Search Results - "Killian, J A"

Sensitivity of Single Membrane-Spanning α-Helical Peptides to Hydrophobic Mismatch with a Lipid Bilayer:  Effects on Backbone Structure, Orientation, and Extent of Membrane Incorporation by de Planque, Maurits R. R, Goormaghtigh, Erik, Greathouse, Denise V, Koeppe, Roger E, Kruijtzer, John A. W, Liskamp, Rob M. J, de Kruijff, Ben, Killian, J. Antoinette

“…The extent of matching of membrane hydrophobic thickness with the hydrophobic length of transmembrane protein segments potentially constitutes a major director…”
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Thermotropic properties of phosphatidylcholine nanodiscs bounded by styrene-maleic acid copolymers by Dominguez Pardo, J.J., Dörr, J.M., Renne, M.F., Ould-Braham, T., Koorengevel, M.C., van Steenbergen, M.J, Killian, J.A.

“…Styrene-maleic acid copolymers (SMA) have been gaining interest in the field of membrane research due to their ability to solubilize membranes into nanodics…”
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Nanodiscs bounded by styrene-maleic acid allow trans-cis isomerization of enclosed photoswitches of azobenzene labeled lipids by Domínguez Pardo, J.J., van Walree, C.A., Egmond, M.R., Koorengevel, M.C., Killian, J.A.

“…Styrene-and-maleic acid (SMA) copolymers behave as amphipathic belts encircling lipids in the form of nanodiscs. It is unclear to what extent the SMA belt…”
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Membrane-Spanning Peptides Induce Phospholipid Flop:  A Model for Phospholipid Translocation across the Inner Membrane of E. coli by Kol, Matthijs A, de Kroon, Anton I. P. M, Rijkers, Dirk T. S, Killian, J. Antoinette, de Kruijff, Ben

“…The mechanism by which phospholipids translocate (flop) across the E. coli inner membrane remains to be elucidated. We tested the hypothesis that the…”
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Polymorphic regulation of membrane phospholipid composition in Escherichia coli by RIETVELD, A. G, KILLIAN, J. A, DOWHAN, W, DE KRUIJFF, B

“…To investigate whether the phase preference of Escherichia coli membrane lipids is regulated by adjustment of the ratio of bilayer to non-bilayer lipids, the…”
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Decellularized Spinach Biomaterials Support Physiologically Relevant Mechanical Cyclic Strain and Prompt a Stretch-Induced Cellular Response by Harris, Ashlee F., Lacombe, Jerome, Sanchez-Ballester, Noelia M., Victor, Shaun, Curran, Killian A. J., Nordquist, Alan R., Thomas, Baiju, Gu, Jian, Veuthey, Jean-Luc, Soulairol, Ian, Zenhausern, Frederic

“…Recently, decellularized plant biomaterials have been explored for their use as tissue engineered substitutes. Herein, we expanded upon the investigation of…”
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Effect of Phospholipids and a Transmembrane Peptide on the Stability of the Cubic Phase of Monoolein: Implication for Protein Crystalization from a Cubic Phase by Chupin, V., Killian, J.A., de Kruijff, B.

“…The cubic phase of monoolein has successfully been used for crystallization of a number of membrane proteins. However, the mechanism of protein crystallization…”
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Regiospecific effect of 1-octanol on cis-trans isomerization of unsaturated fatty acids in the solvent-tolerant strain Pseudomonas putida S12 by HEIPIEPER, H. J, DE WAARD, P, VAN DER MEER, P, KILLIAN, J. A, ISKEN, S, DE BONT, J. A. M, EGGINK, G, DE WOLF, F. A

“…The solvent-tolerant bacterium Pseudomonas putida S12, which adapts its membrane lipids to the presence of toxic solvents by a cis to trans isomerization of…”
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How proteins adapt to a membrane–water interface by Killian, J.Antoinette, von Heijne, Gunnar

“…Membrane proteins present a hydrophobic surface to the surrounding lipid, whereas portions protruding into the aqueous milieu expose a polar surface. But how…”
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Probing membrane protein orientation and structure using fast magic-angle-spinning solid-state NMR by Andronesi, O C, Pfeifer, J R, Al-Momani, L, Ozdirekcan, S, Rijkers, D T S, Angerstein, B, Luca, S, Koert, U, Killian, J A, Baldus, M

