Search Results - "Kim, Daria V."

Abasic site–peptide cross-links are blocking lesions repaired by AP endonucleases by Yudkina, Anna V, Bulgakov, Nikita A, Kim, Daria V, Baranova, Svetlana V, Ishchenko, Alexander A, Saparbaev, Murat K, Koval, Vladimir V, Zharkov, Dmitry O

“…Abstract Apurinic/apyrimidinic (AP) sites are abundant DNA lesions arising from spontaneous hydrolysis of the N-glycosidic bond and as base excision repair…”
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Back-Up Base Excision DNA Repair in Human Cells Deficient in the Major AP Endonuclease, APE1 by Kim, Daria V, Diatlova, Evgeniia A, Zharkov, Timofey D, Melentyev, Vasily S, Yudkina, Anna V, Endutkin, Anton V, Zharkov, Dmitry O

“…Apurinic/apyrimidinic (AP) sites are abundant DNA lesions generated both by spontaneous base loss and as intermediates of base excision DNA repair. In human…”
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Probing the Conformational Restraints of DNA Damage Recognition with β-L-Nucleotides by Yudkina, Anna V, Kim, Daria V, Zharkov, Timofey D, Zharkov, Dmitry O, Endutkin, Anton V

“…The DNA building blocks 2'-deoxynucleotides are enantiomeric, with their natural β-D-configuration dictated by the sugar moiety. Their synthetic…”
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Cas9 is mostly orthogonal to human systems of DNA break sensing and repair by Maltseva, Ekaterina A, Vasil'eva, Inna A, Moor, Nina A, Kim, Daria V, Dyrkheeva, Nadezhda S, Kutuzov, Mikhail M, Vokhtantsev, Ivan P, Kulishova, Lilya M, Zharkov, Dmitry O, Lavrik, Olga I

“…CRISPR/Cas9 system is а powerful gene editing tool based on the RNA-guided cleavage of target DNA. The Cas9 activity can be modulated by proteins involved in…”
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Recognition of a Clickable Abasic Site Analog by DNA Polymerases and DNA Repair Enzymes by Endutkin, Anton V., Yudkina, Anna V., Zharkov, Timofey D., Kim, Daria V., Zharkov, Dmitry O.

“…Azide–alkyne cycloaddition (“click chemistry”) has found wide use in the analysis of molecular interactions in living cells…”
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Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line by Kim, Daria V, Kulishova, Liliya M, Torgasheva, Natalia A, Melentyev, Vasily S, Dianov, Grigory L, Medvedev, Sergey P, Zakian, Suren M, Zharkov, Dmitry O

“…The major human apurinic/apyrimidinic (AP) site endonuclease, APEX1, is a central player in the base excision DNA repair (BER) pathway and has a role in the…”
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Base Excision DNA Repair Deficient Cells: From Disease Models to Genotoxicity Sensors by Kim, Daria V, Makarova, Alena V, Miftakhova, Regina R, Zharkov, Dmitry O

“…Base excision DNA repair (BER) is a vitally important pathway that protects the cell genome from many kinds of DNA damage, including oxidation, deamination,…”
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Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides by Endutkin, Anton V, Yudkina, Anna V, Zharkov, Timofey D, Barmatov, Alexander E, Petrova, Daria V, Kim, Daria V, Zharkov, Dmitry O

“…Clickable nucleosides, most often 5-ethynyl-2'-deoxyuridine (EtU), are widely used in studies of DNA replication in living cells and in DNA functionalization…”
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Response of PRIMPOL-Knockout Human Lung Adenocarcinoma A549 Cells to Genotoxic Stress by Gromova, Anastasia S., Boldinova, Elizaveta O., Kim, Daria V., Chuprov-Netochin, Roman N., Leonov, Sergey V., Pustovalova, Margarita V., Zharkov, Dmitry O., Makarova, Alena V.

“…Human DNA primase/polymerase PrimPol synthesizes DNA primers de novo after replication fork stalling at the sites of DNA damage, thus contributing to the DNA…”
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