Search Results - "Kim, Betty Y.S."

Breaking Down the Barriers to Precision Cancer Nanomedicine by von Roemeling, Christina, Jiang, Wen, Chan, Charles K, Weissman, Irving L, Kim, Betty Y.S

“…Nanomedicine offers unique advantages in treating human cancers. However, physiological and pathological barriers within normal and disease tissues, which are…”
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Waking immune-resistant tumors with neddylation by Huntoon, Kristin, Jiang, Wen, Kim, Betty Ys

“…The CD47/signal regulatory protein α (SIRPα) axis, which functions as an inhibitory phagocytosis checkpoint, also serves as a key mediator in cancer immune…”
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Considerations for designing preclinical cancer immune nanomedicine studies by Jiang, Wen, Wang, Yifan, Wargo, Jennifer A., Lang, Frederick F., Kim, Betty Y. S.

“…Immunotherapy is known to be clinically beneficial for cancer patients and in many cases represents the new standard of care. Because of this success, the…”
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Increased vessel perfusion predicts the efficacy of immune checkpoint blockade by Zheng, Xichen, Fang, Zhaoxu, Liu, Xiaomei, Deng, Shengming, Zhou, Pei, Wang, Xuexiang, Zhang, Chenglin, Yin, Rongping, Hu, Haitian, Chen, Xiaolan, Han, Yijie, Zhao, Yun, Lin, Steven H, Qin, Songbing, Wang, Xiaohua, Kim, Betty Ys, Zhou, Penghui, Jiang, Wen, Wu, Qingyu, Huang, Yuhui

“…Immune checkpoint blockade (ICB) has demonstrated curative potential in several types of cancer, but only for a small number of patients. Thus, the…”
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Low-Dose Anti-Angiogenic Therapy Sensitizes Breast Cancer to PD-1 Blockade by Li, Qian, Wang, Yifan, Jia, Weijuan, Deng, Heran, Li, Guangdi, Deng, Weiye, Chen, Jiewen, Kim, Betty Y S, Jiang, Wen, Liu, Qiang, Liu, Jieqiong

“…Despite its enormous successes, the overall response rate of cancer immunotherapy remains suboptimal, especially in breast cancer. There is an increased…”
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Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes by Qie, Yaqing, Yuan, Hengfeng, von Roemeling, Christina A., Chen, Yuanxin, Liu, Xiujie, Shih, Kevin D., Knight, Joshua A., Tun, Han W., Wharen, Robert E., Jiang, Wen, Kim, Betty Y.S.

“…Nanomedicine is a burgeoning industry but an understanding of the interaction of nanomaterials with the immune system is critical for clinical translation…”
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Immune Priming of the Tumor Microenvironment by Radiation by Jiang, Wen, Chan, Charles K, Weissman, Irving L, Kim, Betty Y S, Hahn, Stephen M

“…Ionizing irradiation can induce a multitude of alterations within the tumor microenvironment. Unlike targeted therapies, radiation delivered to the tumor bed…”
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Visualization of Hepatocellular Regeneration in Mice After Partial Hepatectomy by Chen, Yuanxin, Hata, Toshiyuki, Rehman, Fatima, Kang, Lu, Yang, Liu, Kim, Betty Y.S., Nguyen, Justin H.

“…Although hepatocellular regeneration is the cornerstone of liver homeostasis, current techniques for assessing such regeneration are limited. A method for…”
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Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification by Sun, Lili, Niu, Haoyi, Wu, Yuqiong, Dong, Shiyan, Li, Xuefeng, Kim, Betty Y.S., Liu, Changsheng, Ma, Yifan, Jiang, Wen, Yuan, Yuan

“…Repair of large bone defects caused by severe trauma, non-union fractures, or tumor resection remains challenging because of limited regenerative ability…”
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Membrane TLR9 Positive Neutrophil Mediated MPLA Protects Against Fatal Bacterial Sepsis by Yang, Zhaogang, Wang, Luowei, Yu, Hongmei, Wang, Ruonan, Gou, Yawei, Zhang, MingMing, Kang, Chen, Liu, Tongzheng, Lan, Yu, Wang, Xiaobing, Liu, Jiwei, Cooper, Merideth A, Li, Xin, Yue, Kai, Yu, Yongli, Wang, Liying, Kim, Betty Y S, Jiang, Wen, Sun, Wei

“…Sepsis is a major cause of patient mortality and morbidity from bacterial infections. Although neutrophils are known to be important in the development of…”
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362 Priming of the Brain Tumor Microenvironment Enables Improved Nanomedicine Delivery by Chen, Yuanxin, Jiang, Wen, Qie, Yaqing, Liu, Xiujie, von Roemeling, Christina, Shih, Kevin, Wharen, Robert E., Kim, Betty Y.S.

