Search Results - "Kim, A. Yoon"
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Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology
Published in Neurobiology of disease (01-08-2022)“…Alzheimer's disease (AD) is the most prevalent neurodegenerative disease placing a great burden on people living with it, carers and society. Yet, the…”
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Human Stem Cell-Derived Spinal Cord Astrocytes with Defined Mature or Reactive Phenotypes
Published in Cell reports (Cambridge) (12-09-2013)“…Differentiation of astrocytes from human stem cells has significant potential for analysis of their role in normal brain function and disease, but existing…”
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Marked Mild Cognitive Deficits in Humanized Mouse Model of Alzheimer’s-Type Tau Pathology
Published in Frontiers in behavioral neuroscience (21-05-2021)“…Hyperphosphorylation and the subsequent aggregation of tau protein into neurofibrillary tangles (NFTs) are well-established neuropathological hallmarks of…”
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Hybrid numerical modeling of ballistic clay under low-speed impact using artificial neural network
Published in Journal of mechanical science and technology (01-02-2023)“…Roma Plastilina No. 1 clay has been widely used as a conservative boundary condition in bulletproof vests, namely to play the role of a human body…”
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Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures
Published in PloS one (22-10-2014)“…Human motor neurons derived from embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are a potentially important tool for studying motor neuron…”
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PKCι is a target of 7,8,4′‐trihydroxyisoflavone for the suppression of UVB‐induced MMP‐1 expression
Published in Experimental dermatology (01-05-2018)“…The soy isoflavone daidzein is bioconverted to 7,8,4′‐trihydroxyisoflavone (7,8,4′‐THIF) by microorganisms. Here, we investigated the matrix metalloproteinase…”
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4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions
Published in Food science and human wellness (01-07-2023)“…Many approaches to neurodegenerative diseases that focus on amyloid-β clearance and gene therapy have not been successful. Some therapeutic applications focus…”
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Co-regulation of ocular dominance plasticity and NMDA receptor subunit expression in glutamic acid decarboxylase-65 knock-out mice
Published in The Journal of physiology (15-06-2009)“…Experience can shape cortical circuits, especially during critical periods for plasticity. In visual cortex, imbalance of activity from the two eyes during the…”
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Mechanisms linking cerebrovascular dysfunction and tauopathy: Adding a layer of epiregulatory complexity
Published in British journal of pharmacology (01-03-2024)“…Intracellular accumulation of hyperphosphorylated misfolded tau proteins are found in many neurodegenerative tauopathies, including Alzheimer's disease (AD)…”
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Cohort Profile: The Registry-based Epidemiological Study of Cancer in Fire Unit and Emergency Officers (RESCUE) cohort
Published in International journal of epidemiology (13-10-2024)Get full text
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Admixture Mapping of Alzheimer’s disease in Caribbean Hispanics identifies a new locus on 22q13.1
Published in Molecular psychiatry (01-06-2022)“…Late-onset Alzheimer’s disease (LOAD) is significantly more frequent in Hispanics than in non-Hispanic Whites. Ancestry may explain these differences across…”
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RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation
Published in Acta neuropathologica (01-01-2023)“…Epitranscriptomic regulation adds a layer of post-transcriptional control to brain function during development and adulthood. The identification of…”
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Empirical and numerical study on Roma Plastilina #1 ballistic clay under various drop impact tests
Published in Mechanics of advanced materials and structures (17-09-2023)“…The ballistic clay is used to assess protection performance of bulletproof vests. Applying a clay block behind targets conservatively provides similar behavior…”
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Comparison of volumetric and shape changes of subcortical structures based on 3-dimensional image between obesity and normal-weighted subjects using 3.0 T MRI
Published in Journal of clinical neuroscience (01-03-2020)“…•Obese subjects had enlarged thalamus volumes and reduced caudate volumes.•The medial-dorsal part of bilateral caudate significantly shrank.•The lateral-dorsal…”
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Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
Published in Cell stem cell (02-05-2024)“…Frontotemporal dementia (FTD) is an incurable group of early-onset dementias that can be caused by the deposition of hyperphosphorylated tau in patient brains…”
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Evaluating the Stability of Locking Screw on Locking Compression Plate According to Various Screw Insertion Angles
Published in International journal of precision engineering and manufacturing (01-07-2022)“…Humeral shaft fracture is one of the most common fractures in older adults. For humeral shaft fractures, a fixed treatment is performed using a straight plate…”
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Characterization of a Multimodular Endo-β-1,4-Glucanase (Cel9K) from Paenibacillus sp. X4 with a Potential Additive for Saccharification
Published in Journal of microbiology and biotechnology (01-04-2018)“…An endo-β-1,4-glucanase gene, 9K, was cloned using the shot-gun method from sp. X4, which was isolated from alpine soil. The gene was 2,994 bp in length,…”
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Rutin inhibits B[a]PDE-induced cyclooxygenase-2 expression by targeting EGFR kinase activity
Published in Biochemical pharmacology (15-11-2013)“…Rutin is a well-known flavonoid that exists in various natural sources. Accumulative studies have represented the biological effects of rutin, such as…”
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The atopic dermatitis-like symptoms induced by MC903 were alleviated in JNK1 knockout mice
Published in Toxicological sciences (01-12-2013)“…Atopic dermatitis (AD) is a common allergic disease, imposing large social and economic burdens worldwide. Atopic dermatitis is characterized by eczematous…”
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Quantizer Design for Energy-Based Source Localization in Sensor Networks
Published in IEEE transactions on signal processing (01-11-2011)“…We consider energy-based source localization applications, where distributed sensors quantize acoustic signal energy readings and transmit quantized data to a…”
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