Search Results - "Kim, Alexia N"
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Late-Stage Diversification: A Motivating Force in Organic Synthesis
Published in Journal of the American Chemical Society (20-10-2021)“…Interest in therapeutic discovery typically drives the preparation of natural product analogs, but these undertakings contribute significant advances for…”
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2
Iridium-catalyzed asymmetric trans -selective hydrogenation of 1,3-disubstituted isoquinolines
Published in Chemical science (Cambridge) (16-03-2022)“…The development of the first asymmetric -selective hydrogenation of 1,3-disubstituted isoquinolines is reported. Utilizing [Ir(cod)Cl] and a commercially…”
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3
Recent Advances in Homogeneous Catalysts for the Asymmetric Hydrogenation of Heteroarenes
Published in ACS catalysis (04-12-2020)“…The asymmetric hydrogenation of heteroarenes has recently emerged as an effective strategy for the direct access to enantioenriched, saturated heterocycles…”
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4
Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002–2020)
Published in Chemical reviews (09-08-2023)“…The tetrahydroisoquinoline (THIQ) natural products constitute one of the largest families of alkaloids and exhibit a wide range of structural diversity and…”
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5
Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines
Published in ACS catalysis (06-03-2020)“…The development of a general method utilizing a hydroxymethyl directing group for asymmetric hydrogenation of 1,3-disubstituted isoquinolines to provide chiral…”
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6
Iridium-catalyzed asymmetric -selective hydrogenation of 1,3-disubstituted isoquinolines
Published in Chemical science (Cambridge) (16-03-2022)“…The development of the first asymmetric trans -selective hydrogenation of 1,3-disubstituted isoquinolines is reported. Utilizing [Ir(cod)Cl] 2 and a…”
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Journal Article