Search Results - "Kim, Bong Hak"

Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1 by Kim, Hak-Bong, Lee, Su-Hoon, Um, Jee-Hyun, Oh, Won Keun, Kim, Dong-Wan, Kang, Chi-Dug, Kim, Sun-Hee

“…The effectiveness of Hsp90 inhibitors as anticancer agents was limited in multidrug-resistant (MDR) human cancer cells due to induction of heat shock proteins…”
Get full text

Potential Role of CD133 Expression in the Susceptibility of Human Liver Cancer Stem-Like Cells to TRAIL by Lee, Su-Hoon, Hyun, Suh-Kyung, Kim, Hak-Bong, Kang, Chi-Dug, Kim, Sun-Hee

“…Hepatocellular carcinoma (HCC) is one of the most common malignancies, with a poor prognosis and high recurrence rate. In the present study, we identified…”
Get full text

Amurensin G, a novel SIRT1 inhibitor, sensitizes TRAIL-resistant human leukemic K562 cells to TRAIL-induced apoptosis by Kim, Hak-Bong, Kim, Mi-Ju, Lee, Su-Hoon, Lee, Jae-Won, Bae, Jae-Ho, Kim, Dong-Wan, Dao, Trong Tuan, Oh, Won Keun, Kang, Chi-Dug, Kim, Sun-Hee

“…Amurensin G, a potent new SIRT1 inhibitor, augmented the effect of TRAIL-mediated apoptosis in TRAIL-resistant human K562 cells by up-regulation of DR5 and…”
Get full text

TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3β pathway and activation of caspases by Seo, Suk-Bin, Hur, Jung-Gu, Kim, Mi-Ju, Lee, Jae-Won, Kim, Hak-Bong, Bae, Jae-Ho, Kim, Dong-Wan, Kang, Chi-Dug, Kim, Sun-Hee

“…BACKGROUND: The development of new modulator possessing high efficacy, low toxicity and high selectivity is a pivotal approach to overcome P-glycoprotein…”
Get full text

A comparative study on effects of static electric field and power frequency electric field on hematology in mice by Di, Guoqing, Gu, Xiaoyu, Lin, Qinhao, Wu, Sixia, Kim, Hak Bong

“…With the development of the ultra high voltage transmission technology, the voltage level of transmission line rised. Accordingly, the strength of electric…”
Get full text

High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde by Kim, Hak-Bong, Kim, Mi-Ju, Kim, Dae-Young, Lee, Jae-Won, Bae, Jae-Ho, Kim, Dong-Wan, Kang, Chi-Dug, Kim, Sun-Hee

“…Tumor recurrence and metastasis develop as a result of tumors' acquisition of anti-apoptotic mechanisms and therefore, it is necessary to develop novel…”
Get full text

Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death by Moon, Hyun-Jung, Kim, Hak-Bong, Lee, Su-Hoon, Jeun, So-Eun, Kang, Chi-Dug, Kim, Sun-Hee

“…NSAIDs (non-steroidal anti-inflammatory drugs) have potential use as anticancer agents, either alone or in combination with other cancer therapies. We found…”
Get full text

Sensitization of chemo-resistant human chronic myeloid leukemia stem-like cells to Hsp90 inhibitor by SIRT1 inhibition by Kim, Hak-Bong, Lee, Su-Hoon, Um, Jee-Hyun, Kim, Mi-Ju, Hyun, Suh-Kyung, Gong, Eun-Ji, Oh, Won Keun, Kang, Chi-Dug, Kim, Sun-Hee

“…Development of effective therapeutic strategies to eliminate cancer stem-like cells (CSCs), which play a major role in drug resistance and disease recurrence,…”
Get full text

Involvement of SIRT1 in hypoxic down-regulation of c-Myc and β-catenin and hypoxic preconditioning effect of polyphenols by Hong, Kyung-Soo, Park, Jun-Ik, Kim, Mi-Ju, Kim, Hak-Bong, Lee, Jae-Won, Dao, Trong Tuan, Oh, Won Keun, Kang, Chi-Dug, Kim, Sun-Hee

“…SIRT1 has been found to function as a Class III deacetylase that affects the acetylation status of histones and other important cellular nonhistone proteins…”
Get full text

Evaluation of Co-C, Ni-C, Re-C and δ(MoC)-C Fixed Points Fabricated at KRISS by Karmalawi, Abdallah Mohamad, Salim, Saber Gomaa Rabie, Yoo, Yong Shim, Soliman, Mohamed Amin, Kim, Bong Hak, Lim, Sun Do

“…This paper presents the recent work that has been carried out at the Korea Research Institute of Standards and Science (KRISS) to fabricate and evaluate high…”
Get full text

