Search Results - "Kierstead, Richard W."

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    Aromatic esters of 5-O-desosaminylerythronolide A oxime by LeMahieu, Ronald A, Carson, Mathew, Kierstead, Richard W, Pestka, Sidney

    Published in Journal of medicinal chemistry (01-08-1975)
    “…Several substituted aromatic esters of the C-3 hydroxyl of 5-O-desosaminylerythronolide A oxime were prepared. Ribosomal binding studies showed that meta…”
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    Pentadienyl carboxamide derivatives as antagonists of platelet activating factor by Guthrie, Robert W, Kaplan, Gerald L, Mennona, Francis A, Tilley, Jefferson W, Kierstead, Richard W, Mullin, John G, LeMahieu, Ronald A, Zawoiski, Sonja, O'Donnell, Margaret

    Published in Journal of medicinal chemistry (01-08-1989)
    “…A series of N-[4-(3-pyridinyl)butyl]-5,5-disubstituted-pentadienamides was prepared and evaluated for PAF-antagonist activity. Compounds were assayed in vitro…”
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    Propenyl carboxamide derivatives as antagonists of platelet-activating factor by Guthrie, Robert W, Kaplan, Gerald L, Mennona, Francis A, Tilley, Jefferson W, Kierstead, Richard W, O'Donnell, Margaret, Crowley, Herman, Yaremko, Bohdan, Welton, Ann F

    Published in Journal of medicinal chemistry (01-10-1990)
    “…A series of N-[4-(3-pyridinyl)butyl] 3-substituted propenyl carboxamide derivatives bearing an unsaturated bicyclic moiety in the 3-position was prepared and…”
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    Antihypertensive (2-aminoethyl)thiourea derivatives. 1 by Tilley, Jefferson W, Levitan, Paul, Kierstead, Richard W, Cohen, Michael

    Published in Journal of medicinal chemistry (01-12-1980)
    “…Structure-activity studies were carried out on a series of antihypertensive 1-(2-aminoethyl)-3-(substituted phenyl)thioureas. From this class of compounds, the…”
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    Ellipticine derivatives by Guthrie, Robert W, Brossi, Arnold, Mennona, Francis A, Mullin, John G, Kierstead, Richard W, Grunberg, E

    Published in Journal of medicinal chemistry (01-07-1975)
    “…Several acyloxy and alkyl derivatives of ellipticine have been prepared. In addition, a modified synthesis leading to the hitherto unobtainable 8,9-dimethoxy-…”
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    Pyrido[2,1-b]quinazolinecarboxylic acids as orally active antiallergy agents by Tilley, Jefferson W, LeMahieu, Ronald A, Carson, Mathew, Kierstead, Richard W, Baruth, Herman W, Yaremko, Bohdan

    Published in Journal of medicinal chemistry (01-01-1980)
    “…A series of 8-substituted pyrido[2,1-]quinazoline-2-carboxylic acids was prepared by the nickel carbonyl mediated carboxylation of the corresponding bromides…”
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    Synthesis of heterocyclic analogs of α-methyldopa by Tilley, Jefferson W., Levitan, Paul, Kierstead, Richard W.

    Published in Journal of heterocyclic chemistry (01-03-1979)
    “…The condensation of various halomethyl heterocycles with the potassium salt of the alanine derivative 3, followed by hydrolysis, gave a series of novel…”
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    Insulin Normalization as an Approach to the Pharmacological Treatment of Obesity by Campfield, L. Arthur, Smith, Françoise J., Mackie, Garry, Tenenbaum, Renata, Sassano, Mary Lisa, Mullin, John, Kaiser, Ken, Kierstead, Richard W.

    Published in Obesity research (01-11-1995)
    “…Hyperinsulinemia and exaggerated insulin response to glucose are among the hallmarks of obesity. However, the role of hyperinsulinemia in the etiology and…”
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