Search Results - "Kifuji, Takayuki"
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Discovery of evocalcet, a next-generation calcium-sensing receptor agonist for the treatment of hyperparathyroidism
Published in Bioorganic & medicinal chemistry letters (15-06-2018)“…[Display omitted] •Optimization from cinacalcet resulted in the discovery of evocalcet.•CYP2D6 inhibition observed in cinacalcet is completely solved in…”
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Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin in Japanese Patients with Type 2 Diabetes Mellitus
Published in Advances in therapy (01-08-2015)“…Introduction Canagliflozin is a sodium glucose co-transporter 2 inhibitor approved worldwide for the treatment of patients with type 2 diabetes mellitus…”
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Absorption, disposition and metabolic pathway of amiselimod (MT-1303) in healthy volunteers in a mass balance study
Published in Xenobiotica (02-09-2019)“…The absorption, metabolism and excretion of MT-1303 were investigated in healthy male subjects after a single oral dose of 0.4 mg [14C]-MT-1303…”
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