Search Results - "Kim, Gye Lim"
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Dual Effect of Chemo-PDT with Tumor Targeting Nanoparticles Containing iRGD Peptide
Published in Pharmaceutics (01-02-2023)“…Nanotechnology, including self-aggregated nanoparticles, has shown high effectiveness in the treatment of solid tumors. To overcome the limitations of…”
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Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy
Published in Biomaterials research (26-05-2023)“…Claudin-4 (CLDN4), a tight junction protein, is overexpressed in several types of cancer, and is considered a biomarker for cancer-targeted treatment. CLDN4 is…”
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Hypoxia-responsive folic acid conjugated glycol chitosan nanoparticle for enhanced tumor targeting treatment
Published in International journal of pharmaceutics (30-04-2020)“…[Display omitted] Hypoxia is a characteristic feature of various ischemic diseases, including cancer. This study describes the development of glycol chitosan…”
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Amentoflavone, active compound of Selaginella tamariscina, inhibits in vitro and in vivo TGF-β-induced metastasis of human cancer cells
Published in Archives of biochemistry and biophysics (15-07-2020)“…Epithelial mesenchymal transition (EMT) is a well-known and important step in metastasis and thus can be a key target in cancer treatment. Here, we tested the…”
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Bakuchiol, main component of root bark of Ulmus davidiana var. japonica, inhibits TGF-β-induced in vitro EMT and in vivo metastasis
Published in Archives of biochemistry and biophysics (30-09-2021)“…Cancer is a second leading cause of death worldwide, and metastasis is the major cause of cancer-related mortality. The epithelial–mesenchymal transition…”
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Hypoxia-responsive, organic-inorganic hybrid mesoporous silica nanoparticles for triggered drug release
Published in Journal of drug delivery science and technology (01-04-2020)“…Hypoxia is a manifestation of various diseases with an ischemic component, including cancer. Tumor hypoxia is a hallmark of cancer, creating an opportunity to…”
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