Search Results - "Kilarski, W W"

Transcellular Pathways in Lymphatic Endothelial Cells Regulate Changes in Solute Transport by Fluid Stress by Triacca, Valentina, Güç, Esra, Kilarski, Witold W, Pisano, Marco, Swartz, Melody A

“…RATIONALE:The transport of interstitial fluid and solutes into lymphatic vessels is important for maintaining interstitial homeostasis and delivering antigens…”
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Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing by Martino, Mikaël M., Briquez, Priscilla S., Güç, Esra, Tortelli, Federico, Kilarski, Witold W., Metzger, Stephanie, Rice, Jeffrey J., Kuhn, Gisela A., Müller, Ralph, Swartz, Melody A., Hubbell, Jeffrey A.

“…Growth factors (GFs) are critical in tissue repair, but their translation to clinical use has been modest. Physiologically, GF interactions with extracellular…”
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Biomechanical regulation of blood vessel growth during tissue vascularization by Kilarski, Witold W, Gerwins, Pär, Samolov, Branka, Petersson, Ludvig, Kvanta, Anders

“…In this report, Witold Kilarski et al . show that the rapid formation of new vessels in healing wound tissue does not depend on endothelial cell proliferation…”
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Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation by Procopio, Maria-Giuseppina, Laszlo, Csaba, Al Labban, Dania, Kim, Dong Eun, Bordignon, Pino, Jo, Seung-Hee, Goruppi, Sandro, Menietti, Elena, Ostano, Paola, Ala, Ugo, Provero, Paolo, Hoetzenecker, Wolfram, Neel, Victor, Kilarski, Witold W., Swartz, Melody A., Brisken, Cathrin, Lefort, Karine, Dotto, G. Paolo

“…Stromal fibroblast senescence has been linked to ageing-associated cancer risk. However, density and proliferation of cancer-associated fibroblasts (CAFs) are…”
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Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions by Vokali, Efthymia, Yu, Shann S., Hirosue, Sachiko, Rinçon-Restrepo, Marcela, V. Duraes, Fernanda, Scherer, Stefanie, Corthésy-Henrioud, Patricia, Kilarski, Witold W., Mondino, Anna, Zehn, Dietmar, Hugues, Stéphanie, Swartz, Melody A.

“…Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in the lymph nodes, and can cross-present antigens to naïve CD8 + T…”
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Perivascular Macrophages Limit Permeability by He, Huanhuan, Mack, Julia J, Güç, Esra, Warren, Carmen M, Squadrito, Mario Leonardo, Kilarski, Witold W, Baer, Caroline, Freshman, Ryan D, McDonald, Austin I, Ziyad, Safiyyah, Swartz, Melody A, De Palma, Michele, Iruela-Arispe, M Luisa

“…OBJECTIVE—Perivascular cells, including pericytes, macrophages, smooth muscle cells, and other specialized cell types, like podocytes, participate in various…”
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Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice by Potez, Marine, Trappetti, Verdiana, Bouchet, Audrey, Fernandez-Palomo, Cristian, Güç, Esra, Kilarski, Witold W, Hlushchuk, Ruslan, Laissue, Jean, Djonov, Valentin

“…The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study,…”
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Photoactivation of lysosomally sequestered sunitinib after angiostatic treatment causes vascular occlusion and enhances tumor growth inhibition by Nowak-Sliwinska, P, Weiss, A, van Beijnum, J R, Wong, T J, Kilarski, W W, Szewczyk, G, Verheul, H M W, Sarna, T, van den Bergh, H, Griffioen, A W

“…The angiogenesis inhibitor sunitinib is a tyrosine kinase inhibitor that acts mainly on the VEGF and PDGF pathways. We have previously shown that sunitinib is…”
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Inherent biomechanical traits enable infective filariae to disseminate through collecting lymphatic vessels by Kilarski, Witold W., Martin, Coralie, Pisano, Marco, Bain, Odile, Babayan, Simon A, Swartz, Melody A.

