Search Results - "Kim, Elizabeth H"
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Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
Published in Stem cells (Dayton, Ohio) (01-03-2020)“…Cardiac differentiation of embryonic stem cells (ESCs) can give rise to de novo chamber cardiomyocytes and nodal pacemaker cells. Compared with our…”
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2
Pre-existing traits associated with Covid-19 illness severity
Published in PloS one (23-07-2020)“…Certain individuals, when infected by SARS-CoV-2, tend to develop the more severe forms of Covid-19 illness for reasons that remain unclear. To determine the…”
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3
SHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing ability
Published in Stem cell reports (13-01-2015)“…When pluripotency factors are removed, embryonic stem cells (ESCs) undergo spontaneous differentiation, which, among other lineages, also gives rise to cardiac…”
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4
The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions
Published in Breast cancer research and treatment (01-12-2012)“…Women with atypical ductal hyperplasia (ADH), atypical lobular hyperplasia (ALH), lobular carcinoma in situ (LCIS), and severe ADH are at increased risk of…”
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5
Acute neuropathological consequences of short-term mechanical ventilation in wild-type and Alzheimer's disease mice
Published in Critical care (London, England) (22-02-2019)“…Mechanical ventilation is strongly associated with cognitive decline after critical illness. This finding is particularly evident among older individuals who…”
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6
Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study
Published in BMJ open (12-02-2021)“…We sought to determine the extent of SARS-CoV-2 seroprevalence and the factors associated with seroprevalence across a diverse cohort of healthcare workers…”
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Cardiac microstructural alterations in immune-inflammatory myocardial disease: a retrospective case-control study
Published in Cardiovascular ultrasound (04-04-2022)“…Immune-inflammatory myocardial disease contributes to multiple chronic cardiac processes, but access to non-invasive screening is limited. We have previously…”
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Temporal variations in the severity of COVID-19 illness by race and ethnicity
Published in BMJ nutrition, prevention & health (01-06-2021)“…IntroductionEarly reports highlighted racial/ethnic disparities in the severity of COVID-19 seen across the USA; the extent to which these disparities have…”
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Cardiac microstructural alterations measured by echocardiography identify sex-specific risk for heart failure
Published in Heart (British Cardiac Society) (01-11-2022)“…Established preclinical imaging assessments of heart failure (HF) risk are based on macrostructural cardiac remodelling. Given that microstructural alterations…”
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10
Tbx18 Orchestrates Cytostructural Transdifferentiation of Cardiomyocytes to Pacemaker Cells by Recruiting the Epithelial–Mesenchymal Transition Program
Published in Journal of proteome research (07-10-2022)“…Previously, we reported that heterologous expression of an embryonic transcription factor, Tbx18, reprograms ventricular cardiomyocytes into induced pacemaker…”
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11
Augmentation of transgene-encoded protein after neonatal injection of adeno-associated virus improves hepatic copy number without immune responses
Published in Pediatric research (01-09-2015)“…Background: Achieving persistent expression is a prerequisite for genetic therapies for inherited metabolic enzymopathies. Such disorders potentially could be…”
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Novel analysis of 4DCT imaging quantifies progressive increases in anatomic dead space during mechanical ventilation in mice
Published in Journal of applied physiology (1985) (01-09-2017)“…Increased dead space is an important prognostic marker in early acute respiratory distress syndrome (ARDS) that correlates with mortality. The cause of…”
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13
The Use of Polyacrylamide Gel in Soft-Tissue Augmentation: An Experimental Assessment
Published in Plastic and reconstructive surgery (1963) (01-04-2007)“…An increasing number of soft-tissue filler substances that lack experimental and clinical data have been introduced into plastic surgery practice outside the…”
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14
Dasatinib is synergistic with cetuximab and cisplatin in triple-negative breast cancer cells
Published in The Journal of surgical research (01-11-2013)“…Abstract Background Patients presenting with triple-negative breast cancers (TNBCs) have a poorer prognosis compared with those with other subtypes of breast…”
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The feasibility of using natural language processing to extract clinical information from breast pathology reports
Published in Journal of pathology informatics (2012)“…Objective: The opportunity to integrate clinical decision support systems into clinical practice is limited due to the lack of structured, machine readable…”
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Abstract 16912: Cardiac Microstructural Associations With Pulse Pressure Differ by Sex
Published in Circulation (New York, N.Y.) (17-11-2020)“…BackgroundAlterations in the orientation and integrity of myocardial fibers can be assessed using ultrasonic image analysis. The ability to detect such…”
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Abstract 16636: Cardiac Microstructural Associations With Metabolic Syndrome Differ by Sex
Published in Circulation (New York, N.Y.) (17-11-2020)“…BackgroundAlterations in the orientation and integrity of myocardial fibers can be assessed using ultrasonic image analysis. The ability to detect such…”
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Abstract P175: A Twitter Analysis Of Hypertension And Allergies: Discordance Between Social Media Discussion And Disease Morbidity
Published in Hypertension (Dallas, Tex. 1979) (01-09-2020)“…Abstract only Background: Social media data may be used to shed light on how engaged the general public is in conversations surrounding elevated blood pressure…”
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Abstract P167: Leveraging The Electronic Health Records System And Home Blood Pressure Monitoring To Optimize Blood Pressure Control
Published in Hypertension (Dallas, Tex. 1979) (01-09-2020)“…Abstract only Background: Home blood pressure monitoring (HBPM) devices can now be linked to electronic health records (EHR) systems in ways that could be used…”
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Calcium Oscillations in Human Pulmonary Artery Smooth Muscle Cells: Developing a Hierarchical Clustering Method for Analysis and the Effects of IL‐1b
Published in The FASEB journal (01-04-2018)“…Rationale Acute respiratory distress syndrome (ARDS) is characterized by lung inflammation, edema, and severe hypoxemia. In previous work, we showed that IL‐1b…”
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