“…Abstract INTRODUCTION: A major challenge in cancer nanotechnology is the efficient delivery of nanomedicines into solid tumors. Nanomedicine relies on a…”
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Immune landscape of a genetically engineered murine model of glioma compared with human glioma by Zamler, Daniel B, Shingu, Takashi, Kahn, Laura M, Huntoon, Kristin, Kassab, Cynthia, Ott, Martina, Tomczak, Katarzyna, Liu, Jintan, Li, Yating, Lai, Ivy, Zorilla-Veloz, Rocio, Yee, Cassian, Rai, Kunal, Kim, Betty Ys, Watowich, Stephanie S, Heimberger, Amy B, Draetta, Giulio F, Hu, Jian

“…Novel therapeutic strategies targeting glioblastoma (GBM) often fail in the clinic, partly because preclinical models in which hypotheses are being tested do…”
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LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4 by Oue, Hiroshi, Yamazaki, Yu, Qiao, Wenhui, Yuanxin, Chen, Ren, Yingxue, Kurti, Aishe, Shue, Francis, Parsons, Tammee M, Perkerson, Ralph B, Kawatani, Keiji, Wang, Ni, Starling, Skylar C, Roy, Bhaskar, Mosneag, Ioana-Emilia, Aikawa, Tomonori, Holm, Marie-Louise, Liu, Chia-Chen, Inoue, Yasuteru, Sullivan, Patrick M, Asmann, Yan W, Kim, Betty Ys, Bu, Guojun, Kanekiyo, Takahisa

“…Cerebrovasculature is critical in maintaining brain homeostasis; its dysregulation often leads to vascular cognitive impairment and dementia (VCID) during…”
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Engineering a tunable micropattern‐array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ by Zhang, Jingjing, Rima, Xilal Y., Wang, Xinyu, Nguyen, Luong T. H., Huntoon, Kristin, Ma, Yifan, Palacio, Paola Loreto, Nguyen, Kim Truc, Albert, Karunya, Duong‐Thi, Minh‐Dao, Walters, Nicole, Kwak, Kwang Joo, Yoon, Min Jin, Li, Hong, Doon‐Ralls, Jacob, Hisey, Colin L., Lee, Daeyong, Wang, Yifan, Ha, Jonghoon, Scherler, Kelsey, Fallen, Shannon, Lee, Inyoul, Palmer, Andre F., Jiang, Wen, Magaña, Setty M., Wang, Kai, Kim, Betty Y. S., Lee, L. James, Reátegui, Eduardo

“…The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of physically similar particles, such as lipoproteins (LPs), confounds and…”
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Cerebral Venous Thrombosis Associated with Intracranial Hemorrhage and Timing of Anticoagulation after Hemicraniectomy by Pizzi, Michael A., DO, PhD, Alejos, David A., MD, Siegel, Jason L., MD, Kim, Betty Y.S., MD, PhD, Miller, David A., MD, Freeman, William D., MD

“…Background Cerebral venous thrombosis (CVT) is a rare cerebrovascular event that can present with headache, seizure, and focal neurological deficits…”
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Biodegradable Quantum Dot Nanocomposites Enable Live Cell Labeling and Imaging of Cytoplasmic Targets by Kim, Betty Y. S, Jiang, Wen, Oreopoulos, John, Yip, Christopher M, Rutka, James T, Chan, Warren C. W

“…Semiconductor quantum dots (QDs) offer great promise as the new generation of fluorescent probes to image and study biological processes. Despite their…”
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Nanomedicine by Kim, Betty Y.S, Rutka, James T, Chan, Warren C.W

“…Nanotechnology involves the design of structures measuring 1 to 100 nm in diameter. Nanomaterials are being developed as drug-delivery vehicles, contrast…”
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233 Evolutionary Analysis Identifies Early Responsive Macrophage Representing as Anti-tumor Myeloid Cell in Glioblastoma by Zeng, Ailiang, Huntoon, Kristin, Kim, Betty Y.S., Hu, Jian

“…INTRODUCTION: Glioblastoma (GBM) has no effective treatments. Although immunotherapy has shown promise in certain cancer types, it has not been effective…”
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Improving immune–vascular crosstalk for cancer immunotherapy by Huang, Yuhui, Kim, Betty Y. S., Chan, Charles K., Hahn, Stephen M., Weissman, Irving L., Jiang, Wen

“…Normalization of the tumour vasculature can improve immune effector cell infiltration, leading to immunotherapy potentiation. In this Opinion article, Huang et…”
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Phagocytosis checkpoints as new targets for cancer immunotherapy by Feng, Mingye, Jiang, Wen, Kim, Betty Y. S., Zhang, Cheng Cheng, Fu, Yang-Xin, Weissman, Irving L.

“…Cancer immunotherapies targeting adaptive immune checkpoints have substantially improved patient outcomes across multiple metastatic and treatment-refractory…”
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