Search Results - "Kim, Albert D."

Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney by Ransick, Andrew, Lindström, Nils O., Liu, Jing, Zhu, Qin, Guo, Jin-Jin, Alvarado, Gregory F., Kim, Albert D., Black, Hannah G., Kim, Junhyong, McMahon, Andrew P.

“…Chronic kidney disease affects 10% of the population with notable differences in ethnic and sex-related susceptibility to kidney injury and disease. Kidney…”
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Proinflammatory Signaling Regulates Hematopoietic Stem Cell Emergence by Espín-Palazón, Raquel, Stachura, David L., Campbell, Clyde A., García-Moreno, Diana, Del Cid, Natasha, Kim, Albert D., Candel, Sergio, Meseguer, José, Mulero, Victoriano, Traver, David

“…Hematopoietic stem cells (HSCs) underlie the production of blood and immune cells for the lifetime of an organism. In vertebrate embryos, HSCs arise from the…”
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Conserved and Divergent Features of Human and Mouse Kidney Organogenesis by Lindström, Nils O, McMahon, Jill A, Guo, Jinjin, Tran, Tracy, Guo, Qiuyu, Rutledge, Elisabeth, Parvez, Riana K, Saribekyan, Gohar, Schuler, Robert E, Liao, Christopher, Kim, Albert D, Abdelhalim, Ahmed, Ruffins, Seth W, Thornton, Matthew E, Baskin, Laurence, Grubbs, Brendan, Kesselman, Carl, McMahon, Andrew P

“…Human kidney function is underpinned by approximately 1,000,000 nephrons, although the number varies substantially, and low nephron number is linked to…”
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Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney by Lindström, Nils O, Guo, Jinjin, Kim, Albert D, Tran, Tracy, Guo, Qiuyu, De Sena Brandine, Guilherme, Ransick, Andrew, Parvez, Riana K, Thornton, Matthew E, Baskin, Laurence, Grubbs, Brendan, McMahon, Jill A, Smith, Andrew D, McMahon, Andrew P

“…Cellular interactions among nephron, interstitial, and collecting duct progenitors drive mammalian kidney development. In mice, Six2 nephron progenitor cells…”
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Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors by Zeng, Zipeng, Huang, Biao, Parvez, Riana K., Li, Yidan, Chen, Jyunhao, Vonk, Ariel C., Thornton, Matthew E., Patel, Tadrushi, Rutledge, Elisabeth A., Kim, Albert D., Yu, Jingying, Grubbs, Brendan H., McMahon, Jill A., Pastor-Soler, Nuria M., Hallows, Kenneth R., McMahon, Andrew P., Li, Zhongwei

“…Current kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney’s collecting duct (CD) system…”
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In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes by Tran, Tracy, Lindström, Nils O., Ransick, Andrew, De Sena Brandine, Guilherme, Guo, Qiuyu, Kim, Albert D., Der, Balint, Peti-Peterdi, Janos, Smith, Andrew D., Thornton, Matthew, Grubbs, Brendan, McMahon, Jill A., McMahon, Andrew P.

“…The renal corpuscle of the kidney comprises a glomerular vasculature embraced by podocytes and supported by mesangial myofibroblasts, which ensure plasma…”
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CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis by Bertrand, Julien Y, Kim, Albert D, Teng, Shutian, Traver, David

“…Development of the vertebrate blood lineages is complex, with multiple waves of hematopoietic precursors arising in different embryonic locations. Monopotent,…”
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A somitic Wnt16/Notch pathway specifies haematopoietic stem cells by Clements, Wilson K., Kim, Albert D., Ong, Karen G., Moore, John C., Lawson, Nathan D., Traver, David

“…Novel pathway specifies haematopoietic stem cells The identification of factors that regulate the earliest steps of haematopoietic stem cell (HSC) formation is…”
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Discrete Notch signaling requirements in the specification of hematopoietic stem cells by Kim, Albert D, Melick, Chase H, Clements, Wilson K, Stachura, David L, Distel, Martin, Panáková, Daniela, MacRae, Calum, Mork, Lindsey A, Crump, J Gage, Traver, David

“…Hematopoietic stem cells (HSCs) require multiple molecular inputs for proper specification, including activity of the Notch signaling pathway. A requirement…”
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Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo by Bertrand, Julien Y, Kim, Albert D, Violette, Emily P, Stachura, David L, Cisson, Jennifer L, Traver, David

