Search Results - "Kildsgaard, J."

Sublingual immunotherapy reduces allergic symptoms in a mouse model of rhinitis by Brimnes, J., Kildsgaard, J., Jacobi, H., Lund, K.

“…Summary Background Sublingual immunotherapy (SLIT) is a clinically effective treatment in both pollen and house dust mite‐induced rhinitis and asthma. However,…”
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Cutting Edge: Targeted Disruption of the C3a Receptor Gene Demonstrates a Novel Protective Anti-Inflammatory Role for C3a in Endotoxin-Shock by Kildsgaard, Jens, Hollmann, Travis J, Matthews, Kirstin W, Bian, Ka, Murad, Ferid, Wetsel, Rick A

“…The complement anaphylatoxin C3a, on binding the C3aR, mediates numerous proinflammatory activities. In addition, recent in vitro studies with C3a have…”
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Expression of the Complement Anaphylatoxin C3a and C5a Receptors on Bronchial Epithelial and Smooth Muscle Cells in Models of Sepsis and Asthma by Drouin, Scott M, Kildsgaard, Jens, Haviland, Joie, Zabner, Joseph, Jia, Hong Pen, McCray, Paul B., Jr, Tack, Brian F, Wetsel, Rick A

“…The presence of the complement-derived anaphylatoxin peptides, C3a and C5a, in the lung can induce respiratory distress characterized by contraction of the…”
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Cutting Edge: The Absence of C3 Demonstrates a Role for Complement in Th2 Effector Functions in a Murine Model of Pulmonary Allergy by Drouin, Scott M, Corry, David B, Kildsgaard, Jens, Wetsel, Rick A

“…Asthma is a chronic disease of the lung resulting from airway obstruction. Although the initiating causes are not entirely clear, the airway inflammation in…”
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Sublingual Immunotherapy Induce Systemic T-cell Tolerance in Naive Mice by Brimnes, J, Kildsgaard, J, Jacobi, H, Lund, K

“…When the SLIT treated mice were subsequently challenged intraperitoneally with alum adsorbed Phl p extract it could be demonstrated that SLIT leads to the…”
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A Novel Mouse Model of Whole Pollen Grain Induced Rhinitis by Brimnes, J, Kildsgaard, J, Jacobi, H, Lund, K

“…Mice sensitized for 3 weeks, rested for 2 weeks and challenged for 3 weeks displayed clear signs of rhinitis such as increased serum IgE, increased sneezing,…”
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Kinetics of cytokine production in human T-cell cultures by Millner, A.H., Kildsgaard, J., Würtzen, P.A.

“…In in vitro culture systems cytokines are used as hallmarks of T-cell responses and to distinguish between Th1, Th2, and Treg responses…”
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Sublingual immunotherapy (SLIT) in sensitised mice induces mucosal IgA antibodies by Kildsgaard, J., Brimnes, J., Jacobi, H.H., Lund, K.

“…Furthermore, secretory IgA from BAL or NAL was able to block the binding of serum IgE to a biotinylated extract of Phl p. In contrast to IgA, no changes in…”
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Immunochemical determination of the cellular content of polypeptide chain release factor RF3 in Escherichia coli by Holst-Hansen, P., Kildsgaard, J., MacDougall, J., Palacios Moreno, J.M., Egebjerg, J., Mortensen, K.K., Sperling-Petersen, H.U.

“…Polypeptide chain termination in Escherchia coli is known to require two codon specific release factors. RF1 and RF2. A third factor, RF3, has been described…”
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Absence of the Complement Anaphylatoxin C3a Receptor Suppresses Th2 Effector Functions in a Murine Model of Pulmonary Allergy by Drouin, Scott M, Corry, David B, Hollman, Travis J, Kildsgaard, Jens, Wetsel, Rick A

“…Asthma is a chronic inflammatory disease of the lung resulting in airway obstruction. The airway inflammation of asthma is strongly linked to Th2 lymphocytes…”
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Numerical analysis of biological clogging in two-dimensional sand box experiments by Kildsgaard, Jesper, Engesgaard, Peter

“…Two-dimensional models for biological clogging and sorptive tracer transport were used to study the progress of clogging in a sand box experiment. The sand box…”
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Sublingual Immunotherapy Reduce Allergic Symptoms in a Mouse Model of Rhinitis by Brimnes, J., KIldsgaard, J., Jacobi, H., Lund, K.

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Tracer Tests and Image Analysis of Biological Clogging in a Two-Dimensional Sandbox Experiment by Kildsgaard, Jesper, Engesgaard, Peter

“…A two‐dimensional flow experiment on biological clogging was carried out by biostimulating a sandbox packed with sand inoculated with bacteria. Biostimulation…”
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Genetic Deficiency of Acylation Stimulating Protein (ASP(C3ades-Arg)) Does Not Cause Hyperapobetalipoproteinemia in Mice by Wetsel, R A, Kildsgaard, J, Zsigmond, E, Liao, W, Chan, L

“…The acylation stimulating protein (ASP) is a 76-amino acid peptide that has been proposed as a potent mediator of triglyceride synthesis and, when functionally…”
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The Absence of C3 Demonstrates a Role for Complement in Th2 Effector Functions in a Murine Model of Pulmonary Allergy by Drouin, S M, Corry, D B, Kildsgaard, J, Wetsel, R A

“…Asthma is a chronic disease of the lung resulting from airway obstruction. Although the initiating causes are not entirely clear, the airway inflammation in…”
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Binding of Escherichia coli initiation factor IF2 to 30S ribosomal subunits: a functional role for the N-terminus of the factor by Moreno, J M, Kildsgaard, J, Siwanowicz, I, Mortensen, K K, Sperling-Petersen, H U

“…In the initiation step of bacterial protein synthesis initiation factor IF2 has to join the 30S ribosomal subunit in order to promote the binding of the…”
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Targeted Disruption of the C3a Receptor Gene Demonstrates a Novel Protective Anti-Inflammatory Role for C3a in Endotoxin-Shock by Kildsgaard, J, Hollmann, T J, Matthews, K W, Bian, K, Murad, F, Wetsel, R A

“…The complement anaphylatoxin C3a, on binding the C3aR, mediates numerous proinflammatory activities. In addition, recent in vitro studies with C3a have…”
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A critical evaluation of the putative role of C3adesArg (ASP) in lipid metabolism and hyperapobetalipoproteinemia by Kildsgaard, Jens, Zsigmond, Eva, Chan, Lawrence, Wetsel, Rick A

“…The acylation stimulating protein, ASP is a small, basic serum protein capable of stimulating triglyceride synthesis in cultured fibroblasts and adipocytes…”
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Cloning, expression, sequence determination, and chromosome localization of the mouse complement C3a anaphylatoxin receptor gene by Hollma, Travis J., Haviland, David L., Kildsgaard, Jens, Watts, Kirstin, Wetsela, Rick A.

“…The complement C3a anaphylatoxin receptor (C3aR) is a seven-transmembrane G-protein coupled chemoattractant receptor that on binding the C3a peptide ligand…”
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A six‐domain structural model for Escherichia coli translation initiation factor IF2. Characterisation of twelve surface epitopes by Mortensen, Kim Kusk, Kildsgaard, Jens, Moreno, Juan Manuel Palacios, de, Søren A., Steffensen, A., Egebjerg, Janni, Sperling‐Petersen, Hans Uffe

“…The Escherichia coli translation initiation factor IF2 is a 97 kDa protein which interacts with the initiator fMet‐tRNAf/Met, GTP and the ribosomal subunits…”
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