Search Results - "Killeen, Kevin"

A typhoid fever protein capsular matrix vaccine candidate formulated with Advax-CpG adjuvant induces a robust and durable anti-typhoid Vi polysaccharide antibody response in mice, rabbits and nonhuman primates by Honda-Okubo, Yoshikazu, Cartee, Robert T., Thanawastien, Ann, Seung Yang, Jae, Killeen, Kevin P., Petrovsky, Nikolai

“…Typhax is an investigational typhoid fever vaccine candidate that is comprised of Vi polysaccharide from Salmonella enterica serovar typhi (S. Typhi)…”
Get full text

The fundamental aspects and applications of Agilent HPLC-Chip by Yin, Hongfeng, Killeen, Kevin

“…It has been over 3 years since the first publication of the polymer microfluidic HPLC‐Chip technology and more than 1 year since this technology became…”
Get full text

A phase 1 randomized safety, reactogenicity, and immunogenicity study of Typhax: A novel protein capsular matrix vaccine candidate for the prevention of typhoid fever by Cartee, Robert T, Thanawastien, Ann, Griffin Iv, Thomas J, Mekalanos, John J, Bart, Stephan, Killeen, Kevin P

“…Typhoid fever remains a significant cause of morbidity and mortality in developing countries especially in children ≤5 years old. Although the widely available…”
Get full text

Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid by Thanawastien, Ann, Joyce, Kelsey E., Cartee, Robert T., Haines, Laurel A., Pelton, Stephen I., Tweten, Rodney K., Killeen, Kevin P.

“…Pneumolysin is a highly conserved, cholesterol-dependent cytolysin that is an important Streptococcus pneumoniae virulence factor and an attractive target for…”
Get full text

Matrivax profile by Killeen, Kevin P

Get full text

Conjugate-like immunogens produced as protein capsular matrix vaccines by Thanawastien, Ann, Cartee, Robert T., IV, Thomas J. Griffin, Killeen, Kevin P., Mekalanos, John J.

“…Significance Conjugate vaccines have dramatically reduced the incidence of disease in infants and young children caused by encapsulated bacterial pathogens…”
Get full text

A Strategy for Annotating the Human Milk Glycome by Ninonuevo, Milady R, Park, Youmie, Yin, Hongfeng, Zhang, Jinhua, Ward, Robert E, Clowers, Brian H, German, J. Bruce, Freeman, Samara L, Killeen, Kevin, Grimm, Rudolf, Lebrilla, Carlito B

“…Oligosaccharides in human milk represent a group of bioactive molecules that have evolved to be an abundant and diverse component of human milk, even though…”
Get full text

Profile of native N-linked glycan structures from human serum using high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry by Chu, Caroline S, Niñonuevo, Milady R, Clowers, Brian H, Perkins, Patrick D, An, Hyun Joo, Yin, Hongfeng, Killeen, Kevin, Miyamoto, Suzanne, Grimm, Rudolf, Lebrilla, Carlito B

“…Protein glycosylation involves the addition of monosaccharides in a stepwise process requiring no glycan template. Therefore, identifying the numerous…”
Get full text

In vitro characterization and preclinical immunogenicity of Typhax, a typhoid fever protein capsular matrix vaccine candidate by Griffin, Thomas J., Thanawastien, Ann, Cartee, Robert T., Mekalanos, John J., Killeen, Kevin P.

“…Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists…”
Get full text

Hybrid Nanocluster Plasmonic Resonator for Immunological Detection of Hepatitis B Virus by Draz, Mohamed Shehata, Fang, Binbin Amanda, Li, Lanjuan, Chen, Zhi, Wang, Yingjie, Xu, Yuhong, Yang, Jun, Killeen, Kevin, Chen, Fanqing Frank

“…Approximately 88% of the world population lives in regions with intermediate to high incidence of Hepatitis B virus (HBV), yet current serological and…”
Get full text

Microfluidic Gradient Formation for Nanoflow Chip LC by Brennen, Reid A, Yin, Hongfeng, Killeen, Kevin P

“…We report a method for forming a nanoflow liquid chromatography (nano-LC) gradient using a single fluid pump at flow rates below 1 μL/min by passively forming…”
Get full text

