Search Results - "Kim, Aeyung"

Isoliquiritin Apioside Suppresses in vitro Invasiveness and Angiogenesis of Cancer Cells and Endothelial Cells by Kim, Aeyung, Ma, Jin Yeul

“…Several components isolated from (GR), including glycyrrhizin, liquiritin, and liquiritigenin, have been shown to induce cancer cell death and inhibit cancer…”
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Systems pharmacology approaches in herbal medicine research: a brief review by Lee, Myunggyo, Shin, Hyejin, Park, Musun, Kim, Aeyung, Cha, Seongwon, Lee, Haeseung

“…Herbal medicine, a multi-component treatment, has been extensively practiced for treating various symptoms and diseases. However, its molecular mechanism of…”
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SRVF, a novel herbal formula including Scrophulariae Radix and Viticis Fructus, disrupts focal adhesion and causes detachment-induced apoptosis in malignant cancer cells by Kim, Aeyung, Im, Minju, Ma, Jin Yeul

“…When cells lose adhesion, they undergo detachment-induced apoptosis, known as anoikis. In contrast, tumor cells acquire resistance to anoikis, enabling them to…”
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Citrus unshiu peel extract alleviates cancer-induced weight loss in mice bearing CT-26 adenocarcinoma by Kim, Aeyung, Im, Minju, Gu, Min Jung, Ma, Jin Yeul

“…Skeletal muscle atrophy is a critical feature of cancer-induced cachexia, caused by pro-cachectic factors secreted by host cells and tumor cells. Therefore,…”
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Astragalus Complanatus Ethanol Attenuates Septic Shock by Exerting Anti-Inflammatory Effects on Macrophages by Hwang, Yo Sep, Lim, Jeewon, Yoon, Hyang Ran, Park, Seong-Hoon, Kim, Aeyung, Jang, Jun-Pil, Cho, Hee Jun, Lee, Hee Gu

“…Sepsis is a systemic inflammatory syndrome that results in multiple-organ failure caused by a dysregulated host immune response to microbial infection…”
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Reduction of metastatic and angiogenic potency of malignant cancer by Eupatorium fortunei via suppression of MMP-9 activity and VEGF production by Kim, Aeyung, Im, Minju, Yim, Nam-Hui, Ma, Jin Yeul

“…Eupatorium fortunei has long been used to treat nausea and poor appetite and has been prescribed as a diuretic and detoxifying drug in Chinese medicine. Recent…”
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Identification of a novel anticancer mechanism of Paeoniae Radix extracts based on systematic transcriptome analysis by Baek, Su-Jin, Lee, Haeseung, Park, Sang-Min, Park, Musun, Yi, Jin-Mu, Kim, No Soo, Kim, Aeyung, Cha, Seongwon

“…Paeoniae Radix (PR) has a great therapeutic value in many clinical applications; however, the presence of various bioactive compounds and its complicated…”
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Elimination of Teratogenic Human Induced Pluripotent Stem Cells by Bee Venom via Calcium-Calpain Pathway by Kim, Aeyung, Lee, Seo-Young, Kim, Bu-Yeo, Chung, Sun-Ku

“…Induced pluripotent stem cells (iPSCs) are regarded as a promising option for cell-based regenerative medicine. To obtain safe and efficient iPSC-based cell…”
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Ginsenoside Rc, an Active Component of Panax ginseng, Alleviates Oxidative Stress-Induced Muscle Atrophy via Improvement of Mitochondrial Biogenesis by Kim, Aeyung, Park, Sang-Min, Kim, No Soo, Lee, Haeseung

“…Loss of skeletal muscle mass and function has detrimental effects on quality of life, morbidity, and mortality, and is particularly relevant in aging…”
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KORE-Map 1.0: Korean medicine Omics Resource Extension Map on transcriptome data of tonifying herbal medicine by Park, Musun, Park, Sang-Min, Lee, Haeseung, Kim, Aeyung, Kim, No Soo, Kim, Yu Ri, Yi, Jin-Mu, Cha, Seongwon

