Search Results - "Kilinc, Yasemin"
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Meningeal mast cell‐mediated mechanisms of cholinergic system modulation in neurogenic inflammation underlying the pathophysiology of migraine
Published in The European journal of neuroscience (01-05-2024)“…Growing evidence indicates that the parasympathetic system is implicated in migraine headache. However, the cholinergic mechanisms in the pathophysiology of…”
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D2 dopamine receptor‐mediated mechanisms of dopaminergic system modulation in in vivo and in vitro experimental models of migraine
Published in The European journal of neuroscience (01-03-2024)“…The dopaminergic system is implicated in the pathophysiology of migraine. However, the underlying mechanisms remain unclear. We explored the effects and…”
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Esculetin alleviates pentylenetetrazole-induced seizures, cognitive impairment and pro-inflammatory cytokines and suppresses penicillin-induced epileptiform activity in rats
Published in Life sciences (1973) (15-01-2023)“…To investigate the effects of different doses of esculetin on epileptiform activity, behavioral seizures, memory impairment, and cortical and hippocampal…”
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The prevalence of vitamin D deficiency and the factors affecting vitamin D levels in children admitted to the outpatient clinic of pediatric endocrinology in Bolu Province
Published in Archives de pédiatrie : organe officiel de la Société française de pédiatrie (01-11-2023)“…BACKGROUNDThe present study aimed to determine the rate of vitamin D deficiency in children who presented to the pediatric endocrinology outpatient clinic in…”
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Capsaicin attenuates excitotoxic-induced neonatal brain injury and brain mast cell-mediated neuroinflammation in newborn rats
Published in Chemico-biological interactions (01-05-2023)“…Excitotoxicity and neuroinflammation are key contributors to perinatal brain injuries. Capsaicin, an active ingredient of chili peppers, is a potent exogenous…”
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Piperine Nanoparticles for Topical Application: Preparation, Characterization, In vitro and In silico Evaluation
Published in ChemistrySelect (Weinheim) (25-10-2019)“…In this study, piperine was investigated as a drug molecule due to its analgesic and anti‐inflammatory properties. Piperine was encapsulated with…”
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Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats
Published in Arquivos de neuro-psiquiatria (01-01-2022)“…Epilepsy has neuropsychiatric comorbidities such as depression, bipolar disorder, and anxiety. Drugs that target epilepsy may also be useful for its…”
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Molecular docking studies of YKT tripeptide and drug delivery system with poly(ε‐caprolactone) nanoparticles
Published in Archiv der Pharmazie (Weinheim) (01-05-2022)“…Tyrosyllysylthreonine (YKT) is a peptide structure that contains three different amino acids in its structure and has anticancer properties. The main purpose…”
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New nanodrug design for cancer therapy: Its synthesis, formulation, in vitro and in silico evaluations
Published in Archiv der Pharmazie (Weinheim) (01-11-2020)“…The aim of this study was to develop a novel nanosize drug candidate for cancer therapy. For this purpose, (S)‐methyl…”
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Novel Fitc-Labeled Igy Antibody: Fluorescence Imaging Toxoplasma Gondii In Vitro
Published in Scientific reports (12-04-2017)“…Toxoplasmosis is caused by T . gondii and can create serious health problems in humans and also worldwide economic harm. Because of the clinical and veterinary…”
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Gender role attitudes and well-being of German and refugee adolescents—same or different?
Published in BMC psychiatry (08-09-2023)“…Abstract Background Assumed differences in gender role attitudes (GRAs) of German adolescents and refugee adolescents from the Middle East are often discussed,…”
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Structural, spectroscopic, in silico, in vitro and DNA binding evaluations of tyrosyl-lysyl-threonine
Published in Journal of biomolecular structure & dynamics (01-01-2022)“…The main objective of the present study is to investigate the molecular structure and DNA binding interaction of the tyrosyl-lysyl-threonine (YKT) tripeptide,…”
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Structural Characterization and Drug Delivery System of Natural Growth-Modulating Peptide Against Glioblastoma Cancer
Published in International journal of peptide research and therapeutics (01-09-2021)“…The aim of the current study was to design a drug delivery nano-system of natural growth-modulating peptide known as GHK that naturally occurs in human plasma,…”
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Laurus nobilis L. Essential Oil-Loaded PLGA as a Nanoformulation Candidate for Cancer Treatment
Published in Molecules (Basel, Switzerland) (15-03-2022)“…The aim of this study was to obtain essential oil (LNEO) from the L. plant, and to prepare LNEO-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs)…”
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New coumarin derivative with potential antioxidant activity: Synthesis, DNA binding and in silico studies (Docking, MD, ADMET)
Published in Arabian journal of chemistry (01-02-2023)“…[Display omitted] A new coumarin derivative, 7-((8-(4-benzylpiperidin-1-yl)octyl)oxy)-4-methyl-2H-chromen-2-one (C3), was synthesized by two-step alkylation…”
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Development of nanoformulation for hyperpigmentation disorders: Experimental evaluations, in vitro efficacy and in silico molecular docking studies
Published in Arabian journal of chemistry (01-12-2022)“…Hyperpigmentation is a crucial dermatological disorder. This study aims to formulate a nanoemulsion formulation containing chlorogenic acid (CA) for…”
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Fabrication and Characterization of Saffron Stamen Aqueous Extract Controlled Release System as Potential Topical Treatment of Thermal Burn Wounds
Published in ChemistrySelect (Weinheim) (07-07-2021)“…In our study, we aimed the preparation of Saffron stamen aqueous extract (SSAE) loaded chitosan nanoparticles (CNPs) to be used topically for thermal burns…”
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Preparation and cytotoxicity of Coriandrum sativum L. oil-loaded chitosan nanoparticles
Published in Journal of the Turkish Chemical Society, Section A, Chemistry (2018)“…Coriandrum sativum L. (coriander) oil has antibacterial, antifungal, and antimicrobial activity. This study prepared and characterized chitosan nanoparticles…”
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Development and characterization of a formulation based covalent conjugation with polyacrylic acid and recombinant major surface antigen (SAG1) of Toxoplasma gondii
Published in Turkish Journal of Biochemistry (01-12-2017)“…Abstract Introduction Toxoplasmosis is a major disease caused by Toxoplasma gondii that infects approximately half the world’s population. The development of…”
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In vitro and in silico evaluation of the design of nano-phyto-drug candidate for oral use against Staphylococcus aureus
Published in PeerJ (San Francisco, CA) (08-06-2023)“…is a medicinal plant with many important properties, such as antibacterial, anticancer, and anti-hypotensive properties. Although various studies reported the…”
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