Search Results - "Kim, Alexia"

Recent Advances in Homogeneous Catalysts for the Asymmetric Hydrogenation of Heteroarenes by Kim, Alexia N, Stoltz, Brian M

“…The asymmetric hydrogenation of heteroarenes has recently emerged as an effective strategy for the direct access to enantioenriched, saturated heterocycles…”
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Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002–2020) by Kim, Alexia N., Ngamnithiporn, Aurapat, Du, Emily, Stoltz, Brian M.

“…The tetrahydroisoquinoline (THIQ) natural products constitute one of the largest families of alkaloids and exhibit a wide range of structural diversity and…”
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Iridium-catalyzed asymmetric trans -selective hydrogenation of 1,3-disubstituted isoquinolines by Kim, Alexia N, Ngamnithiporn, Aurapat, Bartberger, Michael D, Stoltz, Brian M

“…The development of the first asymmetric -selective hydrogenation of 1,3-disubstituted isoquinolines is reported. Utilizing [Ir(cod)Cl] and a commercially…”
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Late-Stage Diversification: A Motivating Force in Organic Synthesis by Kim, Kelly E, Kim, Alexia N, McCormick, Carter J, Stoltz, Brian M

“…Interest in therapeutic discovery typically drives the preparation of natural product analogs, but these undertakings contribute significant advances for…”
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Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines by Kim, Alexia N, Ngamnithiporn, Aurapat, Welin, Eric R, Daiger, Martin T, Grünanger, Christian U, Bartberger, Michael D, Virgil, Scott C, Stoltz, Brian M

“…The development of a general method utilizing a hydroxymethyl directing group for asymmetric hydrogenation of 1,3-disubstituted isoquinolines to provide chiral…”
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Investigating Immunomodulatory Biomaterials for Preventing the Foreign Body Response by Kim, Alexia, Downer, Mauricio A, Berry, Charlotte E, Valencia, Caleb, Fazilat, Alex Z, Griffin, Michelle

“…Implantable biomaterials represent the forefront of regenerative medicine, providing platforms and vessels for delivering a creative range of therapeutic…”
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CREEPING FAT-DERIVED FIBROBLASTS PARTICIPATE IN INTESTINAL FIBROSIS IN A NOVEL MOUSE MODEL OF INTESTINAL STRICTURES by Bauer-Rowe, Khristian, Kim, Alexia, Pham, Benjamin, Griffin, Michelle, Norton, Jeffrey, Hyun, Jeong, Longaker, Michael

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CREEPING FAT-DERIVED FIBROBLASTS PARTICIPATE IN INTESTINAL FIBROSIS IN A NOVEL MOUSE MODEL OF INTESTINAL STRICTURES by Bauer-Rowe, Khristian, Kim, Alexia, Pham, Benjamin, Griffin, Michelle, Norton, Jeffrey, Hyun, Jeong, Longaker, Michael

“…Abstract INTRODUCTION An intestinal stricture is a common morbidity in Crohn's disease, but its pathogenesis is poorly understood. CF forms adjacent to…”
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Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin by Foster, Deshka S., Januszyk, Michael, Delitto, Daniel, Yost, Kathryn E., Griffin, Michelle, Guo, Jason, Guardino, Nicholas, Delitto, Andrea E., Chinta, Malini, Burcham, Austin R., Nguyen, Alan T., Bauer-Rowe, Khristian E., Titan, Ashley L., Salhotra, Ankit, Jones, R. Ellen, da Silva, Oscar, Lindsay, Hunter G., Berry, Charlotte E., Chen, Kellen, Henn, Dominic, Mascharak, Shamik, Talbott, Heather E., Kim, Alexia, Nosrati, Fatemeh, Sivaraj, Dharshan, Ransom, R. Chase, Matthews, Michael, Khan, Anum, Wagh, Dhananjay, Coller, John, Gurtner, Geoffrey C., Wan, Derrick C., Wapnir, Irene L., Chang, Howard Y., Norton, Jeffrey A., Longaker, Michael T.

“…Cancer-associated fibroblasts (CAFs) are integral to the solid tumor microenvironment. CAFs were once thought to be a relatively uniform population of…”
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The Role of Tyrosine Kinase Itk in T helper 17 and T regulatory cells in Hypersensitivity Pneumonitis by Elmore, Jessica, Carter, Chavez, Koylass, Nicholas, Bennett, Amelia, Mead, Max, Kim, Alexia, Huang, Weishan, August, Avery

“…Abstract The balance of inflammatory and suppressive cytokines is critical in controlling inflammatory responses, and the pro- and anti-inflammatory cytokines…”
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Where There Is Fat There Is Fibrosis: Elucidating the Mechanisms of Creeping Fat-Driven Stricture Formation by Bauer-Rowe, Khristian E, Kim, Alexia, Griffin, Michelle, Foster, Deshka, Guardino, Nicholas, Guo, Jason L, Talbott, Heather E, Norton, Jeffrey A, Hyun, Jeong S, Longaker, Michael T

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Enantioselective Syntheses of Tetrahydroisoquinolines (Thiqs) Via Iridium-Catalyzed Asymmetric Hydrogenation and Progress Toward the Total Synthesis of (+)-Cyanocycline A by Kim, Alexia Nahyun

“…Described herein are two reviews and three projects related to the asymmetric syntheses of tetrahydroisoquinoline (THIQs) alkaloids, and the progress toward…”
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Iridium-catalyzed asymmetric -selective hydrogenation of 1,3-disubstituted isoquinolines by Kim, Alexia N, Ngamnithiporn, Aurapat, Bartberger, Michael D, Stoltz, Brian M

“…The development of the first asymmetric trans -selective hydrogenation of 1,3-disubstituted isoquinolines is reported. Utilizing [Ir(cod)Cl] 2 and a…”
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