Search Results - "Kiktev, Denis"

GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae by Kiktev, Denis A., Sheng, Ziwei, Lobachev, Kirill S., Petes, Thomas D.

“…The chromosomes of many eukaryotes have regions of high GC content interspersed with regions of low GC content. In the yeast Saccharomyces cerevisiae, high-GC…”
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Dual role of ribosome-associated chaperones in prion formation and propagation by Chernoff, Yury O., Kiktev, Denis A.

“…Chaperones of the diverse ubiquitous Hsp70 family are involved in the regulation of ordered self-perpetuating protein aggregates (amyloids and prions),…”
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Regulation of Chaperone Effects on a Yeast Prion by Cochaperone Sgt2 by Kiktev, Denis A., Patterson, Jesse C., Müller, Susanne, Bariar, Bhawana, Pan, Tao, Chernoff, Yury O.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of the Cell Asymmetry Apparatus and Ribosome-Associated Chaperones in the Destabilization of a Saccharomyces cerevisiae Prion by Heat Shock by Howie, Rebecca L, Jay-Garcia, Lina Manuela, Kiktev, Denis A, Faber, Quincy L, Murphy, Margaret, Rees, Katherine A, Sachwani, Numera, Chernoff, Yury O

“…Self-perpetuating transmissible protein aggregates, termed prions, are implicated in mammalian diseases and control phenotypically detectable traits in Yeast…”
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Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair by McGinty, Ryan J, Rubinstein, Rachel G, Neil, Alexander J, Dominska, Margaret, Kiktev, Denis, Petes, Thomas D, Mirkin, Sergei M

“…Improper DNA double-strand break (DSB) repair results in complex genomic rearrangements (CGRs) in many cancers and various congenital disorders in humans…”
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Yeast Short-Lived Actin-Associated Protein Forms a Metastable Prion in Response to Thermal Stress by Chernova, Tatiana A., Kiktev, Denis A., Romanyuk, Andrey V., Shanks, John R., Laur, Oskar, Ali, Moiez, Ghosh, Abheek, Kim, Dami, Yang, Zhen, Mang, Maggie, Chernoff, Yury O., Wilkinson, Keith D.

“…Self-perpetuating ordered protein aggregates (amyloids and prions) are associated with a variety of neurodegenerative disorders. Although environmental agents…”
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The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe–S cluster in DNA polymerase δ by Kiktev, Denis A, Dominska, Margaret, Zhang, Tony, Dahl, Joseph, Stepchenkova, Elena I, Mieczkowski, Piotr, Burgers, Peter M, Lujan, Scott, Burkholder, Adam, Kunkel, Thomas A, Petes, Thomas D

“…Abstract Iron-sulfur clusters (4Fe–4S) exist in many enzymes concerned with DNA replication and repair. The contribution of these clusters to enzymatic…”
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Feedback control of prion formation and propagation by the ribosome‐associated chaperone complex by Kiktev, Denis A., Melomed, Mikhail M., Lu, Caroline D., Newnam, Gary P., Chernoff, Yury O.

“…Summary Cross‐beta fibrous protein aggregates (amyloids and amyloid‐based prions) are found in mammals (including humans) and fungi (including yeast), and are…”
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Poly(A)-Binding Protein Acts in Translation Termination via Eukaryotic Release Factor 3 Interaction and Does Not Influence [PSI+] Propagation by Cosson, Bertrand, Couturier, Anne, Chabelskaya, Svetlana, Kiktev, Denis, Inge-Vechtomov, Sergey, Philippe, Michel, Zhouravleva, Galina

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Prion-Dependent Lethality of sup45 Mutants in Saccharomyces cerevisiae by Kiktev, Denis A., Inge-Vechtomov, Sergey, Zhouravleva, Galina

“…In yeast Saccharomyces cerevisiae, translation termination factors eRF1 (Sup45) and eRF3 (Sup35) are encoded by essential genes SUP45 and SUP35, respectively…”
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The translation termination factor eRF1 (Sup45p) of Saccharomyces cerevisiae is required for pseudohyphal growth and invasion by Petrova, Alexandra, Kiktev, Denis, Askinazi, Olga, Chabelskaya, Svetlana, Moskalenko, Svetlana, Zemlyanko, Olga, Zhouravleva, Galina

“…Mutations in the essential genes SUP45 and SUP35, encoding yeast translation termination factors eRF1 and eRF3, respectively, lead to a wide range of…”
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Role of the Cell Asymmetry Apparatus and Ribosome-Associated Chaperones in the Destabilization of a Saccharomyces cerevisiae Prion by Heat Shock by Howie, Rebecca L, Jay-Garcia, Lina Manuela, Kiktev, Denis A, Faber, Quincy L, Murphy, Margaret, Rees, Katherine A, Sachwani, Numera, Chernoff, Yury O

“…Self-perpetuating protein aggregates (prions) cause diseases in mammals. Yeast prions are heritable in cell divisions. Howie et al. demonstrate that the…”
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Role of the Cell Asymmetry Apparatus and Ribosome-Associated Chaperones in the Destabilization of a Saccharomyces cerevisiae Prion by Heat Shock by Howie, Rebecca L, Jay-Garcia, Lina Manuela, Kiktev, Denis A, Faber, Quincy L, Murphy, Margaret, Rees, Katherine A, Sachwani, Numera, Chernoff, Yury O

“…Self-perpetuating protein aggregates (prions) cause diseases in mammals. Yeast prions are heritable in cell divisions. Howie et al. demonstrate that the…”
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paradox of viable sup45 STOP mutations: a necessary equilibrium between translational readthrough, activity and stability of the protein by Kiktev, Denis, Moskalenko, Svetlana, Murina, Olga, Baudin-Baillieu, Agnès, Rousset, Jean-Pierre, Zhouravleva, Galina

“…The mechanisms leading to non-lethality of nonsense mutations in essential genes are poorly understood. Here, we focus on the factors influencing viability of…”
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