Peru-15, a live attenuated oral cholera vaccine, is safe and immunogenic in Bangladeshi toddlers and infants by Qadri, Firdausi, Chowdhury, Mohiul I, Faruque, Shah M, Salam, Mohammed A, Ahmed, Tanvir, Begum, Yasmin A, Saha, Amit, Al Tarique, Abdullah, Seidlein, Lorenz V, Park, Eunsik, Killeen, Kevin P, Mekalanos, John J, Clemens, John D, Sack, David A

“…Abstract A live oral Vibrio cholerae O1 El Tor vaccine, Peru-15 was tested in a double-blind, randomized placebo controlled study for safety and immunogenicity…”
Get full text

Reactogenicity and immunogenicity of live attenuated Salmonella enterica serovar Paratyphi A enteric fever vaccine candidates by Roland, Kenneth L, Tinge, Steven A, Kochi, Sims K, Thomas, Lawrence J, Killeen, Kevin P

“…Abstract Eight Salmonella enterica serovar Paratyphi A strains were screened as candidates to create a live attenuated paratyphoid vaccine. Based on…”
Get full text

Adjuvants and delivery technologies by Killeen, Kevin P

Get full text

Randomized, Controlled Study of the Safety and Immunogenicity of Peru-15, a Live Attenuated Oral Vaccine Candidate for Cholera, in Adult Volunteers in Bangladesh by Qadri, Firdausi, Chowdhury, Mohiul I., Faruque, Shah M., Salam, Mohammed A., Ahmed, Tanvir, Begum, Yasmin A., Saha, Amit, Alam, Mohammed S., Zaman, K., Seidlein, Lorenz V., Park, Eunsik, Killeen, Kevin P., Mekalanos, John J., Clemens, John D., Sack, David A.

“…BackgroundA live oral Vibrio cholerae O1 El Tor vaccine candidate, Peru-15, was studied for safety, immunogenicity, and excretion in phase 1 (inpatient) and…”
Get full text

"The Doctor Quarrels with Some Pictures": Exegesis and Animals in Thomas Browne's Pseudodoxia epidemica by Killeen, Kevin

“…This essay explores Thomas Browne's Pseudodoxia epidemica (1646), with its lengthy book on 'errors' in animal lore. In the limited critical literature on…”
Get full text

Construction and preclinical evaluation of recombinant Peru-15 expressing high levels of the cholera toxin B subunit as a vaccine against enterotoxigenic Escherichia coli by Roland, Kenneth L, Cloninger, Cheryl, Kochi, Sims K, Thomas, Lawrence J, Tinge, Steven A, Rouskey, Craig, Killeen, Kevin P

“…Abstract Enterotoxigenic Escherichia coli (ETEC) is the leading cause of traveler's diarrhea. The heat-labile (LT) and heat-stable (ST) toxins mediate ETEC…”
Get full text

Randomized, Controlled Human Challenge Study of the Safety, Immunogenicity, and Protective Efficacy of a Single Dose of Peru-15, a Live Attenuated Oral Cholera Vaccine by COHEN, Mitchell B, GIANNELLA, Ralph A, KILLEEN, Kevin P, BEAN, Judy, TAYLOR, David N, PARKER, Susan, HOEPER, Amy, WOWK, Stephen, HAWKINS, Jennifer, KOCHI, Sims K, SCHIFF, Gilbert

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

MassCode liquid arrays as a tool for multiplexed high-throughput genetic profiling by Richmond, Gregory S, Khine, Htet, Zhou, Tina T, Ryan, Daniel E, Brand, Tony, McBride, Mary T, Killeen, Kevin

“…Multiplexed detection assays that analyze a modest number of nucleic acid targets over large sample sets are emerging as the preferred testing approach in such…”
Get full text

Live, attenuated Salmonella typhimurium vectoring Campylobacter antigens by Sizemore, Donata R., Warner, Beth, Lawrence, Julie, Jones, Amy, Killeen, Kevin P.

“…We describe the evaluation of three live, attenuated Δ phoP/ Q Salmonella enteric serovar Typhimurium strains expressing PEB1 minus its signal sequence…”
Get full text