“…One and two-dimensional solid-state NMR experiments are discussed that permit probing local structure and overall molecular conformation of membrane-embedded…”
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Hydrophobic mismatch between proteins and lipids in membranes by Killian, J.Antoinette

“…This review addresses the possible consequences of a mismatch in length between the hydrophobic part of membrane-spanning proteins and the hydrophobic bilayer…”
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Thermotropic phase behavior of monoglyceride-dicetylphosphate dispersions and interactions with proteins: a (2)H and (31)P NMR study by Chupin, V, Boots, J W P, Killian, J A, Demel, R A, de Kruijff, B

“…The phase behavior of a 1-[(2)H(35)]-stearoyl-rac-glycerol ([(2)H(35)]-MSG)/dicetylphosphate (DCP) mixture and its interaction with beta-lactoglobulin and…”
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Effect of Nonbilayer Lipids on Membrane Binding and Insertion of the Catalytic Domain of Leader Peptidase by van den Brink-van der Laan, Els, Dalbey, Ross E, Demel, Rudy A, Killian, J. Antoinette, de Kruijff, Ben

“…Biological membranes contain a substantial amount of “nonbilayer lipids”, which have a tendency to form nonlamellar phases. In this study the hypothesis was…”
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Orientations of the tryptophan 9 and 11 side chains of the gramicidin channel based on deuterium nuclear magnetic resonance spectroscopy by Koeppe, R.E., Killian, J.A., Greathouse, D.V.

“…Deuterium nuclear magnetic resonance spectroscopy was used to investigate the orientations of the indole rings of Trp9 and Trp11 in specific indole-d5-labeled…”
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Endogenous mediators in emergency department patients with presumed sepsis: Are levels associated with progression to severe sepsis and death? by Terregino, Carol A., Lopez, Bernard L., Karras, David J., Killian, Anthony J., Arnold, Gerald K.

“…Study Objective: We sought to determine whether levels of the endogenous mediators tumor necrosis factor (TNF)-α, interleukin (IL) 6, and nitric oxide (NO)…”
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Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers by Sparr, Emma, Engel, Maarten F.M., Sakharov, Dmitri V., Sprong, Mariette, Jacobs, Jet, de Kruijff, Ben, Höppener, Jo W.M., Antoinette Killian, J.

“…Fibril formation of islet amyloid polypeptide (IAPP) is associated with cell death of the insulin-producing pancreatic β-cells in patients with Type 2 Diabetes…”
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Self-association of transmembrane alpha-helices in model membranes: importance of helix orientation and role of hydrophobic mismatch by Sparr, Emma, Ash, Walter L, Nazarov, Petr V, Rijkers, Dirk T S, Hemminga, Marcus A, Tieleman, D Peter, Killian, J Antoinette

“…Interactions between transmembrane helices play a key role in almost all cellular processes involving membrane proteins. We have investigated helix-helix…”
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Different Membrane Anchoring Positions of Tryptophan and Lysine in Synthetic Transmembrane α-Helical Peptides by de Planque, Maurits R.R., Kruijtzer, John A.W., Liskamp, Rob M.J., Marsh, Derek, Greathouse, Denise V., Koeppe, Roger E., de Kruijff, Ben, Killian, J. Antoinette

“…Specific interactions of membrane proteins with the membrane interfacial region potentially define protein position with respect to the lipid environment. We…”
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Lipid involvement in protein translocation in Escherichia coli by de Vrije, G J, Batenburg, A M, Killian, J A, de Kruijff, B

“…Signal peptides play an essential role in protein translocation. This review summarizes the current knowledge of the structure of signal peptides and signal…”
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Interaction mode specific reorganization of gel phase monoglyceride bilayers by β-lactoglobulin by Boots, J.-W.P., Chupin, V., Killian, J.A., Demel, R.A., de Kruijff, B.

“…The interaction between β-lactoglobulin and sonicated aqueous dispersions of the gel phase forming monoglyceride monostearoylglycerol were studied using…”
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