Search Results - "Kim, Dong Hwee"
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1
Focal adhesion size uniquely predicts cell migration
Published in The FASEB journal (01-04-2013)“…Focal adhesions are large protein complexes organized at the basal surface of cells, which physically connect the extracellular matrix to the cytoskeleton and…”
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2
Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology
Published in Nature communications (14-12-2017)“…The distinct spatial architecture of the apical actin cables (or actin cap) facilitates rapid biophysical signaling between extracellular mechanical stimuli…”
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3
A distinctive role for focal adhesion proteins in three-dimensional cell motility
Published in Nature cell biology (01-06-2010)“…Focal adhesions are large multi-protein assemblies that form at the basal surface of cells on planar dishes, and that mediate cell signalling, force…”
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4
Exosome as a Vehicle for Delivery of Membrane Protein Therapeutics, PH20, for Enhanced Tumor Penetration and Antitumor Efficacy
Published in Advanced functional materials (31-01-2018)“…As biochemical and functional studies of membrane protein remain a challenge, there is growing interest in the application of nanotechnology to solve the…”
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5
Tight coupling between nucleus and cell migration through the perinuclear actin cap
Published in Journal of cell science (01-06-2014)“…Although eukaryotic cells are known to alternate between 'advancing' episodes of fast and persistent movement and 'hesitation' episodes of low speed and low…”
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6
Current status and future direction of metallic and polymeric materials for advanced vascular stents
Published in Progress in materials science (01-05-2022)“…Cardiovascular disease (CVD) has emerged as a severe illness worldwide. Currently, the top ten causes of death in the world include ischemic heart disease…”
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7
Volume regulation and shape bifurcation in the cell nucleus
Published in Journal of cell science (15-09-2015)“…Alterations in nuclear morphology are closely associated with essential cell functions, such as cell motility and polarization, and correlate with a wide range…”
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Dynamic Ligand Screening by Magnetic Nanoassembly Modulates Stem Cell Differentiation
Published in Advanced materials (Weinheim) (01-01-2022)“…In native microenvironment, diverse physical barriers exist to dynamically modulate stem cell recruitment and differentiation for tissue repair. In this study,…”
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Remote Control of Time‐Regulated Stretching of Ligand‐Presenting Nanocoils In Situ Regulates the Cyclic Adhesion and Differentiation of Stem Cells
Published in Advanced materials (Weinheim) (01-03-2021)“…Native extracellular matrix (ECM) can exhibit cyclic nanoscale stretching and shrinking of ligands to regulate complex cell–material interactions. Designing…”
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10
Receptor‐Level Proximity and Fastening of Ligands Modulates Stem Cell Differentiation
Published in Advanced functional materials (01-07-2022)“…Cellular adhesion is regulated by the binding of 10 nm sized integrin to Arg‐Gly‐Asp (RGD) ligands present in extracellular matrix proteins. In this study,…”
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11
Magnetic Control and Real‐Time Monitoring of Stem Cell Differentiation by the Ligand Nanoassembly
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2021)“…Native extracellular matrix (ECM) exhibits dynamic change in the ligand position. Herein, the ECM‐emulating control and real‐time monitoring of stem cell…”
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12
Immunoregulation of Macrophages by Controlling Winding and Unwinding of Nanohelical Ligands
Published in Advanced functional materials (01-09-2021)“…Developing materials with the capability of changing their innate features can help to unravel direct interactions between cells and ligand‐displaying…”
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13
Advanced Immunomodulatory Biomaterials for Therapeutic Applications
Published in Advanced healthcare materials (21-05-2024)“…The multifaceted biological defense system modulating complex immune responses against pathogens and foreign materials plays a critical role in tissue…”
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14
Implantable MicroLED‐Mediated Chemo‐Photodynamic Combination Therapy for Glioma Treatment
Published in Advanced functional materials (01-07-2024)“…Photodynamic therapy shows promise for glioma treatment with powerful efficacy and low resistance, however, its effectiveness is significantly lowered by…”
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15
Injectable Hydrogel-Based Combination Cancer Immunotherapy for Overcoming Localized Therapeutic Efficacy
Published in Pharmaceutics (01-09-2022)“…Various immunotherapeutic agents that can elicit antitumor immune responses have recently been developed with the potential for improved efficacy in treating…”
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16
Recent Studies and Progress in the Intratumoral Administration of Nano-Sized Drug Delivery Systems
Published in Nanomaterials (Basel, Switzerland) (31-07-2023)“…Over the last 30 years, diverse types of nano-sized drug delivery systems (nanoDDSs) have been intensively explored for cancer therapy, exploiting their…”
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Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration
Published in Advanced science (01-04-2024)“…Cell migration interacting with continuously changing microenvironment, is one of the most essential cellular functions, participating in embryonic…”
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18
Mechanobiological Strategies to Enhance Stem Cell Functionality for Regenerative Medicine and Tissue Engineering
Published in Frontiers in cell and developmental biology (03-12-2021)“…Stem cells have been extensively used in regenerative medicine and tissue engineering; however, they often lose their functionality because of the inflammatory…”
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Unraveling the Mechanobiology of the Immune System
Published in Advanced healthcare materials (01-02-2019)“…Cells respond and actively adapt to environmental cues in the form of mechanical stimuli. This extends to immune cells and their critical role in the…”
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In situ blood vessel regeneration using neuropeptide substance P‐conjugated small‐diameter vascular grafts
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-07-2019)“…In situ blood vessel regeneration through host stem/progenitor cell mobilization may hold great promise for vascular reconstruction. Neuropeptide substance P…”
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