Search Results - "Kilpatrick, L."

GABAA receptor trafficking-mediated plasticity of inhibitory synapses by Luscher, Bernhard, Fuchs, Thomas, Kilpatrick, Casey L

“…Proper developmental, neural cell-type-specific, and activity-dependent regulation of GABAergic transmission is essential for virtually all aspects of CNS…”
Get full text

Marine Cyanobacteria and Microalgae Metabolites-A Rich Source of Potential Anticancer Drugs by Mondal, Arijit, Bose, Sankhadip, Banerjee, Sabyasachi, Patra, Jayanta Kumar, Malik, Jai, Mandal, Sudip Kumar, Kilpatrick, Kaitlyn L, Das, Gitishree, Kerry, Rout George, Fimognari, Carmela, Bishayee, Anupam

“…Cancer is at present one of the utmost deadly diseases worldwide. Past efforts in cancer research have focused on natural medicinal products. Over the past…”
Get full text

Amygdala modulation of parahippocampal and frontal regions during emotionally influenced memory storage by Kilpatrick, Lisa, Cahill, Larry

“…Considerable evidence from both animal and human subject research supports the hypothesis that the amygdala, when activated by emotional arousal, modulates…”
Get full text

Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy by Ghanbari-Movahed, Maryam, Ghanbari-Movahed, Zahra, Momtaz, Saeideh, Kilpatrick, Kaitlyn L, Farzaei, Mohammad Hosein, Bishayee, Anupam

“…The dysregulation of Notch signaling is associated with a wide variety of different human cancers. Notch signaling activation mostly relies on the activity of…”
Get full text

Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear by Kilpatrick, L A, Li, Q, Yang, J, Goddard, J C, Fekete, D M, Lang, H

“…Murine models are ideal for studying cochlear gene transfer, as many hearing loss-related mutations have been discovered and mapped within the mouse genome…”
Get full text

Quantifying Target Occupancy of Small Molecules Within Living Cells by Robers, M.B, Friedman-Ohana, R, Huber, K.V.M, Kilpatrick, L, Vasta, J.D, Berger, B.-T, Chaudhry, C, Hill, S, Müller, S, Knapp, S, Wood, K.V

“…The binding affinity and kinetics of target engagement are fundamental to establishing structure-activity relationships (SARs) for prospective therapeutic…”
Get full text

Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation by Hong, J.‐Y., Naliboff, B., Labus, J. S., Gupta, A., Kilpatrick, L. A., Ashe‐McNalley, C., Stains, J., Heendeniya, N., Smith, S. R., Tillisch, K., Mayer, E. A.

“…Background A majority of the subjects with irritable bowel syndrome (IBS) show increased behavioral and brain responses to expected and delivered aversive…”
Get full text

Health System and Individual Barriers to Supporting Healthy Gestational Weight Gain and Nutrition: A Qualitative Study of the Experiences of Midwives and Obstetricians in Publicly Funded Antenatal Care in Tasmania, Australia by Kilpatrick, Michelle L, Venn, Alison J, Barnden, Kristine R, Newett, Kristy, Harrison, Cheryce L, Skouteris, Helen, Hills, Andrew P, Hill, Briony, Lim, Siew S, Jose, Kim A

“…Individual and health system barriers can impede clinicians from supporting weight-related behaviour change for pregnant women, particularly in publicly funded…”
Get full text

Aconitate decarboxylase 1 suppresses cerebral ischemia-reperfusion injury in mice by Vigil, Thomas M., Frieler, Ryan A., Kilpatrick, KiAundra L., Wang, Michael M., Mortensen, Richard M.

“…Immunometabolic changes have been shown to be a key factor in determining the immune cell response in disease models. The immunometabolite, itaconate, is…”
Get full text

Resilience is decreased in irritable bowel syndrome and associated with symptoms and cortisol response by Park, S. H., Naliboff, B. D., Shih, W., Presson, A. P., Videlock, E. J., Ju, T., Kilpatrick, L., Gupta, A., Mayer, E. A., Chang, L.

