Search Results - "Kim, Duk Hyoung"
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Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9
Published in Cell stem cell (06-08-2015)“…Hemophilia A is an X-linked genetic disorder caused by mutations in the F8 gene, which encodes the blood coagulation factor VIII. Almost half of all severe…”
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Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome
Published in Molecular cell (02-07-2015)“…Thousands of cis-elements in genomes are predicted to have vital functions. Although conservation, activity in surrogate assays, polymorphisms, and disease…”
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DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins
Published in Scientific reports (28-07-2016)“…Microalgae are versatile organisms capable of converting CO 2 , H 2 O and sunlight into fuel and chemicals for domestic and industrial consumption. Thus,…”
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Site-directed mutagenesis in Petunia × hybrida protoplast system using direct delivery of purified recombinant Cas9 ribonucleoproteins
Published in Plant cell reports (01-07-2016)“…Key message Site-directed mutagenesis of nitrate reductase genes using direct delivery of purified Cas9 protein preassembled with guide RNA produces mutations…”
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Knockout mice created by TALEN-mediated gene targeting
Published in Nature biotechnology (01-01-2013)Get full text
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Precision genome engineering with programmable DNA-nicking enzymes
Published in Genome research (01-07-2012)“…Zinc finger nucleases (ZFNs) are powerful tools of genome engineering but are limited by their inevitable reliance on error-prone nonhomologous end-joining…”
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Cistrome Control of Hematopoieitic Stem/Progenitor Cell Function
Published in Blood (03-12-2015)“…Cis-regulatory mechanisms control chromatin structure and cellular identity. At the GATA2 locus, two cis-elements are linked to human pathologies, including a…”
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Declined Presentation
Published in Experimental hematology (01-08-2014)Get full text
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Declined Presentation: From a hematopoietic stem cell cistrome to novel regulators of hematopoiesis
Published in Experimental hematology (01-08-2014)Get full text
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Declined presentation hematopoietic signaling mechanism revealed from a stem/progenitor cell cistrome
Published in Experimental hematology (01-09-2015)Get full text
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Ball-shaped thrombi in the left ventricular apex
Published in Journal of Cardiovascular Ultrasound (01-09-2011)Get full text
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Ball-shaped thrombi in the left ventricular apex
Published in Journal of cardiovascular ultrasound (01-09-2011)Get full text
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