Suppression of multidrug resistance by treatment with TRAIL in human ovarian and breast cancer cells with high level of c-Myc by Kim, Dae-Young, Kim, Mi-Ju, Kim, Hak-Bong, Lee, Jae-Won, Bae, Jae-Ho, Kim, Dong-Wan, Kang, Chi-Dug, Kim, Sun-Hee

“…In this study, we investigated the role of c-Myc in overcoming multidrug resistance (MDR) in human ovarian and breast cancer cells by TRAIL. We showed that…”
Get full text

Ku70 acetylation and modulation of c-Myc/ATF4/CHOP signaling axis by SIRT1 inhibition lead to sensitization of HepG2 cells to TRAIL through induction of DR5 and down-regulation of c-FLIP by Kim, Mi-Ju, Hong, Kyung-Soo, Kim, Hak-Bong, Lee, Su-Hoon, Bae, Jae-Ho, Kim, Dong-Wan, Dao, Trong Tuan, Oh, Won Keun, Kang, Chi-Dug, Kim, Sun-Hee

“…In this study, we investigated the role of c-Myc/ATF4/CHOP signaling pathway in sensitization of human hepatoma HepG2 cells to TRAIL. Knockdown of SIRT1 or…”
Get full text

Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway by PARK, Soo-Jung, KIM, Mi-Ju, KIM, Hak-Bong, SOHN, Hee-Young, BAE, Jae-Ho, KANG, Chi-Dug, KIM, Sun-Hee

“…TRAIL-resistant cancer cells can be sensitized to TRAIL by combination therapy. In this study, we investigated the effect of trichostatin A (TSA), a histone…”
Get full text

Cotreatment with apicidin overcomes TRAIL resistance via inhibition of Bcr-Abl signaling pathway in K562 leukemia cells by Park, Soo-Jung, Kim, Mi-Ju, Kim, Hak-Bong, Sohn, Hee-Young, Bae, Jae-Ho, Kang, Chi-Dug, Kim, Sun-Hee

“…TNF-related apoptosis-inducing ligand (TRAIL) is a pro-apoptotic cytokine that is capable of inducing apoptosis in a wide variety of cancer cells but not in…”
Get full text

Sensitization of human K562 leukemic cells to TRAIL-induced apoptosis by inhibiting the DNA-PKcs/Akt-mediated cell survival pathway by Kim, Mi-Ju, Kim, Hak-Bong, Bae, Jae-Ho, Lee, Jae-Won, Park, Soo-Jung, Kim, Dong-Wan, Park, Sang-Ick, Kang, Chi-Dug, Kim, Sun-Hee

“…The mRNA levels of both DR4 and DR5 were significantly increased in K562 cells transfected with DNA-PKcs siRNA compared to the cells transfected with scrambled…”
Get full text

Sensitization of imatinib-resistant CML cells to TRAIL-induced apoptosis is mediated through down-regulation of Bcr-Abl as well as c-FLIP by Park, Soo-Jung, Kim, Mi-Ju, Kim, Hak-Bong, Kang, Chi-Dug, Kim, Sun-Hee

“…Resistance to imatinib is commonly associated with reactivation of Bcr-Abl signalling. However, Bcr-Abl-independent signalling pathways may be activated and…”
Get more information

Construction and Characterization of a Large Aperture Blackbody for Infrared Radiometer Calibration by Park, Chul-Woung, Yoo, Yong Shim, Kim, Bong-Hak, Chun, Sejong, Park, Seung-Nam

“…A large aperture blackbody (LABB) with a diameter of 1 m has been successfully constructed for calibrating radiation thermometers and infrared radiometers with…”
Get full text

Upstream condition effects on the evolution of symmetric and asymmetric near-wakes of a flat plate by Kim, Dong-Ha, Chang, Jo-Won, Kim, Hak-Bong, Sohn, Myong-Hwan

“…An experimental study was conducted in order to investigate the influence of upstream conditions with respect to near-wakes evolution by using a…”
Get full text

Realization of Radiance Temperature Scale from 500K to 1,250K by a Radiation Thermometer with a Thermal Detector by Park, Seung-Nam, Kim, Bong-Hak, Park, Chul-Woung, Lee, Dong-Hoon

“…The radiance temperature scale from 500K to 1,250K was realized by using a thermal detector transfer reference thermometer (TRT) with its spectral response…”
Get full text

Analysis of reverse voltage distribution of high-voltage diode stack considering effect of temperature by Kim, Hak Bong, Ri, In Sik, Kang, Hyon Chol, Ri, Sin Ung, Pak, Yong Taek

“…•“Analysis of Reverse Voltage Distribution of High-Voltage Diode Stack Considering Effect of Temperature” was studied.•The equivalent circuits of high voltage…”
Get full text