“…Filariases are diseases caused by arthropod-borne filaria nematodes. The related pathologies depend on the location of the infective larvae when their…”
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Intravital immunofluorescence for visualizing the microcirculatory and immune microenvironments in the mouse ear dermis by Kilarski, Witold W, Güç, Esra, Teo, Jeremy C M, Oliver, S Ryan, Lund, Amanda W, Swartz, Melody A

“…Visualizing the dynamic behaviors of immune cells in living tissue has dramatically increased our understanding of how cells interact with their surroundings,…”
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The dual role of tumor lymphatic vessels in dissemination of metastases and immune response development by Stachura, Joanna, Wachowska, Malgorzata, Kilarski, Witold W., Güç, Esra, Golab, Jakub, Muchowicz, Angelika

“…Lymphatic vasculature plays a crucial role in the immune response, enabling transport of dendritic cells (DCs) and antigens (Ags) into the lymph nodes…”
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ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells by Mężyk-Kopeć, Renata, Wyroba, Barbara, Stalińska, Krystyna, Próchnicki, Tomasz, Wiatrowska, Karolina, Kilarski, Witold W, Swartz, Melody A, Bereta, Joanna

“…Tumor-associated lymphatic vessels actively participate in tumor progression and dissemination. ADAM17, a sheddase for numerous growth factors, cytokines,…”
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VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy by Rutkowski, Joseph M, Ihm, Jong Eun, Lee, Seung Tae, Kilarski, Witold W, Greenwood, Veronique I, Pasquier, Miriella C, Quazzola, Alexandra, Trono, Didier, Hubbell, Jeffrey A, Swartz, Melody A

“…Lymphatic vessels surround follicles within the ovary, but their roles in folliculogenesis and pregnancy, as well as the necessity of lymphangiogenesis in…”
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Recent developments in tumor angiogenesis by Kilarski, W W, Bikfalvi, A

“…Angiogenesis is a developmental process that also plays the central role in adults during the female menstruation cycle, wound healing and neoplastic growth…”
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Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton by Kilarski, Witold W, Jura, Natalia, Gerwins, Pär

“…Inhibition of angiogenesis could be a treatment strategy for diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy. PP2 is a pharmacological…”
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Glycoconjugates of the intestinal goblet cells of four cyprinids by Fiertak, A, Kilarski, W M

“…The aim of this work was to show differences in the terminal and subterminal sugar composition of carbohydrate chains of glycoconjugates produced by the goblet…”
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Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling by Güç, Esra, Briquez, Priscilla S, Foretay, Didier, Fankhauser, Manuel A, Hubbell, Jeffrey A, Kilarski, Witold W, Swartz, Melody A

“…Abstract Lymphangiogenesis occurs in inflammation and wound healing, yet its functional roles in these processes are not fully understood. Consequently,…”
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Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model by Soulet, Fabienne, Kilarski, Witold W, Antczak, Philipp, Herbert, John, Bicknell, Roy, Falciani, Francesco, Bikfalvi, Andreas

“…Modern functional genomic approaches may help to better understand the molecular events involved in tissue morphogenesis and to identify molecular signatures…”
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Changes of Connexin43 Expression in Non‐pregnant Porcine Myometrium Correlate with Progesterone Concentration During Oestrous Cycle by Karasinski, J, Galas, J, Semik, D, Fiertak, A, Bilinska, B, Kilarski, WM

“…Connexin43 (Cx43) is a major protein of myometrial gap junctions. The number of Cx43 gap junctions increase dramatically with the onset of labour in…”
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Methods for Mapping the Extracellular and Membrane Proteome in the Avian Embryo, and Identification of Putative Vascular Targets or Endothelial Genes by Kilarski, Witold W, Herbert, John, Bikfalvi, Andreas

“…We present a protocol for the specific labeling and isolation of proteins from the membrane surface of endothelial cells and the surrounding extracellular…”
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