Search Results - "Kien Hui, Chua"
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Biosafety evaluation of culture-expanded human chondrocytes with growth factor cocktail: a preclinical study
Published in Scientific reports (09-12-2020)“…The scarcity of chondrocytes is a major challenge for cartilage tissue engineering. Monolayer expansion is necessary to amplify the limited number of…”
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Abelmoschus Esculentus (L.) Moench's Peel Powder Improves High-Fat-Diet-Induced Cognitive Impairment in C57BL/6J Mice
Published in International journal of environmental research and public health (30-07-2020)“…Okra peel exhibits numerous therapeutic effects. This study explores the potential ameliorative effects of okra peel powder on high-fat-diet (HFD)-induced…”
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3
Piper sarmentosum Roxb. Inhibits Angiotensin-Converting Enzyme Activity in Phorbol 12-Myristate-13-Acetate-Induced Endothelial Cells
Published in International journal of molecular sciences (28-02-2024)“…Angiotensin-converting enzyme (ACE) plays a crucial role in the pathogenesis of hypertension. Roxb., an herb known for its antihypertensive effect, lacks a…”
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Human adipose-derived mesenchymal stem cells promote recovery of injured HepG2 cell line and show sign of early hepatogenic differentiation
Published in Cytotechnology (Dordrecht) (01-08-2018)“…Currently, orthotopic liver transplantation is the gold standard therapy for liver failure. However, it is limited by the insufficient organ donor and risk of…”
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comparison between tocotrienol and omeprazole on gastric growth factors in stress-exposed rats
Published in World journal of gastroenterology : WJG (28-08-2017)“…AIM To investigate and compare the effects of tocotrienol and omeprazole on gastric growth factors in rats exposed to water-immersion restraint…”
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Role of Rutin on Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells
Published in TheScientificWorld (01-01-2014)“…Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), is a major antiatherogenic factor in the blood vessel. Oxidative stress plays an…”
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7
Acanthamoeba-mediated cytopathic effect correlates with MBP and AhLBP mRNA expression
Published in Parasites & vectors (28-12-2017)“…In recent years, the concern of Acanthamoeba keratitis has increased since the infection is often associated with contact lens use. Partial 18S rRNA genotypic…”
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Stichopus chloronotus aqueous extract as a chondroprotective agent for human chondrocytes isolated from osteoarthitis articular cartilage in vitro
Published in Cytotechnology (Dordrecht) (01-04-2019)“…The proinflammatory cytokines, metalloproteinases family (MMPs), inflammatory mediators PGE2, COX-2 and NO are the most important group of compounds…”
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Characterization of human adipose-derived stem cells and expression of chondrogenic genes during induction of cartilage differentiation
Published in Clinics (São Paulo, Brazil) (01-01-2012)“…Understanding the changes in chondrogenic gene expression that are involved in the differentiation of human adipose-derived stem cells to chondrogenic cells is…”
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Shelf-life evaluation of bilayered human skin equivalent, MyDerm
Published in PloS one (23-08-2012)“…Skin plays an important role in defense against infection and other harmful biological agents. Due to its fragile structure, skin can be easily damaged by…”
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Gelam honey promotes ex vivo corneal fibroblasts wound healing
Published in Cytotechnology (Dordrecht) (01-12-2019)“…This study evaluated the effects of Gelam honey (GH) on ex vivo corneal fibroblast ulcer model via wound healing assay, gene expression and…”
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12
Effects of epidermal growth factor on the proliferation and cell cycle regulation of cultured human amnion epithelial cells
Published in Journal of bioscience and bioengineering (01-08-2012)“…Human amnion epithelial cells (HAECs) hold great promise in tissue engineering for regenerative medicine. Large numbers of HAECs are required for this purpose…”
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Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts
Published in Journal of biomedicine & biotechnology (01-01-2011)“…This study determined the molecular mechanisms of tocotrienol-rich fraction (TRF) in preventing cellular senescence of human diploid fibroblasts (HDFs)…”
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Pro‐angiogenic potential of human chorion‐derived stem cells: in vitro and in vivo evaluation
Published in Journal of cellular and molecular medicine (01-05-2013)“…Human chorion‐derived stem cells (hCDSC) were previously shown to demonstrate multipotent properties with promising angiogenic characteristics in…”
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Tocotrienol Attenuates Stress-Induced Gastric Lesions via Activation of Prostaglandin and Upregulation of COX-1 mRNA
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…The present study aims to distinguish the effect of tocotrienol on an important gastric protective factor, prostaglandin E2 (PGE2), in stress-induced gastric…”
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Endogenous and induced angiogenic characteristics of human chorion-derived stem cells
Published in Cell biology international (01-12-2012)“…Cell‐based therapy using stem cells has emerged as one of the pro‐angiogenic methods to enhance blood vessel growth and sprouting in ischaemic conditions. This…”
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Gamma-Tocotrienol Modulated Gene Expression in Senescent Human Diploid Fibroblasts as Revealed by Microarray Analysis
Published in Oxidative medicine and cellular longevity (01-01-2013)“…The effect of γ-tocotrienol, a vitamin E isomer, in modulating gene expression in cellular aging of human diploid fibroblasts was studied. Senescent cells at…”
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Value of human amniotic epithelial cells in tissue engineering for cornea
Published in Human cell : official journal of Human Cell Research Society (01-11-2010)“…Human amniotic epithelial cells (hAECs) are potentially one of the key players in tissue engineering due to their easy availability. The aim of the present…”
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Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells
Published in Biochemical and biophysical research communications (30-05-2014)“…•Hypoxia maintains the stemness of adipose-derived stem cells (ASCs).•ASCs show an increased proliferation rate under low oxygen tension.•Oxygen level as low…”
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20
Pharmacotherapy of Alzheimer's Disease: Seeking Clarity in a Time of Uncertainty
Published in Frontiers in pharmacology (24-03-2020)“…Alzheimer's disease (AD) is recognized as a major health hazard that mostly affects people older than 60 years. AD is one of the biggest medical, economic, and…”
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