Search Results - "Kilic, Fusun"

Post-translational modifications of serotonin transporter by Cooper, Anthonya, Woulfe, Donna, Kilic, Fusun

“…The serotonin transporter (SERT) is an oligomeric glycoprotein with two sialic acid residues on each of two complex oligosaccharide molecules. Studies using in…”
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The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis by Joo, Joung Hyuck, Wang, Bo, Frankel, Elisa, Ge, Liang, Xu, Lu, Iyengar, Rekha, Li-Harms, XiuJie, Wright, Christopher, Shaw, Timothy I., Lindsten, Tullia, Green, Douglas R., Peng, Junmin, Hendershot, Linda M., Kilic, Fusun, Sze, Ji Ying, Audhya, Anjon, Kundu, Mondira

“…ULK1 and ULK2 are thought to be essential for initiating autophagy, and Ulk1/2-deficient mice die perinatally of autophagy-related defects. Therefore, we used…”
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Serotonin transporter protects the placental cells against apoptosis in caspase 3‐independent pathway by Hadden, Coedy, Fahmi, Tariq, Cooper, Anthonya, Savenka, Alena V., Lupashin, Vladimir V., Roberts, Drucilla J., Maroteaux, Luc, Hauguel‐de Mouzon, Sylvie, Kilic, Fusun

“…Serotonin (5‐HT) and its specific transporter, SERT play important roles in pregnancy. Using placentas dissected from 18d gestational SERT‐knock out (KO),…”
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Responses of Plasma Catecholamine, Serotonin, and the Platelet Serotonin Transporter to Cigarette Smoking by Lowery, 3rd, Curtis Lee, Woulfe, Donna, Kilic, Fusun

“…Cigarette smoking is one of the major causes of coronary heart disease with a thirty percent mortality rate in the United States. Cigarette smoking acting on…”
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Retraction Note: Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability by Li, Yicong, Hadden, Coedy, Cooper, Anthonya, Ahmed, Asli, Wu, Hong, Lupashin, Vladimir V., Mayeux, Philip R., Kilic, Fusun

“…This article has been retracted…”
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GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake by Li, Yicong, Hadden, Coedy, Singh, Preeti, Mercado, Charles P, Murphy, Pamela, Dajani, Nafisa K, Lowery, Curtis L, Roberts, Drucilla J, Maroteaux, Luc, Kilic, Fusun

“…Serotonin (5-HT) transporter (SERT) regulates the level of 5-HT in placenta. Initially, we found that in gestational diabetes mellitus (GDM), whereas free…”
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The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis by Joo, Joung Hyuck, Wang, Bo, Frankel, Elisa, Ge, Liang, Xu, Lu, Iyengar, Rekha, Li-Harms, XiuJie, Wright, Christopher, Shaw, Timothy I., Lindsten, Tullia, Green, Douglas R., Peng, Junmin, Hendershot, Linda M., Kilic, Fusun, Sze, Ji Ying, Audhya, Anjon, Kundu, Mondira

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A serotonin-induced N-glycan switch regulates platelet aggregation by Mercado, Charles P., Quintero, Maritza V., Li, Yicong, Singh, Preeti, Byrd, Alicia K., Talabnin, Krajang, Ishihara, Mayumi, Azadi, Parastoo, Rusch, Nancy J., Kuberan, Balagurunathan, Maroteaux, Luc, Kilic, Fusun

“…Serotonin (5-HT) is a multifunctional signaling molecule that plays different roles in a concentration-dependent manner. We demonstrated that elevated levels…”
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Cigarette Smoking-Associated Alterations in Serotonin/Adrenalin Signaling Pathways of Platelets by Lowery, 3rd, Curtis Lee, Elliott, Clay, Cooper, Anthonya, Hadden, Coedy, Sonon, Roberto N, Azadi, Parastoo, Williams, D Keith, Marsh, James D, Woulfe, Donna S, Kilic, Fusun

“…Cigarette smoking plays a major role in cardiovascular diseases. The acute effects of cigarette smoking produce central nervous system-mediated activation of…”
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Oligomerization of Serotonin Transporter and Its Functional Consequences by Kilic, Fusun, Rudnick, Gary