“…Traditional herbal medicine, rooted in a long history of use in East Asia, combines several herbs to create treatments showing high efficacy with minimal side…”
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Systematic transcriptome analysis reveals molecular mechanisms and indications of bupleuri radix by Park, Sang-Min, Kim, Aeyung, Lee, Haeseung, Baek, Su-Jin, Kim, No Soo, Park, Musun, Yi, Jin-Mu, Cha, Seongwon

“…Pharmacogenomic analysis based on drug transcriptomic signatures is widely used to identify mechanisms of action and pharmacological indications. Despite…”
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Prunellae Spica Extract Suppresses Teratoma Formation of Pluripotent Stem Cells through p53-Mediated Apoptosis by Kim, Aeyung, Lee, Seo-Young, Seo, Chang-Seob, Chung, Sun-Ku

“…Induced pluripotent stem cells (iPSCs) have similar properties to embryonic stem cells in terms of indefinite self-renewal and differentiation capacity. After…”
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An Ethanol Extract of Coptidis rhizoma Induces Apoptotic Cell Death in Induced Pluripotent Stem Cells and Suppresses Teratoma Formation by Kim, Aeyung, Baek, Su-Jin, Shin, Sarah, Lee, Seo-Young, Chung, Sun-Ku

“…In cell-based regenerative medicine, induced pluripotent stem cells (iPSCs) generated from reprogrammed adult somatic cells have emerged as a useful cell…”
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Jaeumganghwa-Tang Induces Apoptosis via the Mitochondrial Pathway and Lactobacillus Fermentation Enhances Its Anti-Cancer Activity in HT1080 Human Fibrosarcoma Cells by Kim, Aeyung, Im, Minju, Hwang, Youn-Hwan, Yang, Hye Jin, Ma, Jin Yeul

“…Jaeumganghwa-tang (JGT, Zi-yin-jiang-huo-tang in Chinese and Jiin-koka-to in Japanese) is an oriental herbal formula that has long been used as a traditional…”
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Sosiho-tang ameliorates cachexia-related symptoms in mice bearing colon 26 adenocarcinoma by reducing systemic inflammation and muscle loss by KIM, AEYUNG, IM, MINJU, MA, JIN YEUL

“…Cachexia accompanied by muscle wasting is a key determinant of poor prognosis in cancer patients and cancer-related death. Previous studies have demonstrated…”
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A novel herbal medicine, KIOM-C, induces autophagic and apoptotic cell death mediated by activation of JNK and reactive oxygen species in HT1080 human fibrosarcoma cells by Kim, Aeyung, Im, Minju, Yim, Nam-Hui, Kim, Taesoo, Ma, Jin Yeul

“…KIOM-C was recently demonstrated to have anti-metastatic activity in highly malignant cancer cells via suppression of NF-κB-mediated MMP-9 activity. In…”
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Aqueous extract of Bambusae Caulis in Taeniam inhibits PMA-induced tumor cell invasion and pulmonary metastasis: suppression of NF-κB activation through ROS signaling by Kim, Aeyung, Im, Minju, Yim, Nam-Hui, Jung, Young Pil, Ma, Jin Yeul

“…Bamboo shavings (Bambusae Caulis in Taeniam, BCT) are widely used as a traditional Chinese medicine to control hypertension and cardiovascular disease, and to…”
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Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells by Shon, Soo-Kyung, Kim, Aeyung, Kim, Ji Young, Kim, Keun Il, Yang, Young, Lim, Jong-Seok

“…In the current study, we examined the function of N-myc downstream-regulated gene 2 (NDRG2) expression in breast cancer cells, especially focusing on the role…”
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Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide by Kim, Aeyung, Shin, Tae-Hwan, Shin, Seung-Min, Pham, Chuong D, Choi, Dong-Ki, Kwon, Myung-Hee, Kim, Yong-Sung

“…Cellular internalization of bacteriophage by surface-displayed cell penetrating peptides has been reported, though the underlying mechanism remains elusive…”
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Magnoliae Cortex (EEMC) limits teratoma formation of pluripotent stem cells by selective killing of undifferentiated cells through the p53-dependent mitochondrial apoptotic pathway by Kim, Aeyung, Lee, Seo-Young, Chung, Sun-Ku

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