Search Results - "Kim, Alfred H.J."
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Cardiac Manifestations of Systemic Lupus Erythematosus
Published in Rheumatic diseases clinics of North America (01-02-2014)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that manifests with multiorgan inflammation. Cardiac involvement is common, with…”
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Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know
Published in Annals of internal medicine (02-06-2020)“…Two medications often used for treatment of immune-mediated conditions, hydroxychloroquine and chloroquine, have recently attracted widespread interest as…”
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A Pharmacokinetics‐Informed Approach to Navigating Hydroxychloroquine Shortages in Patients With Rheumatic Disease During the COVID‐19 Pandemic
Published in ACR open rheumatology (01-08-2020)“…Objective The recent hydroxychloroquine (HCQ) shortage due to use in coronavirus disease 2019 (COVID‐19) has forced some rheumatic disease patients to choose…”
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A simple point-of-care assay accurately detects anti-spike antibodies after SARS-CoV-2 vaccination
Published in Journal of clinical virology plus (01-02-2023)“…Lateral flow assays (LFA) are sensitive for detecting antibodies to SARS-CoV-2 proteins within weeks after infection. This study tested samples from…”
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Effect of Immunosuppression on the Immunogenicity of mRNA Vaccines to SARS-CoV-2 : A Prospective Cohort Study
Published in Annals of internal medicine (01-11-2021)“…Patients with chronic inflammatory disease (CID) treated with immunosuppressive medications have increased risk for severe COVID-19. Although mRNA-based…”
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A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19
Published in Annals of internal medicine (16-06-2020)“…Hydroxychloroquine, an essential treatment for many patients with rheumatologic conditions, has recently garnered widespread attention as a potential treatment…”
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From mechanism to therapies in systemic lupus erythematosus
Published in Current opinion in rheumatology (01-03-2017)“…PURPOSE OF REVIEWSystemic lupus erythematosus (SLE) is a disabling and deadly disease. Development of novel therapies for SLE has historically been limited by…”
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The complement system in COVID-19: friend and foe?
Published in JCI insight (06-08-2020)Get full text
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Exploring intentional medication non-adherence in patients with systemic lupus erythematosus: the role of physician–patient interactions
Published in Rheumatology advances in practice (01-01-2021)“…Abstract Objective Medication non-adherence contributes to worse health outcomes among SLE patients. The underlying mechanisms that drive medication…”
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New approaches in renal microscopy: volumetric imaging and superresolution microscopy
Published in Current opinion in nephrology and hypertension (01-05-2016)“…PURPOSE OF REVIEWHistologic and electron microscopic analysis of the kidney has provided tremendous insight into structures such as the glomerulus and nephron…”
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Anxiety Symptoms Among Patients With Systemic Lupus Erythematosus Persist Over Time and Are Independent of SLE Disease Activity
Published in ACR open rheumatology (01-05-2022)“…Objective The objectives of this study are to identify patterns of anxiety symptomology over time among patients with systemic lupus erythematosus (SLE) and to…”
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New roles revealed for T cells and DCs in glomerulonephritis
Published in The Journal of clinical investigation (01-05-2009)“…Little is known about the potential role of T cells in the inflammatory renal disease glomerulonephritis (GN). GN has been historically viewed as a product of…”
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Lupus
Published in Rheumatic diseases clinics of North America (01-08-2021)Get full text
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COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerations
Published in Nature reviews. Rheumatology (01-04-2022)“…The COVID-19 pandemic has brought challenges for people with rheumatic disease in addition to those faced by the general population, including concerns about…”
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The Role of Complement in Autoimmune Disease-Associated Thrombotic Microangiopathy and the Potential for Therapeutics
Published in Journal of rheumatology (01-06-2023)“…The complement system is a tightly regulated, cascading protein network representing a key component linking the innate and humoral immune systems. However, if…”
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Response to SARS-CoV-2 vaccination in immune mediated inflammatory diseases: Systematic review and meta-analysis
Published in Autoimmunity reviews (01-01-2022)“…The treatment for COVID-19 often utilizes immune-modulating drugs. These drugs are also used in immune mediated inflammatory diseases (IMIDs). We performed a…”
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Additional Reassuring Data for SARS-CoV-2 Vaccination in Immune-Mediated Inflammatory Diseases, but With a Catch
Published in Journal of rheumatology (01-04-2024)Get full text
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The complement system in COVID-19: friend and foe?
Published in JCI insight (06-08-2020)“…Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted in a global pandemic and a…”
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Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies
Published in Nature medicine (01-04-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global COVID-19 pandemic. Rapidly spreading SARS-CoV-2 variants may jeopardize…”
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