Search Results - "Kikuchi, Matsuo"

Research on and developmental strategy of anti-asthmatic agents by Totsuka, Ryuichi, Kikuchi, Matsuo

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Eotaxin-2 Alters Eosinophil Integrin Function via Mitogen-Activated Protein Kinases by Tachimoto, Hiroshi, Kikuchi, Matsuo, Hudson, Sherry A, Bickel, Carol A, Hamilton, Robert G, Bochner, Bruce S

“…Adhesion molecules and chemokines contribute to selective eosinophil recruitment in allergic inflammation. In this study, we examined the effects of eotaxin-2,…”
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A Novel Anti-Allergic Drug, Betotastine Besilate, Suppresses Interleukin-5 Production by Human Peripheral Blood Mononuclear Cells by KAMINUMA, Osamu, OGAWA, Koji, KIKKAWA, Hideo, KIKUCHI, Matsuo, NAITO, Kazuaki, IKEZAWA, Katsuo

“…The effect of a novel anti-allergic drug, betotastine besilate (betotasitine) on intertleukin (IL)-5 production by human peripheral blood mononuclear cells…”
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Anti-allergic activity of betotastine besilate (TAU-284), a new anti-allergic drug by Yato, N, Murata, T, Saito, N, Sakai, A, Kikuchi, M, Tsuzurahara, K, Narita, H

“…The anti-allergic activity of betotastine besilate (betotastine), a new anti-allergic drug, was investigated in several allergy models of rats in comparison…”
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4-Acylaminophenol Derivatives as Novel Lipoxygenase Inhibitors : Synthesis and Inhibitory Effect on 5-Lipoxygenase and Leukotriene B4 Production by KIKUCHI, Matsuo, HASHIMURA, Yoshimasa, TSUZURAHARA, Kei, NAGASAWA, Masaaki, INOUE, Hirozumi, TANIGUCHI, Tomoyasu, UCHIDA, Tomofumi

“…Structure-activity relationships in the inhibitory effects of 4-acylaminophenol derivatives on the 5-lipoxygenase (5-LOX) from RBL-1 cells and leukotriene B4…”
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Inhibitory effects Of a 4-acylaminophenol derivative (T-0757), a novel 5-lipoxygenase inhibitor, on leukotriene B4 production and neutrophil infiltration in arachidonic acid and zymosan induced inflammation in rats by Kikuchi, Matsuo, Tsuzurahara, Kei

“…We already reported that a 4-acylaminophenol derivative (T-0757：N-(3,5-dimethyl-4-hydroxyphenyl)-3,7-dimethyl-(2,E)-2,6- octadienoic amide) inhibited…”
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Inhibitory Effect of 4-Acylaminophenol Derivatives (T-0799 and T-0757), Novel Lipoxygenase Inhibitors, on Arachidonic Acid-Induced Infiltration of Polymorphonuclear Leukocytes in Rat Skin by Kikuchi, Matsuo, Ishikawa, Setsuko, Tsuzurahara, Kei

“…Effects of 4-acylaminophenol derivatives, novel 5-lipoxygenase inhibitors, on the neutrophil infiltration in arachidonic acid (AA) (10 mg/site)-induced skin…”
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CCR3-Active Chemokines Promote Rapid Detachment of Eosinophils from VCAM-1 In Vitro by Tachimoto, Hiroshi, Burdick, Monica M, Hudson, Sherry A, Kikuchi, Matsuo, Konstantopoulos, Konstantinos, Bochner, Bruce S

“…Selective eosinophil recruitment is the result of orchestrated events involving cell adhesion molecules, chemokines, and their receptors. The mechanisms by…”
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Dynamics of antigen‐specific helper T cells at the initiation of airway eosinophilic inflammation by Kaminuma, Osamu, Fujimura, Hisako, Fushimi, Keiko, Nakata, Aya, Sakai, Atsuko, Chishima, Susumu, Ogawa, Koji, Kikuchi, Matsuo, Kikkawa, Hideo, Akiyama, Kazuo, Mori, Akio

“…Bronchial asthma is characterized by chronic eosinophilic inflammation of the bronchial mucosa in which Th2 cells play crucial roles. Ovalbumin‐reactive Th2…”
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Biological activity of l-o-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine(platelet activating factor) by Hayashi, Masahiko, Kikuchi, Matsuo, Kiyomiya, Kenichi, Oh-ishi, Sachiko

