Search Results - "Kilby, M.D"

The immunological basis of villitis of unknown etiology – Review by Tamblyn, J.A, Lissauer, D.M, Powell, R, Cox, P, Kilby, M.D

“…Abstract Villitis of unknown etiology (VUE) represents a common placental inflammatory lesion, primarily, but not exclusively, identifiable T lymphocytes at…”
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Vitamin D promotes human extravillous trophoblast invasion in vitro by Chan, S.Y, Susarla, R, Canovas, D, Vasilopoulou, E, Ohizua, O, McCabe, C.J, Hewison, M, Kilby, M.D

“…Abstract Introduction Incomplete human extravillous trophoblast (EVT) invasion of the decidua and maternal spiral arteries is characteristic of pre-eclampsia,…”
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Dysregulation of maternal and placental vitamin D metabolism in preeclampsia by Tamblyn, J.A, Susarla, R, Jenkinson, C, Jeffery, L.E, Ohizua, O, Chun, R.F, Chan, S.Y, Kilby, M.D, Hewison, M

“…Abstract Introduction Epidemiology has linked preeclampsia (PET) to decreased maternal serum 25-hydroxyvitamin D3 (25(OH)D3). However, alterations in systemic…”
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Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner by Vasilopoulou, E., Loubière, L.S., Lash, G.E., Ohizua, O., McCabe, C.J., Franklyn, J.A., Kilby, M.D., Chan, S.Y.

“…STUDY QUESTION Does triiodothyronine (T3) regulate the secretion of angiogenic growth factors and cytokines by human decidual cells isolated from early…”
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Long-term renal and neurodevelopmental outcome in infants with LUTO, with and without fetal intervention by Morris, R. Katie, Kilby, M.D

“…Abstract Congenital lower urinary tract obstruction (LUTO) is a heterogeneous group of pathologies, the most common being posterior urethral valves (PUV) or…”
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Change in diagnostic confidence brought about by using in utero MRI for fetal structural brain pathology: analysis of the MERIDIAN cohort by Griffiths, P.D, Bradburn, M, Campbell, M.J, Connolly, D.J.A, Cooper, C.L, Jarvis, D, Kilby, M.D, Mason, G, Mooney, C, Robson, S.C, Wailoo, A

“…Aim To measure possible change in diagnostic confidence by performing in utero magnetic resonance imaging (iuMRI) studies on fetuses with brain abnormalities…”
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Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction by Loubière, L.S, Vasilopoulou, E, Bulmer, J.N, Taylor, P.M, Stieger, B, Verrey, F, McCabe, C.J, Franklyn, J.A, Kilby, M.D, Chan, S.-Y

“…Abstract Thyroid hormones (TH) are important for the development of the human fetus and placenta from very early gestation. The transplacental passage of TH…”
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Single twin demise: consequence for survivors by Hillman, S.C, Morris, R.K, Kilby, M.D

“…Summary Multiple pregnancies, the majority of which are twins, are at substantially higher risk of fetal morbidity and mortality when compared with singleton…”
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Maternal cellular immunity to fetal HY antigens during pregnancy by Lissauer, D, Piper, K, Goodyear, O, Moss, P.A.H, Kilby, M.D

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Nonimmune Hydrops Fetalis — More Than Meets the Eye? by Kilby, M.D.

“…(N Engl J Med. 2020;383:1785–1786) Nonimmune Hydrops Fetalis (NIHF) is typically defined as fetal fluid accumulation in two sites and affects up to 1 in 1,700…”
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Separase, securin and Rad21 in neural cell growth by Pemberton, H.N., Franklyn, J.A., Boelaert, K., Chan, S.Y., Kim, D.S., Kim, C., Cheng, S.Y., Kilby, M.D., McCabe, C.J.

“…The key mitotic regulator securin is expressed at low levels in fetal brain compared with adult, and modulates the proliferation of human embryonic neuronal…”
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Maternal serum markers of placental damage in uncomplicated dichorionic and monochorionic pregnancies in comparison with monochorionic pregnancies complicated by severe twin-to-twin transfusion syndrome and the response to fetoscopic laser ablation by Fox, C.E, Pretlove, S.J, Chan, B.C, Mahony, R.T, Holder, R, Kilby, M.D

“…Abstract Objective Twin-to-twin transfusion syndrome (TTTS) is a morbid perinatal condition associated with abnormal placentation and is treated by fetoscopic…”
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Association Between Thyroid Autoantibodies and Miscarriage and Preterm Birth: Meta-analysis of Evidence by Thangaratinam, S, Tan, A, Knox, E, Kilby, M.D, Franklyn, J, Coomarasamy, A

“…(BMJ. 2011;342:d2616)…”
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Maternal effector T cells within decidua: The adaptive immune response to pregnancy? by Lissauer, D., Kilby, M.D., Moss, P.

“…In human pregnancy the maternal immune system plays a critical role in the regulation of many aspects of human reproduction including implantation,…”
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EP01.04: Improving early gene detection using a new bioinformatics tool specific to prenatal phenotyping: a case study on CHARGE syndrome by Chantry‐Darmon, C., Besson, R., Spaggiari, E., Choy, R., Stirnemann, J., Kilby, M.D., Ville, Y.

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Fetal hydrops and the Incremental yield of Next‐generation sequencing over standard prenatal Diagnostic testing (FIND) study: prospective cohort study and meta‐analysis by Mone, F., Eberhardt, R. Y., Hurles, M. E., Mcmullan, D. J., Maher, E. R., Lord, J., Chitty, L. S., Dempsey, E., Homfray, T., Giordano, J. L., Wapner, R. J., Sun, L., Sparks, T. N., Norton, M. E., Kilby, M. D.

“…ABSTRACT Objective To determine the incremental yield of exome sequencing (ES) over chromosomal microarray analysis (CMA) or karyotyping in prenatally…”
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OC03.01: Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcomes set by Mustafa, H., Khalil, A., Johnson, S., Gordijn, S., Ganzevoort, W., Melling, C., Koh, C., Mandy, G., Kilby, M.D., Johnson, A., Quintero, R., Shamshirsaz, A., Nassr, A.

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VP33.06: Non‐immune hydrops fetalis and diagnostic yield with prenatal‐exome sequencing: a case series by Mone, F., Doyle, S., Hamilton, S., Allen, S., Williams, D., Kilby, M.D.

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VP28.02: Evolving phenotypes and the clinical impact of progressive prenatal‐exome sequencing pathways: a cohort study by Mone, F., Doyle, S., Abu‐Subieh, H., Hamilton, S., Marton, T., Williams, D., Allen, S., Kilby, M.D.

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VP33.04: Perinatal and genetic outcomes in anomalous fetuses of consanguineous union: a cohort study by Mone, F., Doyle, S., Hamilton, S., Allen, S., Marton, T., Williams, D., Kilby, M.D.

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