Search Results - "Kim, Gi Bae"

Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase by Ahn, Jung Ho, Seo, Hogyun, Park, Woojin, Seok, Jihye, Lee, Jong An, Kim, Won Jun, Kim, Gi Bae, Kim, Kyung-Jin, Lee, Sang Yup

“…Succinic acid (SA), a dicarboxylic acid of industrial importance, can be efficiently produced by metabolically engineered Mannheimia succiniciproducens …”
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Current status and applications of genome-scale metabolic models by Gu, Changdai, Kim, Gi Bae, Kim, Won Jun, Kim, Hyun Uk, Lee, Sang Yup

“…Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction associations for entire metabolic genes in an organism, and can be…”
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Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production by Ko, Yoo-Sung, Kim, Je Woong, Lee, Jong An, Han, Taehee, Kim, Gi Bae, Park, Jeong Eum, Lee, Sang Yup

“…Sustainable production of chemicals from renewable non-food biomass has become a promising alternative to overcome environmental issues caused by our heavy…”
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An interactive metabolic map of bio-based chemicals by Jang, Woo Dae, Kim, Gi Bae, Lee, Sang Yup

“…Metabolic engineering for the bio-based production of chemicals requires thorough understanding of metabolic reactions including enzymes, cofactors, reactants,…”
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Metabolic engineering for sustainability and health by Kim, Gi Bae, Choi, So Young, Cho, In Jin, Ahn, Da-Hee, Lee, Sang Yup

“…During the past three decades, metabolic engineering (ME) has made great contributions to solving global challenges such as climate crisis, depletion of fossil…”
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Metabolic engineering of Mannheimia succiniciproducens for malic acid production using dimethylsulfoxide as an electron acceptor by Lee, Jong An, Ahn, Jung Ho, Kim, Gi Bae, Choi, Sol, Kim, Ji Yeon, Lee, Sang Yup

“…Microbial production of various TCA intermediates and related chemicals through the reductive TCA cycle has been of great interest. However, rumen bacteria…”
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Functional annotation of enzyme-encoding genes using deep learning with transformer layers by Kim, Gi Bae, Kim, Ji Yeon, Lee, Jong An, Norsigian, Charles J., Palsson, Bernhard O., Lee, Sang Yup

“…Functional annotation of open reading frames in microbial genomes remains substantially incomplete. Enzymes constitute the most prevalent functional gene class…”
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Synthetic Formatotrophs for One‐Carbon Biorefinery by Bang, Junho, Ahn, Jung Ho, Lee, Jong An, Hwang, Chang Hun, Kim, Gi Bae, Lee, Jinwon, Lee, Sang Yup

“…The use of CO2 as a carbon source in biorefinery is of great interest, but the low solubility of CO2 in water and the lack of efficient CO2 assimilation…”
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Glutaric acid production by systems metabolic engineering of an L-lysine–overproducing Corynebacterium glutamicum by Han, Taehee, Kim, Gi Bae, Lee, Sang Yup

“…There is increasing industrial demand for five-carbon platform chemicals, particularly glutaric acid, a widely used building block chemical for the synthesis…”
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Understanding the metabolism of infants using whole-body metabolic models by Lee, Sang Yup, Kim, Gi Bae

“…A whole-body model is a computational representation of sex-specific and organ-resolved whole-body metabolism. In this issue of Cell Metabolism, Zaunseder…”
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Machine learning applications in systems metabolic engineering by Kim, Gi Bae, Kim, Won Jun, Kim, Hyun Uk, Lee, Sang Yup

“…[Display omitted] •Application of machine learning in biotechnology is becoming essential.•Machine learning is increasingly applied to advance systems…”
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DeepTFactor: A deep learning-based tool for the prediction of transcription factors by Kim, Gi Bae, Gao, Ye, Palsson, Bernhard O., Lee, Sang Yup

“…A transcription factor (TF) is a sequence-specific DNA-binding protein that modulates the transcription of a set of particular genes, and thus regulates gene…”
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Applications of artificial intelligence to enzyme and pathway design for metabolic engineering by Jang, Woo Dae, Kim, Gi Bae, Kim, Yeji, Lee, Sang Yup

“…[Display omitted] •The recent applications of AI in enzyme and pathway design are described.•With AI-guided directed evolution, mutant libraries can be…”
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Deep learning for metabolic pathway design by Ryu, Gahyeon, Kim, Gi Bae, Yu, Taeho, Lee, Sang Yup

“…The establishment of a bio-based circular economy is imperative in tackling the climate crisis and advancing sustainable development. In this realm, the…”
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Designing Microbial Cell Factories for the Production of Chemicals by Cho, Jae Sung, Kim, Gi Bae, Eun, Hyunmin, Moon, Cheon Woo, Lee, Sang Yup

“…The sustainable production of chemicals from renewable, nonedible biomass has emerged as an essential alternative to address pressing environmental issues…”
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Machine learning applications in genome-scale metabolic modeling by Kim, Yeji, Kim, Gi Bae, Lee, Sang Yup

“…Genome-scale metabolic modeling and simulation have been widely employed in biological studies and biotechnological applications due to their powerful…”
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Enhanced production of poly‑3‑hydroxybutyrate (PHB) by expression of response regulator DR1558 in recombinant Escherichia coli by Park, Sung-ho, Kim, Gi Bae, Kim, Hyun Uk, Park, Si Jae, Choi, Jong-il

“…During microbial production of target product, accumulation of by-products and target product itself may be toxic to host strain. Thus, development of abiotic…”
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Metabolic engineering of Corynebacterium glutamicum for the production of glutaric acid, a C5 dicarboxylic acid platform chemical by Kim, Hee Taek, Khang, Tae Uk, Baritugo, Kei-Anne, Hyun, Sung Min, Kang, Kyoung Hee, Jung, Sol Hee, Song, Bong Keun, Park, Kyungmoon, Oh, Min-Kyu, Kim, Gi Bae, Kim, Hyun Uk, Lee, Sang Yup, Park, Si Jae, Joo, Jeong Chan

“…Corynebacterium glutamicum was metabolically engineered for the production of glutaric acid, a C5 dicarboxylic acid that can be used as platform building block…”
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Effect of biologically active fraction of Nardostachys jatamansi on cerulein-induced acute pancreatitis by Bae, Gi-Sang, Kim, Min-Sun, Park, Kyoung-Chel, Koo, Bon Soon, Jo, Il-Joo, Choi, Sun Bok, Lee, Dong-Sung, Kim, Youn-Chul, Kim, Tae-Hyeon, Seo, Sang-Wan, Shin, Yong Kook, Song, Ho-Joon, Park, Sung-Joo

“…AIM： To determine if the fraction of Nardostachysjata- mansi （N J） has the potential to ameliorate the severity of acute pancreatitis （AP）. METHODS： Mice were…”
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Gardeniajasminoides protects against cerulein-induced acute pancreatitis by Won-Seok Jung Jong-Suk Kim Young-Seok Chae Sang-Wan Seo Hee-Je Park Gi-Sang Bae Do-Yun Kim Sung-Yeon Hwang Sung-Joo Park Ho-Joon Song Tae-Hyeon Kim Hyo-Jeong Oh Ki-Jung Yun Rae-Kil Park Eun-Cheol Kim

“…AIM： To investigate the effect of Garden/a fasm/noides （GJ） on cerulein-induced acute pancreatitis （AP） in mice. METHODS： C57BL/6 mice weighing 18-20 g were…”
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