“…Background Irritable bowel syndrome (IBS) is a stress‐sensitive disorder associated with early adverse life events (EALs) and a dysregulated…”
Get full text

Selective Clearance of Macrophages in Atherosclerotic Plaques by Autophagy by Verheye, Stefan, MD, PhD, Martinet, Wim, PhD, Kockx, Mark M., MD, PhD, Knaapen, Michiel W.M., PhD, Salu, Koen, MD, PhD, Timmermans, Jean-Pierre, PhD, Ellis, Jeffrey T., PhD, Kilpatrick, Deborah L., PhD, De Meyer, Guido R.Y., PharMD, PhD

“…Selective Clearance of Macrophages in Atherosclerotic Plaques by Autophagy Stefan Verheye, Wim Martinet, Mark M. Kockx, Michiel W. M. Knaapen, Koen Salu,…”
Get full text

Separation of monosaccharides hydrolyzed from glycoproteins without the need for derivatization by Lowenthal, Mark S, Kilpatrick, Eric L, Phinney, Karen W

“…Chromatographic separation of monosaccharides hydrolyzed from glycoconjugates or complex, aggregate biomaterials, can be achieved by classic analytical methods…”
Get full text

Acute tryptophan depletion alters the effective connectivity of emotional arousal circuitry during visceral stimuli in healthy women by Labus, J S, Mayer, E A, Jarcho, J, Kilpatrick, L A, Kilkens, T O C, Evers, E A T, Backes, W H, Brummer, R-J M, van Nieuwenhoven, M A

“…Alterations in serotonin signalling within the brain-gut axis have been implicated in the pathophysiology of irritable bowel syndrome (IBS) and is a treatment…”
Get more information

Sex-related differences in amygdala functional connectivity during resting conditions by Kilpatrick, L.A., Zald, D.H., Pardo, J.V., Cahill, L.F.

“…Recent neuroimaging studies have established a sex-related hemispheric lateralization of amygdala involvement in memory for emotionally arousing material…”
Get full text

Differences in brain responses between lean and obese women to a sweetened drink by Connolly, L., Coveleskie, K., Kilpatrick, L. A., Labus, J. S., Ebrat, B., Stains, J., Jiang, Z., Tillisch, K., Raybould, H. E., Mayer, E. A.

“…Background Ingestion of sweet food is driven by central reward circuits and restrained by endocrine and neurocrine satiety signals. The specific influence of…”
Get full text

Quantitative analysis of neuropeptide Y receptor association with β‐arrestin2 measured by bimolecular fluorescence complementation by Kilpatrick, LE, Briddon, SJ, Hill, SJ, Holliday, ND

“…Background and purpose:  β‐Arrestins are critical scaffold proteins that shape spatiotemporal signalling from seven transmembrane domain receptors (7TMRs)…”
Get full text

Brain networks associated with cognitive and hedonic responses to a meal by Pribic, T., Kilpatrick, L., Ciccantelli, B., Malagelada, C., Accarino, A., Rovira, A., Pareto, D., Mayer, E., Azpiroz, F.

“…Background We recently reported interrelated digestive, cognitive, and hedonic responses to a meal. The aim of this study was to identify brain networks…”
Get full text

Gene expression profiles in peripheral blood mononuclear cells correlate with salience network activity in chronic visceral pain: A pilot study by Gupta, A., Cole, S., Labus, J. S., Joshi, S., Nguyen, T. J., Kilpatrick, L. A., Tillisch, K., Naliboff, B. D., Chang, L., Mayer, E. A.

“…Background Distinct gene expression profiles in peripheral blood mononuclear cells (PBMCs) consistent with increased sympathetic nervous system activity have…”
Get full text

GABA A Receptor Trafficking-Mediated Plasticity of Inhibitory Synapses by Luscher, Bernhard, Fuchs, Thomas, Kilpatrick, Casey L.

“…Proper developmental, neural cell-type-specific, and activity-dependent regulation of GABAergic transmission is essential for virtually all aspects of CNS…”
Get full text

Temporal regulation of nuclear factor one occupancy by calcineurin/NFAT governs a voltage-sensitive developmental switch in late maturing neurons by Ding, Baojin, Wang, Wei, Selvakumar, Tharakeswari, Xi, Hualin Simon, Zhu, Hong, Chow, Chi-Wing, Horton, Jay D, Gronostajski, Richard M, Kilpatrick, Daniel L

“…Dendrite and synapse development are critical for establishing appropriate neuronal circuits, and disrupted timing of these events can alter neural…”
Get full text