Search Results - "Kim, Bu Yeo"
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Mumefural Improves Recognition Memory and Alters ERK-CREB-BDNF Signaling in a Mouse Model of Chronic Cerebral Hypoperfusion
Published in Nutrients (24-07-2023)“…Cognitive impairment resulting from chronic cerebral hypoperfusion (CCH) is known as vascular dementia (VaD) and is associated with cerebral atrophy and…”
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The Anti-neuroinflammatory Activity of Tectorigenin Pretreatment via Downregulated NF-κB and ERK/JNK Pathways in BV-2 Microglial and Microglia Inactivation in Mice With Lipopolysaccharide
Published in Frontiers in pharmacology (09-05-2018)“…The activation of microglia is decisively involved with the neurodegeneration observed in many neuroinflammatory pathologies, such as multiple sclerosis,…”
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Elimination of Teratogenic Human Induced Pluripotent Stem Cells by Bee Venom via Calcium-Calpain Pathway
Published in International journal of molecular sciences (05-05-2020)“…Induced pluripotent stem cells (iPSCs) are regarded as a promising option for cell-based regenerative medicine. To obtain safe and efficient iPSC-based cell…”
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Bakuchiol Suppresses Inflammatory Responses Via the Downregulation of the p38 MAPK/ERK Signaling Pathway
Published in International journal of molecular sciences (22-07-2019)“…The purpose of the present study was to evaluate the effects of bakuchiol on the inflammatory response and to identify the molecular mechanism of the…”
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5
Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways
Published in International journal of molecular sciences (01-10-2021)“…p53 is a transcription factor that is activated under DNA damage stress and regulates the expression of proapoptotic genes including the expression of growth…”
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Protease allergen‐induced HMGB1 contributes to NLRC4 inflammasome‐mediated inflammation in experimental asthma
Published in Allergy (Copenhagen) (01-05-2023)Get full text
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Annona atemoya Leaf Extract Improves Scopolamine-Induced Memory Impairment by Preventing Hippocampal Cholinergic Dysfunction and Neuronal Cell Death
Published in International journal of molecular sciences (19-07-2019)“…We explored the preventative effect of leaf (AAL) extract on memory impairment in a scopolamine (SCO)-induced cognitive deficit mouse model. Fifty-eight mice…”
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Diesel exhaust particle exposure exacerbates ciliary and epithelial barrier dysfunction in the multiciliated bronchial epithelium models
Published in Ecotoxicology and environmental safety (15-03-2024)“…Airway epithelium, the first defense barrier of the respiratory system, facilitates mucociliary clearance against inflammatory stimuli, such as pathogens and…”
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Hwangryunhaedok-Tang Exerts Neuropreventive Effect on Memory Impairment by Reducing Cholinergic System Dysfunction and Inflammatory Response in a Vascular Dementia Rat Model
Published in Molecules (Basel, Switzerland) (18-01-2019)“…Hwangryunhaedok-tang (HRT) is a traditional oriental herbal formula used in Asian countries for treating inflammatory diseases and controlling fever. Our…”
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Evaluation of Animal Models by Comparison with Human Late-Onset Alzheimer’s Disease
Published in Molecular neurobiology (01-12-2018)“…Despite many efforts to alleviate the pathological conditions of Alzheimer’s disease (AD), effective therapeutic drugs have not been developed, mainly because…”
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K120R mutation inactivates p53 by creating an aberrant splice site leading to nonsense-mediated mRNA decay
Published in Oncogene (01-03-2019)“…The point mutation that substitutes lysine with arginine at position 120 of human p53 has been characterized as a missense mutation. The K120R mutation renders…”
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12
HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung Tumorigenesis
Published in Cancer research (Chicago, Ill.) (01-03-2016)“…The endothelial-to-mesenchymal transition (EndMT) contributes to cancer, fibrosis, and other pathologic processes. However, the underlying mechanisms are…”
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Extracts of Scutellaria baicalensis Reduced Body Weight and Blood Triglyceride in db/db Mice
Published in Phytotherapy research (01-02-2013)“…Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertension, dysentery, inflammatory…”
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Non-clinical safety assessment of Annona atemoya leaf extract: evaluation of genotoxicity
Published in Toxicological research (Seoul) (01-07-2024)“…The leaves, stems, and fruits of Annona atemoya ( A. atemoya ; AA), a fruit-bearing plant of the family Annonaceae, exhibit anti-angiogenic, anti-oxidative,…”
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Bojungikgi-Tang, a Traditional Herbal Formula, Exerts Neuroprotective Effects and Ameliorates Memory Impairments in Alzheimer's Disease-Like Experimental Models
Published in Nutrients (10-12-2018)“…Bojungikgi-tang (BJIGT; Bu Zhong Yi Qi Tang in China, Hochuekkito in Japan) is a traditional Oriental herbal formula comprised of eight medicinal herbs that…”
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Neuroprotective Effect of Corydalis ternata Extract and Its Phytochemical Quantitative Analysis
Published in Chemical & pharmaceutical bulletin (2017)“…The tubers of Corydalis ternata have been used to treat cardiovascular diseases such as hypertension and cardiac arrhythmia. Its active components have…”
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Helveticoside is a biologically active component of the seed extract of Descurainia sophia and induces reciprocal gene regulation in A549 human lung cancer cells
Published in BMC genomics (18-09-2015)“…Although the pharmacological activities of the seed extract of Descurainia sophia have been proven to be useful against cough, asthma, and edema, the…”
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Simultaneous Determination of the Traditional Herbal Formula Ukgansan and the In Vitro Antioxidant Activity of Ferulic Acid as an Active Compound
Published in Molecules (Basel, Switzerland) (07-07-2018)“…Ukgansan (UGS), a traditional herbal formula composing seven medicinal herbal plants, has been applied in Asian countries for treating neurosis, insomnia, and…”
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Phytochemical Quantification and the In Vitro Acetylcholinesterase Inhibitory Activity of Phellodendron chinense and Its Components
Published in Molecules (Basel, Switzerland) (02-06-2017)“…The dried bark of has been used as a traditional herbal medicine to remove damp heat, relieve consumptive fever, and cure dysentery and diarrhea. In the…”
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Elaeagnus glabra f. oxyphylla Attenuates Scopolamine-Induced Learning and Memory Impairments in Mice by Improving Cholinergic Transmission via Activation of CREB/NGF Signaling
Published in Nutrients (28-05-2019)“…We aimed to investigate the therapeutic effects of an Elaeagnus glabra f. oxyphylla (EGFO) ethanol extract in mice with scopolamine-induced memory dysfunction…”
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