Search Results - "Kim, Aeryun"
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Helicobacter pylori-mediated gastric pathogenesis is attenuated by treatment of 2-deoxyglucose and metformin
Published in The journal of microbiology (01-08-2022)“…Helicobacter pylori infection causes chronic inflammation in the stomach, which is linked to the development of gastric cancer. The anti-inflammatory and…”
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2
Evolutionary mechanism leading to the multi-cagA genotype in Helicobacter pylori
Published in Scientific reports (01-08-2019)“…Infection with CagA+ Helicobacter pylori strains is linked to an increased risk for gastric diseases, including gastric cancer. Recent evidence indicates that…”
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3
Comparative analysis of the Hom family of outer membrane proteins in isolates from two geographically distinct regions: The United States and South Korea
Published in Helicobacter (Cambridge, Mass.) (01-04-2018)“…Background Helicobacter pylori encodes numerous outer membrane proteins (OMPs), but only a few have been characterized in depth. Deletion, duplication, and…”
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4
ArsRS-Dependent Regulation of homB Contributes to Helicobacter pylori Biofilm Formation
Published in Frontiers in microbiology (02-08-2018)“…One elusive area in the field is an understanding of why some infections result in gastric cancer, yet others persist asymptomatically for the life-span of the…”
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5
CagL polymorphisms between East Asian and Western Helicobacter pylori are associated with different abilities to induce IL-8 secretion
Published in The journal of microbiology (01-08-2021)“…Helicobacter pylori colonizes human gastric mucosa. Its infection is associated with gastric diseases including gastric cancer. CagA is one of the most…”
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6
Intermittent PTH administration improves alveolar bone formation in type 1 diabetic rats with periodontitis
Published in Journal of translational medicine (15-03-2018)“…Periodontitis is an infectious disease that manifests as alveolar bone loss surrounding the roots of teeth. Diabetes aggravates periodontitis-induced alveolar…”
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7
Geographic diversity in Helicobacter pylori oipA genotype between Korean and United States isolates
Published in The journal of microbiology (01-12-2021)“…Helicobacter pylori outer membrane inflammatory protein A (OipA) was originally named for its role in inducing inflammation in the host, as evidenced by high…”
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8
Characterization of East-Asian Helicobacter pylori encoding Western EPIYA-ABC CagA
Published in The journal of microbiology (01-02-2022)“…The polymorphic bacterial oncoprotein, CagA shows geography-dependent variation in the C-terminal Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs; East-Asian H. pylori…”
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9
Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis
Published in Journal of translational medicine (09-11-2018)“…Diabetes induces long bone loss and aggravation of periodontitis-induced alveolar bone loss. Simvastatin (SIM), which is a lipid-lowering agent is known to…”
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10
Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical Isolates
Published in PloS one (28-08-2015)“…Helicobacter pylori genetic variation is a crucial component of colonization and persistence within the inhospitable niche of the gastric mucosa. As such,…”
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11
TRPC expression in human periodontal ligament cells and the periodontal tissue of periodontitis mice: a preliminary study
Published in Laboratory animal research (01-09-2023)“…Abstract Background Transient receptor potential canonical (TRPC) channels are non-selective cationic channels with permeability to Ca 2+ and Na + . Despite…”
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12
Helicobacter pylori -Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway
Published in Frontiers in cellular and infection microbiology (15-01-2018)“…is associated with hypergastrinemia, which has been linked to the development of gastric diseases. Although the molecular mechanism is not fully understood, is…”
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Correction: Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical Isolates
Published in PloS one (2017)“…[This corrects the article DOI: 10.1371/journal.pone.0137078.]…”
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14
Helicobacter pylori outer membrane protein, HomC, shows geographic dependent polymorphism that is influenced by the Bab family
Published in The journal of microbiology (01-12-2016)“…The array of outer membrane proteins (OMPs) found in Helicobacter pylori provides a crucial component for persistent colonization within the gastric niche. Not…”
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15
Role of bacterial γ-glutamyltranspeptidase as a novel virulence factor in bone-resorbing pathogenesis
Published in The journal of microbiology (01-05-2016)“…Mammalian γ-glutamyltranspeptidase (GGT) has been identified as a bone-resorbing factor. Since GGT of Bacillus subtilis exhibits similarity in their primary…”
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16
Effect of Areca Nut on Helicobacter pylori -Induced Gastric Diseases in Mice
Published in Journal of microbiology and biotechnology (28-10-2016)“…Areca nut (AN) chewing is a habit in many countries in Central, Southern, and Southeast Asia. It is strongly associated with the occurrence of oral,…”
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Effect of Areca Nut on Helicobacter pylori-Induced Gastric Diseases in Mice
Published in Journal of microbiology and biotechnology (31-10-2016)“…Areca nut (AN) chewing is a habit in many countries in Central, Southern, and Southeast Asia. It is strongly associated with the occurrence of oral,…”
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18
Influence of oipA Phase Variation on Virulence Phenotypes Related to Type IV Secretion System in Helicobacter pylori
Published in Helicobacter (Cambridge, Mass.) (01-09-2024)“…ABSTRACT Background oipA, an outer membrane protein of Helicobacter pylori, is linked to IL‐8 induction and gastric inflammation, but its role is debated due…”
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Dynamic Expansion and Contraction of cagA Copy Number in Helicobacter pylori Impact Development of Gastric Disease
Published in mBio (21-02-2017)“…Infection with is a major risk factor for development of gastric disease, including gastric cancer. Patients infected with strains that express CagA are at…”
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20
Role of bacterial [gamma]-glutamyltranspeptidase as a novel virulence factor in bone-resorbing pathogenesis
Published in The journal of microbiology (01-05-2016)“…Mammalian γ-glutamyltranspeptidase (GGT) has been identified as a bone-resorbing factor. Since GGT of Bacillus subtilis exhibits similarity in their primary…”
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