordination of…”
Get full text

Pneumococcal pep27-mutant inhibits Wnt5a expression via the regulation of T helper cells to attenuate colitis by Iqbal, Hamid, Kim, Gyu-Lee, Kim, Ji-Hoon, Ghosh, Prachetash, Shah, Masaud, Lee, Wonsik, Rhee, Dong-Kwon

“…•During lung infection, pneumococcal pep27 is induced and elicits oxidative damage.•pep27 mutant (Δpep27) was devoid of blood invasion ability and became…”
Get full text

Effect of Korean Red Ginseng extracts on drug-drug interactions by Kim, Se-Jin, Choi, Seungmok, Kim, Minsoo, Park, Changmin, Kim, Gyu-Lee, Lee, Si-On, Kang, Wonku, Rhee, Dong-Kwon

“…Background: Ginseng has been the subject of many experimental and clinical studies to uncover the diverse biological activities of its constituent compounds…”
Get full text

Pulmonary Colonization Resistance to Pathogens via Noncanonical Wnt and Interleukin-17A by Intranasal pep27 Mutant Immunization by Kim, Gyu-Lee, Lee, Seungyeop, Kim, Se-Jin, Lee, Si-On, Pyo, Suhkneung, Rhee, Dong-Kwon

“…Previous studies have focused on colonization resistance of the gut microbiota against antibiotic resistant strains. However, less research has been performed…”
Get full text

Inhibition of Autolysis by Lipase LipA in Streptococcus pneumoniae Sepsis by Kim, Gyu-Lee, Luong, Truc Thanh, Park, Sang-Sang, Lee, Seungyeop, Ha, Jung Ah, Nguyen, Cuong Thach, Ahn, Ji Hye, Park, Ki-Tae, Paik, Man-Jeong, Pyo, Suhkneung, Briles, David E, Rhee, Dong-Kwon

“…More than 50% of sepsis cases are associated with pneumonia. Sepsis is caused by infiltration of bacteria into the blood via inflammation, which is triggered…”
Get full text

A comparative study of changes in smoking cessation attempt rates and related factors before and during COVID-19 by Lee, Hyo Young, Lee, Seung Hun, Kim, Gyu Lee

“…This study aimed to identify whether smoking cessation attempts (SCA) for health promotion changed during the coronavirus disease 2019 (COVID-19) pandemic and…”
Get full text

Korean Red Ginseng inhibits apoptosis in neuroblastoma cells via estrogen receptor ${\beta}$-mediated phosphatidylinositol-3 kinase/Akt signaling by Nguyen, Cuong Thach, Luong, Truc Thanh, Kim, Gyu-Lee, Pyo, Suhkneung, Rhee, Dong-Kwon

“…Background: Ginseng has been shown to exert antistress effects both in vitro and in vivo. However, the effects of ginseng on stress in brain cells are not well…”
Get full text

ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1β Activation During Streptococcus pneumoniae Infection by Lee, Seungyeop, Kim, Gyu-Lee, Kim, Na Young, Kim, Se-Jin, Ghosh, Prachetash, Rhee, Dong-Kwon

“…Activating transcription factor-3 (ATF3) in the ER stress pathway induces cytokine production and promotes survival during gram-positive bacterial infection…”
Get full text