Search Results - "Kilpatrick, Katherine E"

Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior by CARLES-KINCH, Kelly, KILPATRICK, Katherine E, STEWART, Jane C, KINCH, Michael S

“…EphA2 is a transmembrane receptor tyrosine kinase that is up-regulated on many aggressive carcinoma cells. Despite its overexpression, the EphA2 on malignant…”
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TNFα-Mediated Inhibition and Reversal of Adipocyte Differentiation Is Accompanied by Suppressed Expression of PPARγ without Effects on Pref-1 Expression by Xing, Hong, Northrop, Jeffrey P., Grove, J. Russell, Kilpatrick, Katherine E., Su, Jui-Lan, Ringold, Gordon M.

“…Abstract Tumor necrosis factor α (TNFα) is a polypeptide hormone with pleiotropic effects on cellular proliferation and differentiation. To investigate how…”
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GRID: A Novel Grb-2-Related Adapter Protein That Interacts with the Activated T Cell Costimulatory Receptor CD28 by Ellis, Jonathan H, Ashman, Claire, Burden, M. Neil, Kilpatrick, Katherine E, Morse, Mary A, Hamblin, Paul A

“…Adapter proteins such as Grb2 play a central role in the formation of signaling complexes through their association with multiple protein binding partners…”
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N-telopeptide of type II collagen interacts with annexin V on human chondrocytes by Lucic, Danijela, Mollenhauer, Juergen, Kilpatrick, Katherine E, Cole, Ada A

“…Type II collagen binds to chondrocytes through integrins and annexin V. While the potential integrin binding sites have been identified, it is unclear which…”
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In vivo expression of a GST-fusion protein mediates the rapid generation of affinity matured monoclonal antibodies using DNA-based immunizations by Kilpatrick, Katherine E, Kerner, Sandy, Dixon, Eric P, Hutchins, Jeff T, Parham, Janet H, Condreay, J Patrick, Pahel, Gregory

“…Previously we demonstrated the rapid generation of affinity matured monoclonal antibody (MAb) producing cell lines following gene gun delivery of DNA using a…”
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Monoclonal antibodies generated against recombinant ATM support kinase activity by Alligood, K J, Milla, M, Rhodes, N, Ellis, B, Kilpatrick, K E, Lee, A, Gilmer, T M, Lansing, T J

“…We report on the rapid generation of two monoclonal antibodies, ATM A16.35 and ATM D16.11, that bind to the kinase domain of mutated ataxia telangiectasia…”
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Characterization of human Gadd45, a p53-regulated protein by Carrier, F, Smith, M L, Bae, I, Kilpatrick, K E, Lansing, T J, Chen, C Y, Engelstein, M, Friend, S H, Henner, W D, Gilmer, T M

“…GADD45 (growth arrest and DNA damage) is a DNA-damage-inducible gene regulated in part by the tumor suppressor p53. A role in negative growth control has…”
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Shorter development of immunoassay for drugs: application of the novel RIMMS technique enables rapid production of monoclonal antibodies to ranitidine by Wring, Stephen A., Kilpatrick, Katherine E., Hutchins, Jeff T., Witherspoon, Samual M., Ellis, Byron, Jenner, William N., Serabjit-Singh, Cosette

“…High affinity, specific murine monoclonal antibodies have been produced for ranitidine using the novel RIMMS (repetitive immunizations, multiple sites)…”
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TNFα-Mediated Inhibition and Reversal of Adipocyte Differentiation Is Accompanied by Suppressed Expression of PPARγ without Effects on Pref-1 Expression1 by Xing, Hong, Northrop, Jeffrey P, Grove, J. Russell, Kilpatrick, Katherine E, Su, Jui-Lan, Ringold, Gordon M

“…Tumor necrosis factor α (TNFα) is a polypeptide hormone with pleiotropic effects on cellular proliferation and differentiation. To investigate how TNFα…”
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Production of a urokinase plasminogen activator-IgG fusion protein (uPA-IgG) in the baculovirus expression system by Kost, Thomas A., Ignar, Diane M., Clay, William C., Andrews, John, Leray, Jeremy D., Overton, Laurie, Hoffman, Christine R., Kilpatrick, Katherine E., Ellis, Byron, Emerson, David L.

“…Numerous studies have demonstrated the importance of urokinase plasminogen activator (uPA) and its receptor, uPAR, in the processes of tumor progression and…”
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Chapter 58 - Rapid Development of Monoclonal Antibodies Using Repetitive Immunizations, Multiple Sites by Dixon, Eric P., Simkins, Stephen, Kilpatrick, Katherine E.

“…This chapter describes procedures for rapid development of monoclonal antibodies using repetitive immunizations, multiple sites (RIMMS). RIMMS capitalizes on…”
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Rapid development of affinity matured monoclonal antibodies using RIMMS by Kilpatrick, K E, Wring, S A, Walker, D H, Macklin, M D, Payne, J A, Su, J L, Champion, B R, Caterson, B, McIntyre, G D

“…Affinity matured murine monoclonal antibody producing cell lines can now be rapidly generated using a novel repetitive, multiple site immunization strategy…”
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Identification of tyrosine phosphorylated adhesion proteins in human cancer cells by Kinch, M S, Kilpatrick, K E, Zhong, C

“…Tyrosine phosphorylation is a form of signal transduction that regulates cell growth, differentiation, migration, and survival. This knowledge has promoted…”
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Gene gun delivered DNA-based immunizations mediate rapid production of murine monoclonal antibodies to the Flt-3 receptor by Kilpatrick, K E, Cutler, T, Whitehorn, E, Drape, R J, Macklin, M D, Witherspoon, S M, Singer, S, Hutchins, J T

“…Class-switched, affinity-matured murine monoclonal antibody (MAb)-producing cell lines were generated against the Flt-3 receptor in less than 4 weeks following…”
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Development of class-switched, affinity-matured monoclonal antibodies following a 7-day immunization schedule by Bynum, J, Andrews, J L, Ellis, B, Kull, Jr, F C, Austin, E A, Kilpatrick, K E

“…Previously we reported making high-affinity monoclonal antibodies (MAbs) 13 days after the onset of Repetitive Immunizations Multiple Sites (RIMMS) strategy…”
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The production and characterization of murine monoclonal antibodies to human Gadd45 raised against a recombinant protein by Kilpatrick, K E, Carrier, F, Smith, M L, Chen, C Y, Lee, A J, Rusnak, D W, Kastan, M B, Fornace, Jr, A J, Champion, B R, Gilmer, T M

“…The production of two different murine monoclonal antibodies to human Gadd45, a protein that is induced in response to DNA damage, is reported. Antibodies were…”
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