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Involvement of Histamine in Vascular Permeability Increase of the Rat Pleurisy Induced by Phorbol Myristate Acetate by KIKUCHI, Matsuo, OH-ISHI, Sachiko

“…Rat pleurisy was induced by an intrapleural injection of 1 nmol (0.1 ml) of phorbol myristate acetate (PMA). Accumulation of pleural fluid peaked at a volume…”
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Studies on a New Antiallergic Pyridinecarboxamide TA-5707F and Its Sodium Salt (TA-5707) II. Mechanism of Antiallergic Action of TA-5707 by TSUZURAHARA, Kei, ISHIKAWA, Setsuko, ONO, Yasutoshi, MURATA, Takashi, KIKUCHI, Matsuo, TAKEYAMA, Shigeyuki

“…Mechanism of the antiallergic action of 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide (TA-5707F) was studied using the water-soluble sodium salt…”
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INVOLVEMENT OF LEUKOTRIENE B4 IN ZYMOSAN-INDUCED RAT PLEURISY by KIKUCHI, Matsuo, TSUZURAHARA, Kei, NAITO, Kazuaki

“…The role of leukotriene B4 (LTB4) in leukocyte infiltration in zymosan induced rat pleurisy was investigated by studying the effects of 5-lipoxygenase…”
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Phorbol esters alter alpha4 and alphad integrin usage during eosinophil adhesion to VCAM-1 by Kikuchi, Matsuo, Tachimoto, Hiroshi, Nutku, Esra, Hudson, Sherry A, Bochner, Bruce S

“…We examined the effect of the protein kinase C activator phorbol-12-myristate-13-acetate (PMA) on the human eosinophil adhesion molecule phenotype and…”
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Inhibition of pulmonary eosinophilia does not necessarily prevent the airway hyperresponsiveness induced by Sephadex beads by Matsubara, S, Fushimi, K, Ogawa, K, Kikkawa, H, Nakata, A, Kameda, R, Kikuchi, M, Naito, K, Ikezawa, K

“…The Lewis rat among highly inbred strains exhibits significant airway hyperresponsiveness (AHR) following intravenous administration of Sephadex G-200…”
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INVOLVEMENT OF LEUKOTRIENE B4 IN ZYMOSAN-INDUCED RAT PLEURISY : INHIBITION OF LEUKOCYTE INFILTRATION BY THE 5-LIPOXYGENASE INHIBITOR T-0757 by KIKUCHI, Matsuo, TSUZURAHARA, Kei, NAITO, Kazuaki

“…The role of leukotriene B4 (LTB4) in leukocyte infiltration in zymosan induced rat pleurisy was investigated by studying the effects of 5-lipoxygenase…”
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Involvement of leucotriene B4 in zymosan-induced rat pleurisy: inhibitation of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757 by KIKUCHI, Matsuo, TSUZURAHARA, Kei, NAITO, Kazuaki

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4-Acylaminophenol Derivatives as Novel Lipoxygenase Inhibitors by KIKUCHI, Matsuo, HASHIMURA, Yoshimasa, TSUZURAHARA, Kei, NAGASAWA, Masaaki, INOUE, Hirozumi, TANIGUCHI, Tomoyasu, UCHIDA, Tomofumi

“…Structure-activity relationships in the inhibitory effects of 4-acylaminophenol derivatives on the 5-lipoxygenase (5-LOX) from RBL-1 cells and leukotriene B4…”
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Inhibitory effect of betotastine besilate on antigen-induced airway eosinophil infiltration and peripheral blood eosinophilia in mice by Sakai, A, Kikuchi, M, Yato, N, Kikkawa, S, Saito, N, Narita, H

“…Eosinophilic inflammations has been recognized as a characteristic of allergic diseases. The effect of betotastine besilate (betotastine, CAS 125602-71-3,…”
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Search of chemical mediators with the inflammatory model: (2)Involvement of arachidonic acid metabolites in rat pleurisy by Kiyomiya, Kenichi, Kikuchi, Matsuo, Hayashi, Masahiko, Oh-ishi, Sachiko

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