Search Results - "Kikkawa, U"

Calcineurin-mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation by Huang, C-C, Wang, J-M, Kikkawa, U, Mukai, H, Shen, M-R, Morita, I, Chen, B-K, Chang, W-C

“…The proto-oncogene c-Jun plays an important role in regulating tumor progression. We previously reported that the serine/threonine phosphatase calcineurin…”
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Activation of RAC-Protein Kinase by Heat Shock and Hyperosmolarity Stress through a Pathway Independent of Phosphatidylinositol 3-Kinase by Konishi, Hiroaki, Matsuzaki, Hidenori, Tanaka, Motonari, Ono, Yoshitaka, Tokunaga, Chiharu, Kuroda, Shun'ichi, Kikkawa, Ushio

“…RAC protein kinase (RAC-PK), a serine/threonine protein kinase containing a pleckstrin homology (PH) domain, was activated by cellular stress such as heat…”
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Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties by Ono, Y, Fujii, T, Ogita, K, Kikkawa, U, Igarashi, K, Nishizuka, Y

“…The primary structure of the zeta subspecies of rat brain protein kinase C was deduced from its overlapping cDNAs. The zeta subspecies of protein kinase C…”
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The structure, expression, and properties of additional members of the protein kinase C family by Ono, Y, Fujii, T, Ogita, K, Kikkawa, U, Igarashi, K, Nishizuka, Y

“…In rat brain three members of the protein kinase C family encoded by cDNAs termed delta, epsilon, and zeta were newly identified by molecular cloning and…”
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Preferential Fas-mediated apoptotic execution at G1 phase: the resistance of mitotic cells to the cell death by Hashimoto, T, Juso, K, Nakano, M, Nagano, T, Kambayashi, S, Nakashima, A, Kikkawa, U, Kamada, S

“…Apoptosis is induced by various stresses generated from the extracellular and intracellular environments. The fidelity of the cell cycle is monitored by…”
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Phorbol Ester Binding to Protein Kinase C Requires a Cysteine-Rich Zinc-Finger-Like Sequence by Ono, Yoshitaka, Fujii, Tomoko, Igarashi, Koichi, Kuno, Takayoshi, Tanaka, Chikako, Kikkawa, Ushio, Nishizuka, Yasutomi

“…Protein kinase C normally has a tandem repeat of a characteristic cysteine-rich sequence in C1, the conserved region of the regulatory domain. These sequences…”
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Cell Division Arrest Induced by Phorbol Ester in CHO Cells Overexpressing Protein Kinase C-δ Subspecies by Watanabe, Tatsuya, Ono, Yoshitaka, Taniyama, Yoshio, Hazama, Kumiko, Igarashi, Koichi, Ogita, Kouji, Kikkawa, Ushio, Nishizuka, Yasutomi

“…Several lines of CHO cells stably overexpressing protein kinase C (PKC) subspecies to various extents were established by the DNA-mediated transfer. Upon…”
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Isolation and Characterization of the ε Subspecies of Protein Kinase C from Rat Brain by Koide, Hiroshi, Ogita, Kouji, Kikkawa, Ushio, Nishizuka, Yasutomi

“…The ε subspecies of protein kinase C (ε PKC) was purified to near homogeneity from the soluble fraction of rat brain by successive chromatographies on…”
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The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II by Meek, D. W., Simon, S., Kikkawa, U., Eckhart, W.

“…The entire coding sequence of wild‐type mouse p53 was expressed in Escherichia coli under control of the PL promoter of bacteriophage lambda. The bacterial p53…”
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The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase C zeta by Konishi, H, Kuroda, S, Kikkawa, U

“…Binding proteins to the pleckstrin homology domain of RAC protein kinase were screened by using glutathione S-transferase fusion protein system. Proteins in…”
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Distribution of protein kinase C-like immunoreactive neurons in rat brain by Saito, N, Kikkawa, U, Nishizuka, Y, Tanaka, C

“…Distribution of protein kinase C in the CNS of rat is presented based on immunohistochemical analysis with monoclonal antibodies against this protein kinase…”
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Effects of knockout of the protein kinase C beta gene on glucose transport and glucose homeostasis by Standaert, M L, Bandyopadhyay, G, Galloway, L, Soto, J, Ono, Y, Kikkawa, U, Farese, R V, Leitges, M

“…The beta-isoform of protein kinase C (PKC) has paradoxically been suggested to be important for both insulin action and insulin resistance as well as for…”
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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters by Castagna, M, Takai, Y, Kaibuchi, K, Sano, K, Kikkawa, U, Nishizuka, Y

“…Tumor-promoting phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA) directly activate in vitro Ca2+-activated, phospholipid-dependent protein…”
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Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters by Kikkawa, U, Takai, Y, Tanaka, Y, Miyake, R, Nishizuka, Y

“…A tumor-promoting phorbol ester, [3H]phorbol-12,13-dibutyrate, may bind to a homogeneous preparation of Ca2+-activated, phospholipid-dependent protein kinase…”
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Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta by Konishi, H, Shinomura, T, Kuroda, S, Ono, Y, Kikkawa, U

“…cDNAs of RAC protein kinases (RAC-PK) alpha and beta were cloned from a rat testis cDNA library. The predicted open reading frames encode 480 and 481 amino…”
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Purification, Characterization, and Sequence Determination of Phospholipase D Secreted by Streptoverticillium cinnamoneum by Ogino, Chiaki, Negi, Yukinari, Matsumiya, Toshiko, Nakaoka, Koichi, Kondo, Akihiko, Kuroda, Shun'ichi, Tokuyama, Shinji, Kikkawa, Ushio, Yamane, Tsuneo, Fukuda, Hideki

“…Phospholipase D (PLD), secreted into the culture medium of an actinomycete, Streptoverticillium cinnamoneum, has been purified to homogeneity and…”
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Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover by Kishimoto, A, Takai, Y, Mori, T, Kikkawa, U, Nishizuka, Y

“…Ca2+-activated, phospholipid-dependent protein kinase from various mammalian tissues (Takai, Y., Kishimoto, A., Iwasa, Y., Kawahara, Y., Mori, T., and…”
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The Protein Kinase C Family: Heterogeneity and its Implications by Kikkawa, U, Kishimoto, A, Nishizuka, Y

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A novel phosphatidylserine-binding peptide motif defined by an anti-idiotypic monoclonal antibody. Localization of phosphatidylserine-specific binding sites on protein kinase C and phosphatidylserine decarboxylase by Igarashi, K, Kaneda, M, Yamaji, A, Saido, T C, Kikkawa, U, Ono, Y, Inoue, K, Umeda, M

“…A monoclonal anti-idiotypic antibody, Id8F7, previously shown to bind to a phosphatidylserine (PS)-specific binding site on protein kinase C (PKC) has been…”
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Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties by Kikkawa, U, Takai, Y, Minakuchi, R, Inohara, S, Nishizuka, Y

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