Search Results - "Kiger, John A."
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Bursicon Signaling Mutations Separate the Epithelial-Mesenchymal Transition From Programmed Cell Death During Drosophila melanogaster Wing Maturation
Published in Genetics (Austin) (01-10-2008)“…Following eclosion from the pupal case, wings of the immature adult fly unfold and expand to present a flat wing blade. During expansion the epithelia, which…”
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Functional Dissection of Neuroanatomical Loci Regulating Ethanol Sensitivity in Drosophila
Published in The Journal of neuroscience (01-11-2002)“…Ethanol has complex but similar effects on behavior in mammals and the fruit fly Drosophila melanogaster. In addition, genetic and pharmacological approaches…”
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3
Tissue remodeling during maturation of the Drosophila wing
Published in Developmental biology (01-01-2007)“…The final step in morphogenesis of the adult fly is wing maturation, a process not well understood at the cellular level due to the impermeable and refractive…”
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Hemocytes are Essential for Wing Maturation in Drosophila melanogaster
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2001)“…Newly eclosed flies have wings that are highly folded and compact. Within an hour, each wing has expanded, the dorsal and ventral cuticular surfaces bonding to…”
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Transgenic inhibitors identify two roles for protein kinase A in drosophila development
Published in Genetics (Austin) (01-05-1999)“…We have initiated an analysis of protein kinase A (PKA) in Drosophila using transgenic techniques to modulate PKA activity in specific tissues during…”
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Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster
Published in Nature (London) (01-01-1981)“…Cyclic AMP is an intracellular mediator ('second messenger') in the nervous and endocrine control of cellular function, regulating different processes in…”
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Sexual hyperactivity and reduced longevity of dunce females of Drosophila melanogaster
Published in Genetics (Austin) (01-01-1987)“…The dunce gene of Drosophila melanogaster codes for a cyclic adenosine-3',5'-monophosphate-specific phosphodiesterase. Mutations of dunce alter or abolish the…”
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Genetic evidence for a protein kinase A/cubitus interruptus complex that facilitates processing of cubitus interruptus in Drosophila
Published in Genetics (Austin) (01-07-2001)“…Hedgehog (Hh) activates a signal transduction pathway regulating Cubitus interruptus (Ci). In the absence of Hh, full-length Ci (Ci-155) is bound in a complex…”
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GENETIC ANALYSIS OF CHROMOMERE 3D4 IN DROSOPHILA MELANOGASTER: THE DUNCE AND SPERM-AMOTILE GENES
Published in Genetics (Austin) (01-04-1982)“…Both male and female Drosophila that are homozygous deficient for chromomere 3D4 are viable but sterile and lack detectable cAMP-specific phosphodiesterase…”
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A cytogenetic analysis of cyclic nucleotide phosphodiesterase activities in Drosophila [melanogaster]
Published in Genetics (Austin) (01-04-1977)“…The genome of Drosophila melanogaster has been surveyed for chromosomal regions which exert a dosage effect on the activities of cAMP phosphodiesterase or cGMP…”
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A genetically distinct form of cyclic AMP phosphodiesterase associated with chromomere 3D4 in Drosophila melanogaster
Published in Genetics (Austin) (01-03-1979)“…Two cyclic AMP phosphodiesterase enzymes (E.C.3.1.4.17) are present in homogenates of adult Drosophila melanogaster. The two enzymes differ from one another in…”
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The consequences of nullosomy for a chromosomal region affecting cyclic AMP phosphodiesterase activity in Drosophila [melanogaster]
Published in Genetics (Austin) (01-04-1977)“…A study of Drosophila nullosomic for chromomere 3D4 shows that this region of the genome is necessary for male fertility, normal female fertility and normal…”
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13
DNA of Vegetative Bacteriophage Lambda, VI. Electron Microscopic Studies of Replicating Lambda DNA
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1971)“…Electron micrographs of replicating lambda DNA molecules, during the period of progeny-particle DNA formation, show single-tailed circular structures. The…”
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14
Two Drosophila learning mutants, dunce and rutabaga, provide evidence of a maternal role for cAMP on embryogenesis
Published in Developmental biology (01-06-1987)“…The dunce gene of Drosophila melanogaster encodes a cAMP-specific phosphodiesterase (form II). Mutant dunce flies have elevated levels of cAMP and exhibit a…”
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Genetic evidence for a protein kinase A/Cubitus interruptus complex that facilitates processing of Cubitus interruptis in Drosophila
Published in Genetics (Austin) (01-07-2001)“…Kiger and O'She examine hedgehog (Hh) target gene expression caused by mutant forms of protein kinase A regulatory (PKAr) and catalytic (PKAc) subunits and by…”
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A kinetic study of cyclic adenosine 3':5'-monophosphate binding and mode of activation of protein kinase from Drosophila melanogaster embryos
Published in Biochemistry (Easton) (25-07-1978)“…Cyclic AMP-dependent protein kinase and its regulatory subunit were isolated from Drosophila melanogaster embryos. The profiles of cyclic AMP binding by these…”
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Genetic analysis of chromomere 3D4 in Drosophila melanogaster. II: Regulatory sites for the dunce gene
Published in Genetics (Austin) (01-10-1984)“…Chromomere 3D4 of the X chromosome of D. melanogaster contains two genes, dunce (dnc) and sperm amotile (sam). Mutations in dnc cause defects in memory…”
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The inability of yeast transfer RNA to suppress an amber mutation in an E. coli system
Published in Genetics (Austin) (01-01-1973)“…Transfer RNA from super-suppressor mutants of Saccharomyces cerevisiae cannot suppress an amber mutation in vitro in an E. coli protein synthesizing system. It…”
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Participation by Drosophila transfer RNA in protein synthesis in an E.coli protein synthesizing system
Published in Nucleic acids research (01-10-1974)“…Drosophila melanogaster tyrosyl-tRNATyr is shown to participate directly and with high efficiency in an E. coli protein synthesizing system employing…”
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dunce mutants of Drosophila melanogaster: mutants defective in the cyclic AMP phosphodiesterase enzyme system
Published in The Journal of cell biology (01-07-1981)“…The cyclic AMP and cyclic GMP phosphodiesterase activities present in flies of six mutant strains of the dunce gene and in the parent wild-type strains are…”
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