“…Shifting sites of blood cell production during development is common across widely divergent phyla. In zebrafish, like other vertebrates, hematopoietic…”
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Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies by O'Brien, Lori L, Guo, Qiuyu, Bahrami-Samani, Emad, Park, Joo-Seop, Hasso, Sean M, Lee, Young-Jin, Fang, Alan, Kim, Albert D, Guo, Jinjin, Hong, Trudy M, Peterson, Kevin A, Lozanoff, Scott, Raviram, Ramya, Ren, Bing, Fogelgren, Ben, Smith, Andrew D, Valouev, Anton, McMahon, Andrew P

“…Nephron progenitor number determines nephron endowment; a reduced nephron count is linked to the onset of kidney disease. Several transcriptional regulators…”
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Jam1a–Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling by Kobayashi, Isao, Kobayashi-Sun, Jingjing, Kim, Albert D., Pouget, Claire, Fujita, Naonobu, Suda, Toshio, Traver, David

“…Notch signalling has a key role in the generation of haematopoietic stem cells (HSCs) during vertebrate development; here two adhesion molecules, Jam1a and…”
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Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter by Kim, Albert D., Lake, Blue B., Chen, Song, Wu, Yan, Guo, Jinjin, Parvez, Riana K., Tran, Tracy, Thornton, Matthew E., Grubbs, Brendan, McMahon, Jill A., Zhang, Kun, McMahon, Andrew P.

“…Analysis of kidney disease-causing genes and pathology resulting from systemic diseases highlight the importance of the kidney's filtering system, the renal…”
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Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis by Lindström, Nils O., De Sena Brandine, Guilherme, Tran, Tracy, Ransick, Andrew, Suh, Gio, Guo, Jinjin, Kim, Albert D., Parvez, Riana K., Ruffins, Seth W., Rutledge, Elisabeth A., Thornton, Matthew E., Grubbs, Brendan, McMahon, Jill A., Smith, Andrew D., McMahon, Andrew P.

“…Mammalian nephrons arise from a limited nephron progenitor pool through a reiterative inductive process extending over days (mouse) or weeks (human) of kidney…”
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Spatial transcriptional mapping of the human nephrogenic program by Lindström, Nils O., Sealfon, Rachel, Chen, Xi, Parvez, Riana K., Ransick, Andrew, De Sena Brandine, Guilherme, Guo, Jinjin, Hill, Bill, Tran, Tracy, Kim, Albert D., Zhou, Jian, Tadych, Alicja, Watters, Aaron, Wong, Aaron, Lovero, Elizabeth, Grubbs, Brendan H., Thornton, Matthew E., McMahon, Jill A., Smith, Andrew D., Ruffins, Seth W., Armit, Chris, Troyanskaya, Olga G., McMahon, Andrew P.

“…Congenital abnormalities of the kidney and urinary tract are among the most common birth defects, affecting 3% of newborns. The human kidney forms around a…”
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Cell signaling pathways involved in hematopoietic stem cell specification by Kim, Albert D., Stachura, David L., Traver, David

“…•Generation of hematopoietic stem cells is a pressing goal for regenerative medicine.•The ontogeny of the hematopoietic system proceeds through multiple…”
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FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling by Lee, Yoonsung, Manegold, Jennifer E., Kim, Albert D., Pouget, Claire, Stachura, David L., Clements, Wilson K., Traver, David

“…Haematopoietic stem cells (HSCs) derive from haemogenic endothelial cells of the primitive dorsal aorta (DA) during vertebrate embryogenesis. The molecular…”
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Correction: A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells by Guo, Qiuyu, Kim, Albert D, Li, Bin, Ransick, Andrew, Bugacov, Helena, Chen, Xi, Lindström, Nils O, Brown, Aaron, Oxburgh, Leif, Ren, Bing, McMahon, Andrew P

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Correction: A [beta]-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells by Guo, Qiuyu, Kim, Albert D, Li, Bin, Ransick, Andrew, Bugacov, Helena, Chen, Xi, Lindström, Nils O, Brown, Aaron, Oxburgh, Leif, Ren, Bing, McMahon, Andrew P

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In vivo developmental trajectories of human podocyte development inform in vitro differentiation of pluripotent stem-cell derived podocytes by Tran, Tracy, Lindström, Nils O., Ransick, Andrew, Brandine, Guilherme De Sena, Guo, Qiuyu, Kim, Albert D., Der, Balint, Peti-Peterdi, Janos, Smith, Andrew D., Thornton, Matthew, Grubbs, Brendan, McMahon, Jill A., McMahon, Andrew P.

“…The renal corpuscle of the kidney comprises a glomerular vasculature embraced by podocytes and supported by mesangial myofibroblasts, which ensure plasma…”
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