Search Results - "Kilav, R"
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Parathyroid hormone gene expression in hypophosphatemic rats
Published in The Journal of clinical investigation (01-07-1995)“…Phosphate is central to bone metabolism and we have therefore studied whether parathyroid hormone (PTH) is regulated by dietary phosphate in vivo. Weanling…”
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2
Molecular mechanisms of secondary hyperparathyroidism
Published in Pediatric nephrology (Berlin, West) (01-07-2000)“…Secondary hyperparathyroidism is a frequent complication of chronic renal failure (CRF) and a major factor in the pathogenesis of renal osteodystrophy. A high…”
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3
New insights into the regulation of parathyroid hormone synthesis and secretion in chronic renal failure
Published in Nephrology, dialysis, transplantation (1996)“…The main factors which regulate parathyroid hormone (PTH) production are calcium, phosphate, vitamin D and the sex steroids, estrogens and progestagins…”
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4
Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet
Published in Nephrology, dialysis, transplantation (01-08-1997)“…The murine analogue of X-linked hypophosphataemia is the Hyp mouse; it has chronic phosphate depletion from an inherited defect of renal tubular reabsorption…”
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Mechanisms of secondary hyperparathyroidism
Published in American journal of physiology. Renal physiology (01-09-2002)“…Small decreases in serum Ca(2+) and more prolonged increases in serum phosphate (P(i)) stimulate the parathyroid (PT) to secrete parathyroid hormone (PTH), and…”
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6
New aspects in the control of parathyroid hormone secretion
Published in Current opinion in nephrology and hypertension (01-07-1994)“…Ca2+ binds to a parathyroid cell Ca2+ receptor, which is G protein-coupled and activates inositol triphosphate production. Mutations in the Ca(2+)-sensing…”
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7
RNA-Protein Binding and Post-transcriptional Regulation of Parathyroid Hormone Gene Expression by Calcium and Phosphate
Published in The Journal of biological chemistry (27-02-1998)“…Parathyroid hormone (PTH) regulates serum calcium and phosphate levels, which, in turn, regulate PTH secretion and mRNA levels. PTH mRNA levels are markedly…”
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8
A Conserved cis-Acting Element in the Parathyroid Hormone 3′-Untranslated Region Is Sufficient for Regulation of RNA Stability by Calcium and Phosphate
Published in The Journal of biological chemistry (23-03-2001)“…Calcium and phosphate regulate parathyroid hormone (PTH) gene expression post-transcriptionally by changes in protein-PTH mRNA 3′-untranslated region (UTR)…”
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The Protein Phosphatase Calcineurin Determines Basal Parathyroid Hormone Gene Expression
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2005)“…Calcium and phosphate regulate PTH mRNA stability through differences in binding of parathyroid (PT) proteins to a minimal 63-nucleotide (nt) cis-acting…”
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10
Regulation of the parathyroid hormone gene by vitamin D, calcium and phosphate
Published in Kidney international (01-12-1999)“…Regulation of the parathyroid hormone gene by vitamin D, calcium, and phosphate. Secondary hyperparathyroidism is a frequent complication of chronic renal…”
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Cis and trans acting factors in the regulation of parathyroid hormone (PTH) mRNA stability by calcium and phosphate
Published in FEBS Letters (02-10-2002)“…Calcium and phosphate regulate parathyroid hormone (PTH) mRNA stability through differences in binding of parathyroid proteins to an element in its…”
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The Parathyroid Hormone mRNA 3′-Untranslated Region AU-rich Element Is an Unstructured Functional Element
Published in The Journal of biological chemistry (16-01-2004)“…Parathyroid hormone (PTH) gene expression is regulated post-transcriptionally by hypocalcemia and hypophosphatemia. This regulation is dependent upon binding…”
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Dynein light chain binding to a 3'-untranslated sequence mediates parathyroid hormone mRNA association with microtubules
Published in The Journal of clinical investigation (01-02-2000)“…The 3'-untranslated region (UTR) of mRNAs binds proteins that determine mRNA stability and localization. The 3'-UTR of parathyroid hormone (PTH) mRNA…”
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14
Regulation of the parathyroid hormone gene by calcium, phosphate and 1,25-dihydroxyvitamin D
Published in Nephrology, dialysis, transplantation (01-01-1998)Get full text
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15
Coordinate regulation of rat renal parathyroid hormone receptor mRNA and Na-Pi cotransporter mRNA and protein
Published in The American journal of physiology (01-06-1995)“…Parathyroid hormone (PTH) acts on the kidney by binding to the PTH receptor, leading to a decrease in the active renal reabsorption of phosphate by the Na-Pi…”
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16
The kidney sodium-calcium exchanger
Published in Annals of the New York Academy of Sciences (01-04-1996)Get more information
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17
Calcium, phosphate, vitamin D, and the parathyroid
Published in Pediatric nephrology (Berlin, West) (01-06-1996)“…The main factors which regulate parathyroid hormone (PTH) production are calcium, phosphate, vitamin D, and estrogens. Hypocalcemia leads to increased PTH…”
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18
New insights into the regulation of parathyroid hormone synthesis and secretion in chronic renal failure
Published in Nephrology, dialysis, transplantation (Print) (1996)Get full text
Conference Proceeding