“…Two forms of serotonin transporter (SERT) were prepared with different epitope tags. When co-expressed in HeLa cells, the form containing a FLAG tag (Res-FLAG)…”
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Down-regulation of the serotonin transporter in hyperreactive platelets counteracts the pro-thrombotic effect of serotonin by Ziu, Endrit, Mercado, Charles P, Li, Yicong, Singh, Preeti, Ahmed, Billow A, Freyaldenhoven, Samuel, Lensing, Shelly, Ware, Jerry, Kilic, Fusun

“…Abstract An elevated plasma concentration of serotonin ([5-HT]) is a common feature of cardiovascular disease often associated with enhanced platelet…”
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The Coordinated Changes in Platelet Glycan Patterns with Blood Serotonin and Exosomes by Kilic, Fusun

“…The structures of glycans, specifically their terminal positions, play an important role as ligands for receptors in regulating the adhesion ability of…”
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A human serotonin transporter mutation causes constitutive activation of transport activity by Kilic, Fusun, Murphy, Dennis L, Rudnick, Gary

“…A rarely occurring variant of human serotonin transporter (hSERT) was tested for its functional consequences in HeLa and COS-7 cells. The variant, in which…”
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The nature of the binding between insulin receptor and serotonin transporter in placenta (review) by Kilic, Fusun

“…The interplay between the insulin receptor (IR) and serotonin transporter (SERT) allows reciprocal regulation of each other's physiological roles to ensure…”
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Effect of serotonin on platelet function in cocaine exposed blood by Ziu, Endrit, Hadden, Coedy, Li, Yicong, Lowery, Curtis Lee, Singh, Preeti, Ucer, Serra S., Mercado, Charles P., Gu, Howard H., Kilic, Fusun

“…5-hydroxytryptamine (5-HT) reuptake inhibitors counteract the pro-thrombotic effect of elevated plasma 5-HT by down-regulating the 5-HT uptake rates of…”
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The Role of ERp44 in Maturation of Serotonin Transporter Protein by Freyaldenhoven, Samuel, Li, Yicong, Kocabas, Arif M., Ziu, Enrit, Ucer, Serra, Ramanagoudr-Bhojappa, Raman, Miller, Grover P., Kilic, Fusun

“…In heterologous and endogenous expression systems, we studied the role of ERp44 and its complex partner endoplasmic reticulum (ER) oxidase 1-α (Ero1-Lα) in…”
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Impact of elevated plasma serotonin on global gene expression of murine megakaryocytes by Mercado, Charles P, Byrum, Stephanie, Beggs, Marjorie L, Ziu, Endrit, Singh, Preeti, Raj, Vinay R, Haun, Randy S, Kilic, Fusun

“…Serotonin (5-HT) is a biogenic amine that also acts as a mitogen and a developmental signal early in rodent embryogenesis. Genetic and pharmacological…”
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Serotonin Transamidates Rab4 and Facilitates Its Binding to the C Terminus of Serotonin Transporter by Ahmed, Billow A., Jeffus, Brandon C., Bukhari, Syed I.A., Harney, Justin T., Unal, Resat, Lupashin, Vladimir V., van der Sluijs, Peter, Kilic, Fusun

“…The serotonin transporter (SERT) on the plasma membrane is the major mechanism for the clearance of plasma serotonin (5-hydroxytryptamine (5HT)). The uptake…”
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The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network by Ahmed, Billow A, Bukhari, Irfan A, Jeffus, Brandon C, Harney, Justin T, Thyparambil, Sheeno, Ziu, Endrit, Fraer, Mony, Rusch, Nancy J, Zimniak, Piotr, Lupashin, Vladimir, Tang, Dale, Kilic, Fusun

“…The C-terminus of the serotonin transporter (SERT) contains binding domains for different proteins and is critical for its functional expression. In endogenous…”
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Serotonin: a different player in hypertension-associated thrombosis by Fraer, Mony, Kilic, Fusun

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