Search Results - "Kieltyka, Roxanne"
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Dynamic Exchange in 3D Cell Culture Hydrogels Based on Crosslinking of Cyclic Thiosulfinates
Published in Angewandte Chemie International Edition (05-02-2024)“…Dynamic polymer materials are highly valued substrates for 3D cell culture due to their viscoelasticity, a time‐dependent mechanical property that can be tuned…”
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Hierarchical Formation of Supramolecular Transient Networks in Water: A Modular Injectable Delivery System
Published in Advanced materials (Weinheim) (22-05-2012)“…A modular one‐component supramolecular transient network in water, based on poly(ethylene glycol) and end‐capped with four‐fold hydrogen bonding units, is…”
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NIR-Light-Driven Generation of Reactive Oxygen Species Using Ru(II)-Decorated Lipid-Encapsulated Upconverting Nanoparticles
Published in Langmuir (17-09-2019)“…The biological application of ruthenium anticancer prodrugs for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) is restricted by the need to…”
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Stimuli-Responsive Polymers at the Interface with Biology
Published in Biomacromolecules (09-09-2024)“…There has been growing interest in polymeric systems that break down or undergo property changes in response to stimuli. Such polymers can play important roles…”
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Switching the Mode of Drug Release from a Reaction-Coupled Low-Molecular-Weight Gelator System by Altering Its Reaction Pathway
Published in Biomacromolecules (09-01-2023)“…Low-molecular-weight hydrogels are attractive scaffolds for drug delivery applications because of their modular and facile preparation starting from…”
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6
Hydrophobic domain modulation of chemical responsiveness in a bolaamphiphile-based supramolecular monomer
Published in Chembiochem : a European journal of chemical biology (21-08-2024)“…Self-immolative chemistries that respond in an irreversible manner to external stimuli are highly attractive to permanently degrade filamentous supramolecular…”
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Thiosquaramide-Based Supramolecular Polymers: Aromaticity Gain in a Switched Mode of Self-Assembly
Published in Journal of the American Chemical Society (25-11-2020)“…Despite a growing understanding of factors that drive monomer self-assembly to form supramolecular polymers, the effects of aromaticity gain have been largely…”
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Aromatic Gain in a Supramolecular Polymer
Published in Angewandte Chemie International Edition (01-09-2015)“…The synergy of aromatic gain and hydrogen bonding in a supramolecular polymer is explored. Partially aromatic bis(squaramide) bolaamphiphiles were designed to…”
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Structure to Function in Supramolecular Polymers and Materials
Published in Macromolecular rapid communications. (01-09-2018)Get full text
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Photopatternable, Branched Polymer Hydrogels Based on Linear Macromonomers for 3D Cell Culture Applications
Published in ACS macro letters (16-06-2020)“…Photochemical ligation strategies in hydrogel materials are crucial to model spatiotemporal phenomena that occur in the natural extracellular matrix. We here…”
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A Platinum Supramolecular Square as an Effective G-Quadruplex Binder and Telomerase Inhibitor
Published in Journal of the American Chemical Society (06-08-2008)“…In this contribution, we report that a self-assembled platinum molecular square [Pt(en)(4,4′-dipyridyl)]4 can act as an efficient G-quadruplex binder and…”
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Stab2-Mediated Clearance of Supramolecular Polymer Nanoparticles in Zebrafish Embryos
Published in Biomacromolecules (09-03-2020)“…Supramolecular polymers are attractive scaffolds for use as nanocarriers in drug delivery thanks to their modularity and easy fabrication; however, a molecular…”
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Dynamics of dual-fluorescent polymersomes with durable integrity in living cancer cells and zebrafish embryos
Published in Biomaterials (01-06-2018)“…The long-term fate of biomedical nanoparticles after endocytosis is often only sparsely addressed in vitro and in vivo, while this is a crucial parameter to…”
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A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium
Published in Advanced healthcare materials (01-01-2014)“…Minimally invasive intervention strategies after myocardial infarction use state‐of‐the‐art catheter systems that are able to combine mapping of the infarcted…”
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Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives
Published in Biomacromolecules (09-04-2018)“…Synthetic hydrogel materials can recapitulate the natural cell microenvironment; however, it is equally necessary that the gels maintain cell viability and…”
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Spatial and Temporal Modulation of Cell Instructive Cues in a Filamentous Supramolecular Biomaterial
Published in ACS applied materials & interfaces (20-04-2022)“…Supramolecular materials provide unique opportunities to mimic both the structure and mechanics of the biopolymer networks that compose the extracellular…”
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Mesoscale Modulation of Supramolecular Ureidopyrimidinone-Based Poly(ethylene glycol) Transient Networks in Water
Published in Journal of the American Chemical Society (31-07-2013)“…In natural systems, highly synergistic non-covalent interactions among biomolecular components exert mesoscopic control over hierarchical assemblies. We herein…”
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18
Crosslinker‐Induced Effects on the Gelation Pathway of a Low Molecular Weight Hydrogel
Published in Advanced materials (Weinheim) (01-03-2017)“…The use of polymeric crosslinkers is an attractive method to modify the mechanical properties of supramolecular materials, but their effects on the…”
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Mesoscale characterization of supramolecular transient networks using SAXS and rheology
Published in International journal of molecular sciences (16-01-2014)“…Hydrogels and, in particular, supramolecular hydrogels show promising properties for application in regenerative medicine because of their ability to adapt to…”
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Platinum Phenanthroimidazole Complexes as G-Quadruplex DNA Selective Binders
Published in Chemistry : a European journal (28-01-2008)“…Complexes that bind and stabilize G‐quadruplex DNA structures are of significant interest due to their potential to inhibit telomerase and halt tumor cell…”
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