Search Results - "Killeen, S"

Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications by Veloso, Artur, Kirkconnell, Killeen S, Magnuson, Brian, Biewen, Benjamin, Paulsen, Michelle T, Wilson, Thomas E, Ljungman, Mats

“…The rate of transcription elongation plays an important role in the timing of expression of full-length transcripts as well as in the regulation of alternative…”
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Urogenital function following robotic and laparoscopic rectal cancer surgery: meta-analysis by Fleming, C A, Cullinane, C, Lynch, N, Killeen, S, Coffey, J C, Peirce, C B

“…Abstract Background Mixed results are reported on clinical and cancer outcomes in laparoscopic rectal cancer surgery (LRCS) compared with robotic rectal cancer…”
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Complete mesocolic resection and extended lymphadenectomy for colon cancer: a systematic review by Killeen, S., Mannion, M., Devaney, A., Winter, D. C.

“…Aim Complete mesocolic excision (CME) and extended lympha‐denectomy (EL) have been proposed as safe procedures for improving colon cancer survival outcomes…”
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Gene length as a biological timer to establish temporal transcriptional regulation by Kirkconnell, Killeen S, Magnuson, Brian, Paulsen, Michelle T, Lu, Brian, Bedi, Karan, Ljungman, Mats

“…Transcriptional timing is inherently influenced by gene length, thus providing a mechanism for temporal regulation of gene expression. While gene size has been…”
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Association between maternal blood lipids during pregnancy and offspring growth trajectories in a predominantly macrosomic cohort: findings from the ROLO longitudinal birth cohort study by Yelverton, C. A., O’Keeffe, L. M., Bartels, H. C., McDonnell, C., Geraghty, A. A., O’Brien, E. C., Killeen, S. L., Twomey, P., Kilbane, M., Crowley, R. K., McKenna, M., McAuliffe, F. M.

“…The purpose of this study is to examine associations between maternal lipid profiles in pregnancy and offspring growth trajectories in a largely macrosomic…”
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Surgical management of complicated and medically refractory inflammatory bowel disease during pregnancy by Killeen, S., Gunn, J., Hartley, J.

“…Aim The medical management of inflammatory bowel disease (IBD) in pregnancy and the puerperium is well defined. Data on surgical management of complicated IBD…”
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Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB-dependent activation of the urokinase plasminogen activator system by Killeen, S D, Wang, J H, Andrews, E J, Redmond, H P

“…Perioperative exposure to lipopolysaccharide (LPS) is associated with accelerated metastatic colorectal tumour growth. LPS directly affects cells through…”
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Provider volume and outcomes for oncological procedures by Killeen, S. D., O'Sullivan, M. J., Coffey, J. C., Kirwan, W. O., Redmond, H. P.

“…Background: Oncological procedures may have better outcomes if performed by high‐volume providers. Methods: A review of the English language literature…”
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Organ Preservation Using Contact Radiotherapy for Early Rectal Cancer: Outcomes of Patients Treated at a Single Centre in the UK by Dhadda, A.S, Martin, A, Killeen, S, Hunter, I.A

“…Abstract Aims Contact radiotherapy for early rectal cancer uses 50 kV X-rays to treat rectal cancers under direct vision. We present data of a series of…”
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Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF- B-dependent activation of the urokinase plasminogen activator system by Killeen, S D, Wang, J H, Andrews, E J, Redmond, H P

“…Perioperative exposure to lipopolysaccharide (LPS) is associated with accelerated metastatic colorectal tumour growth. LPS directly affects cells through…”
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Mapping the colorectal tumor microbiota by Murphy, CL, Barrett, M, Pellanda, P, Killeen, S, McCourt, M, Andrews, E, O’ Riordain, M, Shanahan, F, O’Toole, Pw

“…The gut microbiome in patients with colorectal cancer (CRC) is different than that of healthy controls. Previous studies have profiled the CRC tumor microbiome…”
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Omental pedicle flaps following proctectomy: a systematic review by Killeen, S., Devaney, A., Mannion, M., Martin, S. T., Winter, D. C.

“…Aim Abdominoperineal excision (APR) for cancer carries significant morbidity of the perineal wound. An omental pedicle graft has been used to fill the pelvis…”
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Complete mesocolic excision and central vessel ligation for right colon cancers by Killeen, S., Kessler, H.

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Exploitation of the Toll-like receptor system in cancer: a doubled-edged sword? by KILLEEN, S. D, WANG, J. H, ANDREWS, E. J, REDMOND, H. P

“…The toll-like receptor (TLR) system constitutes a pylogenetically ancient, evolutionary conserved, archetypal pattern recognition system, which underpins…”
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Identifying transcription start sites and active enhancer elements using BruUV-seq by Magnuson, Brian, Veloso, Artur, Kirkconnell, Killeen S., Lima, Leonardo Carmo de Andrade, Paulsen, Michelle T., Ljungman, Emily A., Bedi, Karan, Prasad, Jayendra, Wilson, Thomas E., Ljungman, Mats

“…BruUV-seq utilizes UV light to introduce transcription-blocking DNA lesions randomly in the genome prior to bromouridine-labeling and deep sequencing of…”
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Omentoplasty to assist perineal defect closure following laparoscopic abdominoperineal resection by Killeen, S., Mannion, M., Devaney, A., Winter, D. C.

“…Aim This technical note describes laparoscopic production of a well vascularized, omental flap of adequate size to fill the pelvic floor defect in the course…”
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Capturing the dynamic nascent transcriptome during acute cellular responses: The serum response by Kirkconnell, Killeen S, Paulsen, Michelle T, Magnuson, Brian, Bedi, Karan, Ljungman, Mats

“…Dynamic regulation of gene expression via signal transduction pathways is of fundamental importance during many biological processes such as cell state…”
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A Bacteriophage-Based Platform for Rapid Trace Detection of Proteases by Čapek, Petr, Kirkconnell, Killeen S, Dickerson, Tobin J

“…Sensitive, inexpensive, and rapid protease activity assays are of great merit for clinical diagnostics. Detection of protease-based toxins produced by…”
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Outcomes of Asymptomatic Anastomotic Leaks Found on Routine Postoperative Water-soluble Enema following Anterior Resection for Cancer by Killeen, S., Souroullas, P., Ho Tin, H., Hunter, I. A., O’Grady, H., Gunn, J., Hartley, J. E.

“…Background The incidence and consequence of an anastomotic leak associated with low anterior resection for cancer mandates covering stoma in most cases. A…”
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Clostridium difficile enteritis: A new role for an old foe by Killeen, S, Martin, S.T, Hyland, J, O' Connell, P.R, Winter, D.C

“…Abstract Background Small bowel involvement of Clostridium difficile is increasingly encountered. Data on many management aspects are lacking. Aim To synthesis…”
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